Brigitte C Widemann
National Cancer Institute (NCI) · COG Phase I Consortium · National Cancer Institute, National Institutes of Health
Built from public records under this name as ClinicalTrials.gov spells it. A name can belong to more than one person, so each section says how its rows were tied to this name. No contact details are shown.
Trials
Studies that name Brigitte C Widemann as principal investigator, study chair or study director, newest first. Live from ClinicalTrials.gov, fetched 2026-11-11 22:57 UTC. Open this list on ClinicalTrials.gov
- N/ANCT06222203 · Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST)National Cancer Institute (NCI) · recruiting · Neurofibromatosis 1, Nerve Sheath Neoplasms · principal investigator
- N/ANCT04774289 · Incidence of Malignant Peripheral Nerve Sheath Tumor (MPNST) Development in Participants With Neurofibromatosis Type 1 (NF1) Receiving and Not Receiving Medical Therapies Directed at Plexiform Neurofibromas (PN)National Cancer Institute (NCI) · completed · Neurofibromatosis 1, Peripheral Nerve Neoplasms, Malignant · principal investigator
- Ph1/Ph2NCT04750928 · Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical NeurofibromasNational Cancer Institute (NCI) · recruiting · Neurofibromatosis 1 · principal investigator
- Ph2NCT03109301 · Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in People With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)National Cancer Institute (NCI) · withdrawn · Neoplasms, Nerve Tissue, Neurofibromatosis 1, Heredodegenerative Disorders, Nervous System · principal investigator
- Ph2NCT02407405 · MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform NeurofibromasNational Cancer Institute (NCI) · active not recruiting · Neurofibromatosis 1 (NF1), Plexiform Neurofibromas (PN) · principal investigator
- Ph1NCT02211768 · Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1National Cancer Institute (NCI) · completed · Neurofibromatosis, MPNST · principal investigator
- Ph2NCT02015065 · Phase II Trial of Vandetanib in Children and Adults With Wild-Type Gastrointestinal Stromal TumorsNational Cancer Institute (NCI) · completed · GIST · principal investigator
- Ph2NCT01661283 · SARC016: Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath TumorsSarcoma Alliance for Research through Collaboration · completed · Malignant Peripheral Nerve Sheath Tumors, MPNST, Sarcoma · principal investigator
- Ph1/Ph2NCT01610570 · Mithramycin for Children and Adults With Solid Tumors or Ewing SarcomaNational Cancer Institute (NCI) · terminated · Ewing Sarcoma, Sarcoma · principal investigator
- Ph1/Ph2NCT01445080 · Sorafenib in Treating Young Patients With Relapsed or Refractory Solid Tumors or LeukemiaNational Cancer Institute (NCI) · completed · Blastic Phase, Childhood Acute Promyelocytic Leukemia With PML-RARA, Childhood Chronic Myelogenous Leukemia, BCR-ABL1 Positive · principal investigator
- Ph1/Ph2NCT01362803 · AZD6244 Hydrogen Sulfate for Children With Nervous System TumorsNational Cancer Institute (NCI) · active not recruiting · Neurofibromatosis 1, Neurofibromatosis Type 1, NF1 · principal investigator
- Ph1NCT01259479 · Satraplatin in Children and Young Adults With Refractory Solid Tumors Including Brain TumorsNational Cancer Institute (NCI) · completed · Solid Tumors, Brain Tumors, Brain Metastases · principal investigator
- N/ANCT00924196 · Natural History Study of Patients With Neurofibromatosis Type INational Cancer Institute (NCI) · active not recruiting · Neurofibromatosis Type 1, Malignant Peripheral Nerve Sheath Tumor, Plexiform Neurofibroma · principal investigator
- Ph1NCT00727233 · Sorafenib to Treat Children and Young Adults With Neurofibromatosis Type 1 and Inoperable Plexiform NeurofibromasNational Cancer Institute (NCI) · completed · Neurofibromatosis Type I, Plexiform Neurofibroma · principal investigator
- Ph1/Ph2NCT00514046 · Vandetanib to Treat Children and Adolescents With Medullary Thyroid CancerNational Cancer Institute (NCI) · completed · Medullary Thyroid Carcinoma, Multiple Endocrine Neoplasia Type 2A, Multiple Endocrine Neoplasia Type 2B · principal investigator
- N/ANCT00340522 · Childhood Cancer and Plexiform Neurofibroma Tissue Microarray for Molecular Target Screening and Clinical Drug DevelopmentNational Cancer Institute (NCI) · completed · Cancer · principal investigator
- Ph1NCT00321581 · AZD2171 to Treat Children and Adolescents With Solid Tumors or Acute Myelogenous LeukemiaNational Cancer Institute (NCI) · completed · Refractory or Recurrent Solid Tumors, Acute Myelogenous Leukemia · principal investigator
- Ph2NCT00304083 · Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath TumorsSarcoma Alliance for Research through Collaboration · completed · Neurofibromatosis Type 1, Sarcoma · principal investigator
- Ph1NCT00253474 · PEG-Interferon Alfa-2b in Treating Young Patients With Plexiform NeurofibromaNational Institutes of Health Clinical Center (CC) · completed · Neoplasm of Uncertain Malignant Potential, Unspecified Childhood Solid Tumor, Protocol Specific · principal investigator
