Indications / Non-small cell lung cancer · Breast cancer · Pancreatic cancer · Colorectal cancer · Acute myeloid leukemia · Chronic myeloid leukemia · Multiple myeloma · Glioblastoma · Glioma · Neuroblastoma · Medulloblastoma · Diffuse midline glioma (DIPG) · Ependymoma · Atypical teratoid rhabdoid tumour (AT/RT) · Childhood acute lymphoblastic leukemia · Ewing sarcoma · Osteosarcoma · Rhabdomyosarcoma
Non-small cell lung cancer
EGFR, ALK, KRAS G12C and the ADC wave in first and later lines.
AACR Annual Meeting 2026
17–22 Apr 2026, San Diego · Cancer Research 86 (7_Supplement)
All 7,489 abstracts, including clinical trial (CT) and late-breaking (LB) abstracts, have Cancer Research supplement DOIs in Crossref.
Headline and verified abstracts
10 abstracts found by Parallel web research on 2026-11-11 and verified: 7 checked on the source page, 3 on a second source. Rows that could not be verified were dropped. Titles and metadata only; abstract text is not stored.
- CT014Oral presentation
- CT015Oral presentationClinical outcomes by genomic markers and ctDNA dynamics with perioperative nivolumab (NIVO) for resectable NSCLC from CheckMate 77TBohnetCheckMate 77TnivolumabVerified on source pageaacrjournals.org
- CT020Oral presentation
- CT021Oral presentation
- CT038Oral presentation
- CT231Oral presentation
- CT233Oral presentation
- CT299Oral presentationDirozalkib versus crizotinib in advanced ALK-positive non-small cell lung cancer (NSCLC): Results from the multicenter, randomized, open-label phase 3 trialYing Liu (presented by Haifeng Liu)dirozalkibcrizotinibVerified on a second sourceaacrjournals.org
- CT300Oral presentationTaletrectinib in tyrosine kinase inhibitor (TKI)-naïve patients with ROS1+ non-small cell lung cancer (NSCLC): Updated data from TRUST-I and TRUST-IILyudmila BazhenovaTRUST-I and TRUST-IItaletrectinibVerified on source pageaacrjournals.org
- CT301Oral presentation
Indexed in Crossref
182 abstracts matching non-small cell lung cancer from the meeting's journal supplement, fetched live from Crossref 2026-11-12 09:24 UTC. This is a keyword search, not the complete abstract book.
- CT252Double lung transplantation in patients with metastatic lung-limited non-small cell lung carcinoma (NSCLC): A case seriesYoung Kwang Chae, Liam Il-Young Chung, Ronald Seungjune Min, Sanghwa Kim et al.
- 6460Immunologic and transcriptional features associated with long-term response and resistance to immune checkpoint inhibitors in non-small cell lung cancer checkpoint inhibitors in non-small cell lung cancerYoshihiro Masui, Tatsuya Yoshida, Jun Miyakoshi, Ryoko Higashiyama et al.
- CT251Genomic clonality analysis of patients with metastatic lung-limited non-small cell lung carcinoma (NSCLC) who underwent double lung transplantation (DLT) across timepoints and tumor regionYoung Kwang Chae, Sanghwa Kim, Liam Il-Young Chung, Ronald Seungjune Min et al.
- 4229AI based explainable survival modeling for advanced non small cell lung cancerKang Qin, An Qin, John V. Heymach
- 3922Polymeric delivery of TRAIL mRNA for inducing apoptosis in non-small cell lung cancer.Gurkirat Singh Sandhu, Hasan Uludag.
- 7412ANXA1 and MYADM regulate CD4+T cell differentiation and exhaustion in non-small cell lung cancer (NSCLC)Minyeop Kim, Youwon Lee, Seung Yeon Oh, Eun Ji Lee et al.
- 1736Synergistic anticancer activity of ciclopirox and prexasertib in non-small cell lung cancer cellsZhu Huang, Bing Cheng, Shile Huang
- LB491PET imaging and response to amivantamab treatment of non-small cell lung cancer xenograftsMann Dangarwala, Aldred Mendez, Bernadette Marquez-Nostra
- 3730Spatial determinants of TILs in immunotherapy sensitivity of patients with non-small cell lung cancer (NSCLC)Miguel Lopez de Rodas Gregorio, Ravi Kamble, Matthew Blair, Yao Nie et al.
- 4107Factors associated with early treatment discontinuation in the AACR Project GENIE Biopharma Collaborative (BPC) non-small cell lung cancer (NSCLC) cohortDany Hamze, Sanjay Mishra, Aleenah Mohsin, Sarah Minuit et al.
- 2605Concordance evaluation of plasma whole-exome sequencing (pWES) and tissue whole-exome sequencing (tWES): A pilot study in non-small cell lung cancer (NSCLC)Bingjie Dong, Zhijiao Wang, Carol E. Peña, Xiaoqiao Liu et al.
- 2599Methylation-based circulating tumor DNA predicts recurrence in definitively treated non-small cell lung cancer (NSCLC)Jisoo Lee, Eun Ji Song, Youngjun Lee, Jongsu Kim et al.
- 2504Activation of alternative receptor by CCL5 is associated with non-small cell lung cancer disparitiesBriana Alicia Brock, Murugesh Eswaran, Hina Mir, Shailesh Singh
- 3436Emerging evidence of cellular dormancy programs in non-small cell lung cancer (NSCLC)Grace Ha, Melissa Tracy, Anthony Griffen, Daniel Bravo et al.
