Indications / Non-small cell lung cancer · Breast cancer · Pancreatic cancer · Colorectal cancer · Acute myeloid leukemia · Chronic myeloid leukemia · Multiple myeloma · Glioblastoma · Glioma · Neuroblastoma · Medulloblastoma · Diffuse midline glioma (DIPG) · Ependymoma · Atypical teratoid rhabdoid tumour (AT/RT) · Childhood acute lymphoblastic leukemia · Ewing sarcoma · Osteosarcoma · Rhabdomyosarcoma
Osteosarcoma
The commonest bone cancer in teenagers; relapsed and metastatic disease remain hard to treat.
AACR Annual Meeting 2026
17–22 Apr 2026, San Diego · Cancer Research 86 (7_Supplement)
All 7,489 abstracts, including clinical trial (CT) and late-breaking (LB) abstracts, have Cancer Research supplement DOIs in Crossref.
Indexed in Crossref
37 abstracts matching osteosarcoma from the meeting's journal supplement, fetched live from Crossref 2026-11-12 06:39 UTC. This is a keyword search, not the complete abstract book.
- 4319Exploring oncolytic viral therapy to target osteosarcomaSumbul Khan, Therasa A. Higgins, Isabella S. Lofano, Payal Agarwal
- 3406Establishing an osteosarcoma organoid model reflecting the bone microenvironmentXin Li, Zhi Yang, Ba xuan Hoang, Bo Han
- 3059Targeting metabolic dependencies in MYC-driven osteosarcoma through Lp-PLA2 inhibitionKatherine Shelmidine, Juan Dou, Tajhal Patel, Jason Yustein
- 6125Osteosarcoma exploits macrophage VCAM1-VLA4 signaling axis to facilitate pulmonary metastasisDaniel Kingsley, Sung Hee Choi, Jay Myers, Alex Y. Huang
- 6671Actionable resistance mechanisms in osteosarcoma uncovered by the elucidate spatial biomarker platformGulpreet Kaur, Jason Weirather, James Perna, Sizun Jiang et al.
- 437Targeting RNA demethylase ALKBH5 with mefloquine enhances antitumor immunity and reduces osteosarcoma progression and metastasis.Victoria Chen Mai, Daisy Medina, Manjeet K. Rao
- 3777Spatial co-elevation of IGF1R and STMN1 associates with metastatic progression in osteosarcomaPiaopiao Luo, Xiaoqian Ma, Tairan Wang, Yiqing Wang et al.
- 1164Pacritinib mitigates doxorubicin resistance in osteosarcoma by inhibiting WNT/β-catenin, efflux proteins and receptor tyrosine kinase networkMarina Curcic, Sanjay Kumar Srivastava
- 5703Profiling osteosarcoma convergent evolution and molecular adaptations through patient-derived organoid drug-screeningKailee A. Rutherford, Jonathan N. Levi, Summer Norris, Alice Soragni
- 7666Comprehensive surfaceome profiling reveals tumor specific targets in osteosarcoma.Snehal D. Ganjave, Kevin K. Leung, Leanne C. Sayles, Alejandro Sweet-Cordero et al.
- LB284
- 5677GPX4-FTH1-ARNT signaling regulates iron efflux to suppress ferroptotic cell death and promote immune remodeling in osteosarcoma.Md Abdullah, Donghee Lee, Jong Hyuk Kim
- 2056Cross-species microRNA expression patterns identify potential therapeutic targets in osteosarcoma.Sophia C. Fernandes, Emma N. Vanderboon, Alicia Viloria-Petit, R. Darren Wood et al.
- 3542Evolving toward precision oncology: Leveraging collateral drug responses for personalized second-line osteosarcoma treatmentElizabeth Nowak, Jarrell Imamura, Arda Durmaz, Masahiro Hitomi et al.
- 5411Primary osteosarcoma of the short bones: A Surveillance, Epidemiology, and End Results Program (SEER) retrospective study.Jarrell Imamura, Elizabeth Nowak, Arda Durmaz, Jacob G. Scott et al.
- 2248Inhibition of the mitochondrial antioxidant response blocks ex vivo lung colonization in pediatric osteosarcoma.Elli Maria Tiliakou, Michael Lizardo, Yue-Zhou Huang, Taras Shyp et al.
- 7802cGAS-STING pathway agonist plus immune checkpoint inhibitor augments chemotherapy effectiveness in murine osteosarcoma modelsMayra L. Mendiola, Michele Doucet, Erin E. Resch, Brian H. Ladle
- 640Multiomic profiling reveals endothelial cell plasticity in metastatic osteosarcoma.Ying Wu, Julian Burks, Demond Williams, Carly Sayers et al.