- Ph2NCT00076102 · Pirfenidone in Children and Young Adults With Neurofibromatosis Type I and Progressive Plexiform NeurofibromasNational Cancer Institute (NCI) · completed · Neurofibromatosis 1, Neurofibroma, Plexiform · principal investigator
- Ph1NCT00053937 · Pirfenidone in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform NeurofibromasNational Cancer Institute (NCI) · completed · Neurofibromatosis Type 1, Precancerous Condition · study chair
- N/ANCT00018967 · Carboxypeptidase-G2 in Treating Nervous System Toxic Effects in Patients Given an Overdose of Intrathecal MethotrexateNational Cancer Institute (NCI) · completed · Neurotoxicity, Unspecified Adult Solid Tumor, Protocol Specific, Unspecified Childhood Solid Tumor, Protocol Specific · study chair
- Ph1NCT00022451 · Tipifarnib in Treating Young Patients With Refractory LeukemiaNational Institutes of Health Clinical Center (CC) · completed · Leukemia · study chair
- N/ANCT00026780 · Eligibility Screening for a NCI Pediatric Oncology Branch Research StudyNational Cancer Institute (NCI) · completed · Ewing Sarcoma, Osteosarcoma, Neuroblastoma · principal investigator
- Ph1NCT00011414 · Phase I Trial of Tariquidar (XR9576) in Combination With Doxorubicin, Vinorelbine, or Docetaxel in Pediatric Patients With Solid TumorsNational Cancer Institute (NCI) · completed · Wilms' Tumor, Sarcoma, Adenaocortical Carcinoma · principal investigator
- N/ANCT00006435 · Study of Plexiform Neurofibromas in Neurofibromatosis Type 1National Cancer Institute (NCI) · completed · Plexiform Neurofibromas, NF1 · principal investigator
- N/ANCT00001686 · Evaluation, Treatment, and Natural History of Children and Young Adults With Cancer or Rare DiseasesNational Cancer Institute (NCI) · completed · Ewing's Sarcoma, Leukemia, Lymphoma · principal investigator
Grants
NIH projects from RePORTER, fetched 2026-11-11 22:57 UTC. A project is listed only when its grant number is on one of the trials above, or when the awardee institution matches an affiliation the registry gives for this name. 2 other NIH projects list an investigator with the same name at a different institution and are left out. Coverage is US federal funding only; UK and EU funders are not searched yet.
- MyPART: My Pediatric and Adult Rare Tumor Network - CuresZIABC011852 · NCI · DIVISION OF BASIC SCIENCES - NCI · fiscal years 2020 to 2025 · $827,438 awarded in 2025Same name and institution; not confirmed by an ID
- Therapies for patients with rare tumors and genetic tumor predispositionZIASC010354 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · fiscal years 2009 to 2025 · $2,831,748 awarded in 2025Same name and institution; not confirmed by an ID
- Therapy for NF1-Related Tumors and other Genetic Tumor Predisposition SyndromesZIABC010801 · NCI · DIVISION OF BASIC SCIENCES - NCI · fiscal years 2009 to 2020 · $1,468,055 awarded in 2020Same name and institution; not confirmed by an ID
- Clinical Development of Novel Drugs for Children with Refractory CancersZ01SC010354 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · fiscal years 2000 to 2008 · $142,432 awarded in 2008Same name and institution; not confirmed by an ID
- Development of Therapies for Neurofibromatosis Type 1 Related Tumors and other GZ01BC010801 · NCI · DIVISION OF BASIC SCIENCES - NCI · fiscal years 2007 to 2008 · $569,726 awarded in 2008Same name and institution; not confirmed by an ID
NIH grants that fund their trials
These grant numbers are on the registry records of the trials above. They fund the trial, often through a cooperative group or network, and their principal investigator is usually someone else.
- Children's Oncology Group Phase 1 / Pilot ConsortiumU01CA097452 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI SUSAN M. BLANEY · fiscal years 2002 to 2011Named on NCT01445080
Most cited trial papers
Clinical-trial papers with this author name, ranked by citations from NIH iCite, fetched 2026-11-11 22:57 UTC. The ranking covers the 200 most relevant of 60 PubMed records, and a shared surname and initials can bring in a namesake. All 60 on PubMed
- Selumetinib in Children with Inoperable Plexiform Neurofibromas.N Engl J Med · 2020570 citationsRCR 26.0
- Activity of Selumetinib in Neurofibromatosis Type 1-Related Plexiform Neurofibromas.N Engl J Med · 2016541 citationsRCR 17.0
- 169 citationsRCR 5.6
- 121 citationsRCR 6.6
- Efficacy and Biomarker Study of Bevacizumab for Hearing Loss Resulting From Neurofibromatosis Type 2-Associated Vestibular Schwannomas.J Clin Oncol · 2016116 citationsRCR 4.8
- Vandetanib in children and adolescents with multiple endocrine neoplasia type 2B associated medullary thyroid carcinoma.Clin Cancer Res · 2013111 citationsRCR 3.3
- 110 citationsRCR 2.4
- Sirolimus for progressive neurofibromatosis type 1-associated plexiform neurofibromas: a neurofibromatosis Clinical Trials Consortium phase II study.Neuro Oncol · 2015109 citationsRCR 3.5
- A phase I trial and pharmacokinetic study of sorafenib in children with refractory solid tumors or leukemias: a Children's Oncology Group Phase I Consortium report.Clin Cancer Res · 2012100 citationsRCR 2.7
- 94 citationsRCR 2.3