- 5369CCR8+ regulatory T cells represent a promising prognostic marker for non-small cell lung cancer (NSCLC).Santosh K. Singh, Manoj K. Mishra, Eric Flenaugh, Gabriella M. Oprea-Ilies et al.
- 5548Unbiased discovery of novel macrophage-activating immunotherapies for ALK+ non-small cell lung cancerCarlota Pages-Geli, Thomas Wienclaw, Juliano Ribeiro, Matheus Silva et al.
- 2985TRIB2 as a therapeutic vulnerability in ALK-rearranged non-small cell lung cancerJitender Monga, Sudha Sadasivan, Sang-Yoon Lee, Sharad K. Suthar et al.
- 5244Genomic HLA class I allelic imbalance undermines enduring immunotherapy response in advanced non small cell lung cancerYiting Dong, Shun Wang, Wenbin Li, Zhijie Wang et al.
- 6620CYLD induces ferroptosis through ALOX12B to enhance radiosensitivity in non-small cell lung cancer.Yihan Xu, Jiazhuo Yan, Huiwen Yu, Lu Zhang et al.
- 5885Targeting myeloid-derived suppressor cells (MDSCs) to restore antitumor immunity in non-small cell lung cancer (NSCLC) via SRC family kinase Inhibition with NXP900Bobby Kaghazchi, In Hwa Um, Amber Ortiz, Enrique Podarosu et al.
- 4734Metabolomic profiling among non-small cell lung cancer and non-cancer populations: A case-control studyYoo-Min Koh, Jae Jeong Yang, Mi-Jeong Yoo, Qiuyin Cai et al.
- 2833Amivantamab restores antitumor immunity in non-small cell lung cancer through EGFR/MET expression-dependent mechanismsTakamasa Ishino, Ryo Yoshichika, Fumiaki Mukohara, Ken Suzawa et al.
- CT243Dirozalkib in patients with advanced ALK-positive non-small cell lung cancer (NSCLC): Results from a phase 2 studyYing Liu, Yan Yu, Zhiye Zhang, Ruiling Ning et al.
- 1881Understanding evolutionary and ecological mechanisms of sotorasib resistance in KRAS G12C-mutant non-small cell lung cancer.Jinling Wu, Mina Nguyen Dinh, Arda Durmaz, Maximilian Strobl et al.
- 3675Identifying determinants of molecular testing for advanced non-small cell lung cancer in the rural United StatesDena Rhinehart, Amanda L. Blackford, Kristen Marrone, Craig Pollack et al.
- CT245PDR001 in patients with unresectable non-small cell lung cancer (NSCLC) harboring KRAS/NRAS mutation or without actionable genetic abnormalities: Phase II, multicenter, single arm studyYeong Hak Bang, Seong-Eun Kim, Shinkyo Yoon, Dae Ho Lee et al.
- 4243Mutational-signature adjusted models reveal HLA-mediated depletion of antigenic mutations in non-small cell lung cancer (NSCLC)Amy Lauren Cummings, Andy Han, Seung J. Park, Sai S. Kollapaneni et al.
- LB418RELATIVITY-104 Part 2: translational analyses in the programmed death ligand 1 (PD-L1) ≥ 1% and non-squamous (NSQ) non-small cell lung cancer (NSCLC) subgroupJaclyn Neely, Annie Yu, Nicolas Girard, Manuel Cobo-Dols et al.
- 2851EGFR-TKI drives the reprogramming of CD8+ T cell immunity in non-small cell lung cancerSsu-Pei Yu, Hao-Chen Chi, Meng-Yun Lin, Chao-Chi Ho et al.
- 4474Cannabidiol enhances etoposide efficacy in non-small cell lung cancer by engaging a p53-mTOR-TFEB lysosomal death program.Youngsic Jeon, Hyukjoon Kwon, Young Nyun Park, Taejung Kim et al.
- 6422A 3D bioprinted vascularized tumor tissue model of non-small cell lung cancer: A model for drug screeningFahimeh Shahabipour, Yuchi Chen, Yen-Ting Tung, Min Jae Song et al.
- 5258Monitoring of molecular response during immunotherapy by circulating tumor DNA in non-small cell lung cancerJohanna Svensson, Maria Yhr, Per Torstensson, Levent Akyürek et al.
- 1660Design of a synthetic non-natural antibody (NoNabody) against GRP as a new therapy for small cell lung cancerPablo Garrido Rodriquez, Jahaziel Gasperin Bulbarela, Alexei Fedorovish Licea Navarro, Alfredo Martínez
- 1395The distribution of non-small cell lung cancer early phase clinical trial sites within and outside the United StatesBrittany Avin McKelvey, Luke Saxton-Stivers, Tod Guidry, Andrea E. Ferris
- 6637Real world outcomes for patients with KRAS G12D -mutated non-small cell lung cancer: A University of California Health Data Warehouse retrospective analysis.Jingtong Liang, Tali Azenkot, Sandip Patel
- 4109Pan-cancer landscape of IDH1/2 mutations with a focus on non-small cell lung cancer: Insights from the AACR GENIE RegistryZhaohui L. Arter, Cathleen Park, Misako Nagasaka, Sai-Hong I. Ou
- 1490A single cell-based protein activity landscape for human small cell lung cancerLucas ZhongMing Hu, Anish Thomas, Andrea Califano
- 3963Spatially Resolved Cell-Cell Communication Reveals Intra-tumoral heterogeneity in Small Cell Lung CancerTingxiao Gao, Jalal Kazan, Fatema Zohora, Gregory Schwartz et al.