- 2993Deciphering the key role of the glycosyltransferase GALNT14 in osteosarcoma tumorigenesisD. Isabel Petrescu, Tajhal D. Patel, Shoshana Leeds, Jeffrey Ritzenthaler et al.
- 3483LRRC15-Integrin β1 connection in osteosarcoma cells: Linking adhesion to invasionSanjit Mukherjee, Wei-Dong Chen, Lisa M. Jenkins, Yuelin Zhu et al.
- 7882Bridging data gaps in pediatric osteosarcoma: The first registry-based analysis of Puerto Rican casesMiaSara Pérez Salvá, Rocio Krystal Rivera-Valentin, Celinés Rodriguez, Liliana Marie Castro-Jimenez
- 6170Development and characterization of 3D osteosarcoma models recapitulating tumor heterogeneity and bone microenvironmentMargaux Chantoiseau, Pierre Khneisser, Birgit Geoerger, Nathalie Gaspar et al.
- 641Identifying vulnerabilities through an elucidation of the tumor-host interplay that drives osteosarcoma lung colonization.Fatemeh Yazarlou, Matthew Cannon, Yogesh Budhathoki, Amy C. Gross et al.
- 3933sB7-H3 as a prognostic biomarker in osteosarcoma: Insights into clinical outcomes.Lu Xie, Yuwei Zhao, Kunkun Sun, Yiyang Yu et al.
- 7870Targeting the MYC-SUMO axis with TAK-981 reverses immune suppression and restores antigen presentation in osteosarcomaBikesh Kumar Nirala, Jeffrey Ritzenthaler, Tajhal Patel, Taku Yamamichi et al.
- 1257Synergistic inhibition of PARP and ATM leads to unresolved DNA damage and cohesin-mediated collapse in pediatric osteosarcoma.Janeala Morsby, Sona Kocinsky, Estevez Prado Daniel, John Harper et al.
- 6621Riluzole as a dual targeted radiosensitizer for osteosarcoma: Targeting tumor cells and angiogenic vasculature to enhance single high dose radiotherapy efficacy.Pooja P. Rao, Adriana Haimovitz-Friedman, Charis Herbert, Syeda Maryam Azeem et al.
- 1428Single cell RNA-seq analysis of osteosarcoma reveals conserved and distinct ecosystems across sites and species.Yogesh Budhathoki, Matthew Cannon, Troy A. Mceachron, Anand G. Patel et al.
- 7874Dose-response efficacy of cell adhesion molecule 1 (CADM1)-GGFG-Exatecan vs CADM1-PEG3-VC-Exatecan in preclinical osteosarcoma modelsZhongting Zhang, Caterina Longo, Wendong Zhang, Yifei Wang et al.
- LB497Portraits of clonal landscape and mutational signature in primary tumors and matched lung metastatic model of osteosarcomaSylvester Jusu, Wengdong Zhang, Qi Wang, Xingzhi Song et al.
- 7883Surface CADM1 (Cell Adhesion Molecule 1) abundance predicts payload delivery and in-vitro efficacy of CADM1-GGFG-Exatecan ADC in osteosarcoma, aiding optimal candidate selectionCaterina Longo, Zhongting Zhang, Wendong Zhang, Yifei Wang et al.
- 7813Antitumor activity of a B7-H3 antibody-drug conjugate in osteosarcoma patient-derived and metastatic modelsWendong Zhang, Adil Bahadir, Zhongting Zhang, Yianhua Yi et al.
- 1151Targeting high risk osteosarcoma: MYC modulation alters metastasisEmily Seiden, Scott Sauer, Emma Hiscock, Nha Nhu Le et al.
- 2499Single-cell transcriptomic comparison of tumor before and after chemotherapy reveals therapeutic vulnerabilities in chemo-tolerant osteosarcoma cellsParisa Vahidi Ferdowsi, Kenny Yeo, Tiruneh Adane, Qian Wang et al.
- 6017BET inhibition potentiates salvage chemotherapy response through TXNIP upregulation in osteosarcomaKeiko E. Kreklau, Niknam Riyahi, Ryli E. Justice, M. Reza Saadatzadeh et al.
- 4024Dysregulated AKT signaling reprograms osteosarcoma to drive selective reliance on EP300Ian Delahunty, Stephanie Nance, Yang Zhang, Francois Lamoureux et al.
- 6483Convergent CDK4/6 and PI3K/mTOR pathway hyperactivation defines a targetable axis in osteosarcoma across RB1-proficient and RB1-deficient contextsLauren K. Stevens, M. Reza Saadatzadeh, Farinaz Barghi, Erika A. Dobrota et al.