- 391TROP2 and PTEN are biomarkers of primary resistance to TUSC2 gene therapy in non-small cell lung cancer (NSCLC).Ismail M. Meraz, Renduo Song, Shuhong Wu, Yi Xu et al.
- 3166TKI adaptive resistance in HER2-driven non-small cell lung cancer at minimal residual disease stage can be targeted using cell surface-directed therapiesManale El Kharbili, Daniel Wilkinson, Lauren Giesy, Sharon R. Pine et al.
- 1409Fusion epigenotyping using cell-free DNA methylation improves detection of actionable ALK fusions in non-small cell lung cancer.Laura Tung, Anton Valouev, Justin Odegaard, Lauren Lawrence et al.
- 3453Macrophage polarization in ALK+ non-small cell lung cancer: Implications for treatment targetingMarisa E. Aikins, Abdullah Saeed, Derek Nancarrow, Peter J. Ulintz et al.
- 2942Inhibition of stearoyl-CoA desaturase 1 (SCD1) by SSI-4 as a therapeutic strategy in non-small cell lung cancer.Valeria Romina Salerno Gonzales, Lauren Antal, Tamiel Nichole Turley, John A. Copland
- 7034The potential of dequalinium chloride and osimertinib combination in overcoming osimertinib acquired resistance in EGFR-mutant non-small cell lung cancer.Jing Sun, Dongsheng Wang, Suresh S. Ramalingam, Zhen Chen et al.
- 2600Investigating treatment response and resistance in non-small cell lung cancer patients through epigenetic profiling of plasma nucleosomesChristoffer T. Maansson, Simone Stensgaard, Emma Pedersen, Anders Lade Nielsen et al.
- 1045A novel epithelial tumor signature predicts survival and response to PD-1 blockade in non-small cell lung cancerMuaath Alsufi, Jehad Yasin, Muthafar Alsufi, Osama Younis et al.
- 80Quantitative assessment of tumor-infiltrating lymphocytes using AI in non-small cell lung cancer and association with immunotherapy response.Mona Tuysserkani, Siraj Ali, Yoojoo Lim, Ken Nesmith et al.
- 6584Spatial mapping and significance of IL12 signaling in non-small cell lung cancerJuan Guiza, Lucy Zheng, Barani Kumar Rajendran, Luciene Borges et al.
- 2820Spatial mapping of PD1-PD-L2 interactions suggests an additional checkpoint axis in non-small cell lung cancerAnna Gorbunova, Amanda Lindberg, Lars Muhl, Ghazal Lessan Toussi et al.
- 3400A 3D bioprinted hydrogel-based tumor model of non-small cell lung cancer for preclinical drug testingJan A. Schlegel, Julia Thiel, Kanstantsin Lashuk, Schueler Julia et al.
- 1047MORPHEUS-lung: Biomarkers and clinical response to atezolizumab + bevacizumab + stereotactic body radiotherapy in patients with metastatic non-small cell lung cancerByoung Chul Cho, Sun Min Lim, Sang Hoon Lee, Dong Kwon Kim et al.
- 5338Clinicogenomic predictors of first-line immune checkpoint inhibitor outcomes in non-small cell lung cancer: A nationwide C-CAT cohort from Japan.Mika Iwasaki, Takahiro Ando, Koki Fujii, Kousuke Watanabe et al.
- 1976Pathogenic germline KEAP1 variants drive constitutive NRF2 hyperactivation and enhanced oncogenic fitness in non small cell lung cancer.Laura Eibler, Miika M. Mehine, Rebecca Caeser, Esther Redin et al.
- 2192SLFN5 mediates liquid-to-solid phase transition of NOTCH1 to suppress stemness and radioresistance of non-small cell lung cancer.Mi Tang, Lu Zhang, Jiaxin Zhao, Hongji Dai et al.
- 7029Engineering isogenic models harboring resistance mechanisms to the latest-generation EGFR inhibitor in non-small cell lung cancer.Hyeyoun Chang, Florencia M. Rowdo, Kirsty Wienand, John G. Foulke et al.
- LB013Lorlatinib in advanced ALK-positive non-small cell lung cancer: Efficacy, safety and exploration of predictive biomarkers for therapeutic responseFang Wei, Linyan Tian, Huiyang Shi, Wenxin Jiang et al.
- CT212Neratinib efficacy in second line patients with EGFR exon 18-mutant non-small-cell lung cancerSteve Shen, Wenfeng Fang, Ning Li, Runxiang Yang et al.
- 3296The receptor-like protein tyrosine phosphatase PTPRH modulates dephosphorylation of the tyrosine kinases EPHA2 and EGFR, alters cell morphology and adhesion, and behaves as a tumor-suppressor in non-small cell lung cancer cellMylena Ortiz, Deeya Patel, Jesus Garcia-Lerena, Andrew C. Nelson et al.
- 2221Tumor-associated CD207+ cDC2 drives TLS formation via TNF family cytokines in non-small cell lung cancer.Youngtaek Kim, Gang-Taik Lee, Dong Kwon Kim, JuHyeon Lee et al.
- 1664Novel GPC3-targeting antibody-drug conjugate using novel payload or dual payloads to treat hepatocellular carcinoma and non-small-cell lung cancerSuk Lee, John Liu, Alice Juang, Aastha Jain et al.
- 2713Ensemble machine learning using unmatched pre-treated multi-omic data can classify response to immune checkpoint inhibition in non-small cell lung cancer.Alexander Azizi, Arvind Ravi, Natalie Vokes, Stephen-John Sammut et al.
- 2830Immunomodulatory response in Dato-DXd-treated non-small cell lung cancer patient-derived organotypic tumor spheroids (pDOTS)Satoru Yasuda, Patrick Hall Lizotte, Elena Ivanova, Zhaorong Li et al.
- 6393Polo-like kinase 4 inhibition enhances radiosensitivity in non-small cell lung cancer via apoptosis and epithelial-mesenchymal transition regulation.Hye Won Lee, Shin Kim, Jeong-Woo Hwang, Eun-Young Gong et al.
- 2815Cytoplasmic PD-L1 levels are associated with tumor progression in small cell lung cancerJi Young Lee, Anindita Das, HyeonJoo Cheon
- 4736Trace metal signatures in non-small cell lung cancer: A pilot study of patients attended at Mount Sinai Hospital in New York CityDiddier Prada, Manish Arora, Julio landero, Jamshid Abdul Ghafar et al.
- 1536CADM1-CAR T cells targeting neuroendocrine subtypes of small cell lung cancerShiva Krishna Katkam, Sergei Chuikov, Zhefan Wang, Venkateshwar Keshamouni
- 2092Single-cell RNA sequencing reveals ancestry-associated molecular and cellular immunosuppressive features in non-small cell lung cancer.Liang Liu, Pengbo Zhang, Enzo Palma, Ashley Ballard et al.
- 7013
- 1457Prediction of gene expression and molecular pathway activity from H&E whole slide images in non-small cell lung cancer.Mina Khoshdeli, Muhammad Sohaib, Mohammed Qutaish, Mahesh Bachu et al.
- 3620The human virome and its association with clinical benefit of immune checkpoint inhibitor therapy among patients with advanced non-small cell lung cancerAnna E. Coghill, Jin Xu, Aleksandr Lazaryan, Doratha Armenthus Byrd et al.
- 5428Impact of double primary cancer on survival in patients with non-small cell lung cancer: Large-scale cohort.Hyun Ae Jung, Sang Ah Chi, Allison Park, Sehhoon Park et al.
- 2307Body mass index-associated transcriptomic signatures reveal immune, stromal, and metabolic rewiring in non-small cell lung cancer: Insights into the obesity paradoxRoberto Borea, Eswar Shankar, Francesco Drago, Carlos Ayala de Miguel et al.
- CT140Final Results from S2302—PRAGMATICA-LUNG: A prospective randomized study of ramucirumab plus pembrolizumab (RP) versus standard of care (SOC) for participants (pts) previously treated with immunotherapy for stage IV or recurrent non-small cell lung cancer (NSCLC)Karen L. Reckamp, Mary W. Redman, Konstantin H. Dragnev, Maya Khalil et al.
- 464Assessment of tumor heterogeneity for Integrin beta-6 expression in non-squamous non-small cell lung cancer specimens using an investigational Integrin beta-6 IHC assay.Stefanie Nicole Kapucija, Jim Christian, Dana Sprague, Nicole Medina et al.
- LB144OBX-115 membrane-bound IL15 (mbIL15)-expressing engineered tumor-infiltrating lymphocytes (TIL) overcome target cell immune evasion related to major histocompatibility complex (MHC) silencing through both direct killing and transactivation of NK cells in patient-derived autologous non-small cell lung cancer (NSCLC) modelsAdam J. Schoenfeld, Alonso Villasmil Ocando, Zheng Ao, Rachel Burga et al.
- 7753Circulating thymidine kinase activity (TKa) as a predictive and dynamic biomarker in the metastatic non-small cell lung cancer (NSCLC): Immunoblood studyMaristella Giammaruco, Lorenza Landi, Mattias Bergqvist, Gabriele Minuti et al.
- CT244Taletrectinib in tyrosine kinase inhibitor (TKI)-pretreated patients with ROS1+ non-small cell lung cancer (NSCLC): Updated data from TRUST-I and TRUST-IIGeoffrey Liu, Jorge Nieva, Lyudmila Bazhenova, Chang-Min Choi et al.
- 100Blood-based integration of epigenomic profiles, TMB, and MSI to predict immune checkpoint inhibitor response in advanced non-small cell lung cancer (aNSCLC).Sean Gordon, Jing Wang, Shile Zhang, Marisa Juntilla et al.
- 3098Discovery of the RAD51 inhibitor JKYN-1 and characterization of its anticancer activity in preclinical models of non-small cell lung cancerYifan Yu, Morgan Black, Nikolina Radulovich, Peter Ferguson et al.
- LB127Drivers and patterns of disease progression as a novel schema for risk stratification in metastatic non-small cell lung cancerGabriela R. Esnaola, Mengru Wang, Jeffrey J. Ishizuka, Benjamin J. Resio et al.
- 6649Comparative risk of secondary central nervous system metastases in metastatic non-small cell lung cancer: A real-world propensity-matched analysis of pembrolizumab vs atezolizumab monotherapy conducted on TriNetX.Umer Rizwan, Athar Nawab, Syed Najafi, Karandeep Bawa et al.
- 4833Identification of protein kinase signaling networks activating partial EMT as therapeutic targets in non-small cell lung cancerMohaddase Hamidi, Kenneth Omolo, Amir Yarmahmoodi, Margret B. Einarson et al.
- 1134Cell-free DNA fragmentomes capture response to immuno-radiotherapy in metastatic non-small cell lung cancerNoushin Niknafs, Lavanya Sivapalan, Bahar Alipanahi, Gavin Pereira et al.
- 5333Profiling membrane antigen expression of select antibody-drug conjugate (ADC) targets in EGFR -altered non-small cell lung cancer treated with osimertinib.Kevin Lu, Tali Azenkot, Ellen B. Jaeger, Unnati Jariwala et al.
- 2109Analysis of collagen architecture in brain metastasis and paired primary tumors in Non-small cell lung cancer supports the recruitment of fibroblasts originating outside the brain.Jordi Alcaraz, Alejandro Bernardo Suarez, Gabriela Caballero, Patricia Fernandez-Nogueira et al.
- 11Artificial intelligence-based spatial analysis of the local tumor microenvironment in relation to c-MET expression in non-small cell lung cancer.Ji-Hyang Lee, Joshua Littrell, Chiyoon Oum, Taebum Lee et al.
- 1130Tracing tumor-specific EV-miRNA signatures via patient-derived explant models to advance liquid biopsy in non-small cell lung cancerMiranda Burdiel, Carlos Rodriguez-Antolin, Ana Arauzo-Cabrera, Olga Pernía et al.
- 761Collagen turnover is dominated by fibrogenesis in lung adenocarcinoma and fibrolysis in lung squamous cell carcinomas.Victoria Batto, Marselina Arshakyan, Rasmus Sund Pedersen, Neel Ingemann Nissen et al.
- 1026The copy number amplification of MYCL indicated activation of angiogenesis in small cell lung cancerZihang Yuan, Jingwei Zhang, Yan Ju, Xingyuan Wu et al.
- 1553Combining PD-1 blockade with DLL3-targeted T cell engager potentiates antitumor efficacy in small cell lung cancerTongxin Huo, Ting Ni, Jingjing Wang, Panpan Wang et al.
- 2937Imipridones ONC201, ONC206, and ONC212 show potent killing and colony arrest of small-cell lung cancer cell lines.Audrey Y. Su, Connor Purcell, Shengliang Zhang, Lanlan Zhou et al.
- 4735Designing a novel 3D co-culture model incorporating patient T-cells to study lipid metabolism as a metabolic vulnerability in KRAS driven non-small cell lung cancerSaoirse Flanagan, Robyn Stanley, Sze Ying Tan, Beatrice Malacrida et al.
- 1212Spatial transcriptomics reveals distinct SPP1-CD44 signaling networks in neoadjuvant osimertinib treated EGFR mutant non-small cell lung cancer.Whitney Tamaki, Daniel L. Kerr, Wei Wu, Grant Eilers et al.
- 6562Identifying vulnerabilities to immune checkpoint inhibitors of oncogene-addicted non-small cell lung cancer subgroupsInés Díaz-Cano, José Gracia, Patricia Cozar, Belén Revuelta et al.
- 7736Rare EGFR cis compound L833V/H835L mutation in non-small cell lung cancer is oncogenic and a therapeutic target of EGFR tyrosine kinase inhibitorsYo Han Jeon, Ahjin Lim, Myung Kyung Choi, Hee Seong Choi et al.
- 1507Health behavior associated CCL20 ligand variation contributes to the disparity in non-small cell lung cancerMurugesh Eswaran, Briana Alicia Brock, Hina Mir, Sejong Bae et al.
- 6501Preclinical evidence for synergistic activity of alectinib and everolimus in ALK-positive non-small cell lung cancerHamadi Madhi, Habib Serhan, Rachel Mercer, Benjamin Levy et al.
- 2446High PRMT5 expression is associated with decreased immune infiltrate and worse outcomes to immune checkpoint inhibitors in non-small cell lung cancerNatalie Vokes, Stamatina Fragkogianni, Pooja A. Shah, Santiago G. Trevino et al.
- 5423A Bayesian framework for evaluating somatic copy number variants into comparative genomic analysis of multifocal non-small cell lung cancer.Claire Teigen, Ying-Chun Lo, Sounak Gupta, Stephanie Smoley et al.
- 6009Mitochondrial glutathione reductase as a redox vulnerability in KEAP1/NRF2-mutant non-small cell lung cancerYun Huang, Chao Ting, Jing-Chun Lin, Ryan Martin et al.
- 7742Intratumoral effector T-cells and macrophages underlie prolonged survival after PD-1 axis blockade in metastatic non-small cell lung cancer (mNSCLC)Daniel Boiarsky, Thazin Nwe Aung, Anna Wurtz, Jianlei Gu et al.
- 7025Mechanisms of zongertinib resistance in HER2-mutant non-small cell lung cancer and potential strategies to overcome resistance.Yuji Shibata, Monique B. Nilsson, Ximeng Liu, Li (Lily) Cai et al.
- 1897Targeting RB-deficient small cell lung cancer with selective CDK2 inhibition by AZD8421.Rajita Vatapalli, Michael Grondine, Jun Fan, Grace Guo et al.
- 1716AT06 is a bispecific antibody drug conjugate targeting DLL3 and SEZ6 with potent activity in small cell lung cancer (SCLC) modelsBin Zou, Bryan K. Yeung, Nannan Lang
- 50Spatial transcriptomics uncovers patterns of transcriptional reprogramming and immune evasion in small cell lung cancer.Emmanuel S. Spanos, Meng Wang, Amin Sabet, Esther Redin et al.
- 1538Oncostatin-M ligand-based CAR T-cell therapy targets and eliminates lung adenocarcinomaKayla Klatt, Daniel Feinberg, Reshmi Parameswaran
- 3717DLL3-targeted in vivo CAR-T therapy of small cell lung cancer with lipid nanoparticles and circular RNAYishan Ma, Jingsheng Cai, Yufei Xia, Xiaonan Huang et al.
- 1526Nanobody-based, DLL3-directed FAST-CAR T-cell therapy for small cell lung cancer (SCLC)Qi Dong, Wenjie Yin, Xiangling Dai, Tao Wang et al.
- LB314Whole genome methylation sequencingstrongly suggests a novel, non-stem cell origin for some lung adenocarcinomasNicholas Juul, Diego Almanza, Maximilian Diehn, Tushar Desai
- 1611Development of a T cell engager against IGFBPL1: A novel target for small cell lung cancer and other neuroendocrine cancersLauren A. Pitt, Eleanor Leung, Ruban Kannan, Shereen Jabar et al.
- 7502Spindle assembly checkpoint integrity determines sensitivity to KIF18A inhibition in small-cell lung cancerChiori Tabe, Rajesh Kumar, Yang Zhang, Yue Huang et al.
- 5718Cbx5 as a potential target to enhance immunotherapy in small cell lung cancerHong Cao, Yiting Li, Jiajia Gu, Yuan Hao et al.
- 5339Prevalence and distinct biological programs of small cell lung cancer molecular subtypes revealed by real-world clinico-genomics database.Yige Luo, Lujia Wang, Nadine Jahchan, Peter Ansell et al.
- 3379Small cell lung cancer humanized mouse models identifies unique T cell infiltration immune phenotypes in response to combination immune-radiation therapiesBell Wu, Xiaozhuo Ran, Olivia Huang, Lifang Song et al.
- 250Targeting DNA damage repair pathway and CCR2+ myeloid cell to overcome radioimmunotherapy resistance in small cell lung cancer.Zhuoran Yao, Hui Wang, Kai Kang, Min Yu et al.
- 5964Single-cell multi-omics profiling unveils the regulatory mechanisms of small cell lung cancerCharny Park, Namhee Yu, Jung-Hyun Kim, Sehwa Hong et al.
- 7745EGFR-TKI enhances anti-CD47 antibody-mediated macrophage phagocytosis in EGFR-mutant non-small cell lung cancerMyungja Ro, Seung Min Yang, Youngtaek Kim, Min-Hak Lee et al.
- 5240A CXCL10/11 and CCL19 duplex chromogenic assay complements PD-L1 immunohistochemistry in non-small cell lung cancerAlexander L. Tang, Liad Elmelech, William L. Tang, Maxwell Spurrell et al.
- 2431Clinical outcome of patients with early stage and metastatic non-small cell lung cancer (NSCLCa) harboring high genomic scarring score (GSS)Panteleimon Konstantoulakis, Georgia Christopoulou, Apostolos Klinakis, Katerina Tsilingiri et al.
- 3820Concordance analyses of a rapid, targeted, and comprehensive genomic profiling panel for the detection of guideline-recommended biomarkers in non-small cell lung cancerAmanda Williamson, Hardik Parikh, Jon Williams, Jie An et al.
- 2984In situ and functional analysis of Integrin-alpha 5 reveals its role in tumor progression in non-small cell lung cancerMirei Ka, Takahiro Ando, Munetoshi Hinata, Kousuke Watanabe et al.
- 469Quaratusugene ozeplasmid mediated TUSC2 upregulation in EML4-ALK bearing non-small cell lung carcinoma induces apoptosis and is highly effective in preclinical studies.Ananya Banerjee, Neeke Busette, Xu Cheng, Kerslee Kohagen et al.
- 7934IL-24 engineered mesenchymal stem cells as a novel therapeutic strategy to remodel the tumor microenvironment in non-small cell lung cancerYuting Zhang, Yuxuan Zhang, Sai Fung Yeung, Chi-Hang Wong et al.
- LB426Blockade of tumor-intrinsic TGF-beta signaling drives hyperprogression in small cell lung cancerAnish Thomas, Brett Schroeder, Chirayu Mohindroo, Anna-Lena Meinhardt et al.
- 6553A comprehensive analysis of HMGB1 as a biomarker for predicting immunotherapy efficacy in small cell lung cancerBohui Zhao, Chaoqi Zhang, Peng Wu, Dongyu Li et al.
- 5342Analysis of RNA expression of 47 cell surface proteins in real-world small cell lung cancer patients.Sana Parveen, Emma T. Corcoran, Sebastià Franch-Expósito, Prerna Jain et al.
- 4640Benefit of combining DLL3 targeted alpha therapy with standard of care in preclinical small cell lung cancer modelsHanan Babeker, Emma Cummins, Alex Mandel, Lily Li et al.
- 4546HER2- and TROP2-antibody-drug conjugates in small cell lung cancer cell lines and 3D culture: Efficacy and role of target expressionJenna Gray, Kavya Ramkumar, C. Allison Stewart, Runsheng Wang et al.
- 1335The ubiquitin E3 ligase SCFSkk2/Cks1complex: A critical node coupling cell cycle control, tumorigenesis, and lineage fidelity in small cell lung cancer (SCLC).Saumen Karan, Hongling Zhao, Yingjiao Xue, Xinrui Zhang et al.
- 7016Targeting sialylation promotes anti-tumor immunity in small cell lung cancerAlex D. Doan, Kelly Heard, Jackson Fatherree, Mallika Yalangi et al.
- 4730Construction of a prognostic model for small-cell lung cancer based on lipid metabolism related proteinsHaohua Zhu, Aijuan Yu, Huiyang Shi, Jingyu Lu et al.
- 2108Proteomic insights into metastatic small cell lung cancer using patient derived xenograft models.Sára Surguta, Laura Svajda, Zsolt Megyesfalvi, Bence Ferencz et al.
- 2652MGT-1142, an antibody-drug conjugate targeting a novel glycan for small-cell lung cancerSu-Yu Tsai, Maomao He, Ju-Mei Li, Ping Chao et al.
- 6381Extracellular vesicle-mediated co-delivery of FSL-1 and LY2157299 for immunotherapy of small-cell lung cancer liver metastases.Yue Huang, Amira Kazi, Rajesh Kumar, Kanak Parmar et al.
- 7024Simultaneous targeting of CHI3L1 and PD-1/PD-L1 axis to overcome drug resistance and immune tolerance of EGFR non-small cell lung cancer.Suchitra Kamle, Bing Ma, Brianna Pham, Isabella Fish et al.
- 5260DNMT3A -mutated tumor-infiltrating clonal hematopoiesis predicts immune checkpoint inhibitor response in advanced non-small cell lung cancerGeun-Ho Park, Cheolyong Joe, Hyemin Kim, Eunjoo Oh et al.
- 7217Homogeneity of mesothelin expression is tightly linked to its levels of expression in non-small cell lung cancerPhilipp Busch, Fiete Gehrisch, Nina Schraps, Katharina Möller et al.
- 4456Tumor Treating Fields (TTFields) potentiate antitumor and immune responses to standard immunochemotherapy in non-small cell lung cancer models.Boris Brant, Yiftah Barsheshet, Tali Voloshin, Tal Kan et al.
- 1448Deep learning integration of molecular and histopathological data for prognostic stratification in non small cell lung cancer.Sanddhya Jayabalan, Konstantinos Efthymiadis, Alexia Eliades, Kyriaki Papadopoulou et al.
- 7134Developing drug combinations with AMG 193, a novel MTA-cooperative PRMT5 inhibitor, using patient-derived xenograft models of MTAP -deleted non-small cell lung cancer and mesotheliomaFlorence T. Wu, Nhu-An Pham, Yu-Hui Wang, Ming Li et al.
- 1583Galectin9 targeted therapy for aiming cure in oncogenic driver alterations-positive non-small cell lung cancerTakanori Kondo, Toshiyuki Minami, Hidemi Kitai, Yoko Higashiguchi et al.
- 3732Time-series deep learning radiomics for predicting post-radiotherapy rib fractures in non-small cell lung cancerYijun Chen, Michael Farris, Ariel Choi, Nga Thi Thanh Nguyen et al.
- 6473Clonal consolidation and transcriptional re-programming define non-small cell lung cancers resistant to immune checkpoint inhibitorsNatalie Vokes, Arvind Ravi, Mark M. Awad, Patrick M. Forde et al.
- 3171Multitargeted kinase inhibitor LCI139 overcomes chemotherapy resistance in patient-derived non small cell lung cancer organoids by harnessing intrinsic and extrinsic apoptosisAnna Ivanina Foureau, Nadeem Wajih, Cody C. McHale, Hailey L. Dryden et al.
- 5568
- 196Lung inflammation accelerates tumor progression in a mouse model of oncogenic KRAS driven lung adenocarcinoma.Samantha A. Nelson, Jacob Kassama, Christina M. Cabana, Alexandria M. Jefferson et al.
- 5687Targeting KIFC1 induces anaphase catastrophe in small cell lung cancerMinemichi Toda, Natsuki Nakagawa, Masakatsu Tokunaga, Mirei Ka et al.
- 248Nesuparib (JPI-547), a dual tankyrase/PARP inhibitor, exhibits potent antitumor activity in small-cell lung cancer models by modulating Wnt and Hippo signaling pathways.Jun Kim, Joon-Hyung Lee, John Kim, Hyunju Cha et al.
- 5434Immune cell infiltration analysis of lung cancer based on proteomics.Ruoxian Zhang, Liangcheng Lyu
- 7778GS24-B047, a potential best-in-class DLL3-targeting T-cell engager with integrated costimulatory signal, for the treatment of small cell lung cancerZeng Qi, Fu Li, Zhiyu Cui, Hongmei Xie et al.
- LB266VBC229: A novel DLL3-targeting biparatopic T-cell engager-topoisomerase I inhibitor fusion molecule for depth and duration of response in small-cell lung cancerWei (Vivian) Wang, Xuekun Zhang, Kevin Yin, Man Xu et al.
- 1310Serial plasma comprehensive genomic profiling detects therapy resistance and guides management of metastatic non-small cell lung cancer.William Bowers, Michael Conroy, Jaime Wehr, Vivian V. Altiery De Jesus et al.
- 5366Prognostic value of tumor-informed circulating tumor DNA in non-small cell lung cancer after curative treatment: real-world cohort with long-term follow-up.Soyun Lim, Jisoo Lee, Julianne Jin, Anthony Wong et al.
- 3536Quantifying evolutionary dynamics and tumor heterogeneity in oncogene-addicted advanced non-small cell lung cancerLyns C. Etienne, Elizabeth E. Martin, Pinar Eser, Kiara Pontious et al.
- 5312Digital PCR-based plasma DNA methylationassayfor noninvasive molecular subtyping of small cell lung cancer: A prospective feasibility study.Jin-Soo Kim, Mi Young Kim, Jeemin Yim, Yun Young Lee et al.
- 4500
- 7385Cholesterol-associated immune cell dysfunction across lung cancer progressionJiwon Hwang, Ajay Tosh, Satyanarayana Rachagani
- 3528EED drives the small cell lung cancer neuroendocrine phenotype in lung cancer histological transformationYixiang Li, Yasmin N. Laimon, Hyeonseo Cho, Marina Vivero et al.
- 2694Dissecting the mechanisms of drug resistance development post neoadjuvant osimertinib treatment in EGFR-mutant non-small lung cancer.Su-Jin Choi, Jii Bum Lee, Hyuk Jee, Hyo Sup Shim et al.
- 449Albumin-based DLL3-targeted nano-immunoconjugates of SN38 preserve potency and demonstrate high-affinity DLL3 binding in small cell lung cancer.Mohamed Shanshal, Lin Yang, Liyi Geng, Wendy Nevala et al.
- 6845Using cell-type-specific nucleosome patterns to improve cell-free DNA fragmentation models in lung cancer.Brian Sun Liu, Mengran Zhang, Mohammad Shahrokh Esfahani
- 7945Whole-genome doubling induces chromosomal instability to shape the tumor-immune microenvironment and impair the response to immune checkpoint inhibitors in non-small cell lung cancerCheolyong Joe, Jinyong Kim, Hyemin Kim, Junsu Choe et al.
- 2836Tumor-derived extracellular vesicles as key messengers of radiotherapy-induced immunogenic cell death to sensitize small cell lung cancer to immunotherapyShanghai Liu, Kai Kang, Zhuoran Yao, Ren Luo et al.
- 6821The temporal dynamics and molecular impact of clonal hematopoiesis in non-small cell lung cancerAino-Maija Leppä, Oriol Pich, James R. Black, Maria Zagorulya et al.
- 6989RBM10 loss promotes KRAS -mutant non-small cell lung cancer immune tolerance and PD-1 inhibitor resistance via a non-canonical STING/ NF-κB axisMinh Truong Do, Teng Zhou, Mhd Yousuf Yassouf, Richard Lee et al.
- 3407Ensuring diverse in vitro lung cancer models: Development of alveolar epithelial cell lines, patient-derived xenografts, and lung adenocarcinoma cell lines from individuals of African ancestryKarla E. Gonzalez, Bianca Dal Bo, Chunli Yan, Donna Loza et al.
- 1975Genomic drivers of plasticity in transformed small cell lung cancer.Swanand Rakhade, Mamie Wang, Lena Morrill Gavarró, Emmanuel Spanos et al.
- 5007ELAVL3 post-transcriptionally regulation of the NOTCH2 signaling pathway shapes the plasticity of small cell lung cancerShuangsi Liao, Zichong Peng, Kai Kang, Shanghai Liu et al.
- LB193A novel DLL3-B7H3 bispecific dual-payload ADC, KHN928, demonstrates potent antitumor efficacy in small cell lung cancerLu Qi, Gang Lei, Pengfei Ren, Dan Zhang et al.
- 6857
- 5091Identification and validation of an explainable predictive model for early diagnosis of non-small cell lung cancer metastasis: A peripheral immune score based on integrative machine learningFan Xu, Bin Luo, Jianhui Tian, Zhenyang Cheng et al.
- 6161Ybx1 correlates with an immunosuppressive microenvironment in bone-metastatic lung adenocarcinomaYongsheng Wang, Liyun Miao
- 7858Machine learning predicts retinoblastoma (Rb) function in real-world small cell lung cancer patients.Sana Parveen, Neshatul Haque, Emma T. Corcoran, Sebastià Franch-Expósito et al.
- 7905Dihydroorotate dehydrogenase (DHODH) inhibition as a promising therapeutic strategy with synergistic targeting of ROR1 in small cell lung cancerBahareh Nourmohammadi, Ola A. Elgamal, Sandip Vibhute, Christopher C. Coss et al.
- 4127Inferring transcriptomic programs from circulating tumor DNA methylation signatures in small cell lung cancer using RRBS and EM-seqYuanxin Xi, Allison Stewart, Lixia Diao, Qi Wang et al.
- 3851Ultrasensitive ctDNA monitoring predicts early response of immunotherapy in recurrent metastatic non-small cell lung cancerKishen R. Patel, Bailiang Li, Charles W. Abbott, Cristina Naceur-Lombardelli et al.
- 1686Development of ZW418, a biparatopic PTK7-targeting antibody-drug conjugate incorporating a novel pan-RAS inhibitor payload for the treatment of non-small cell lung cancerLuying Yang, Alex Wu, Vincent Fung, Kaylee J. Wu et al.
- 5379Prognostic significance of STING expression in patients with resected lung adenocarcinoma.Jung-Jyh Hung, Ying-Shiun Kao
- SS03-01
- 4693The cancer testis antigen, HORMAD1, promotes genomic stability in lung adenocarcinomaRonnesha Johnson, Angelique Whitehurst, Anthony J. Davis, Luis Reza Herrera
- 4108
- 7197Molecular characteristics of MP0712, a clinical stage 212Pb-based Radio-DARPin candidate for targeted anti-DLL3 radiotherapy of small cell lung cancer (SCLC)Stefanie Riesenberg, Amal Saidi, Francesca Malvezzi, Aaron Schatzmann et al.