Carlos A Zarate
National Institute of Mental Health (NIMH) · Experimental Therapeutics and Pathophysiology Branch, DIRP, NIMH
Built from public records under this name as ClinicalTrials.gov spells it. A name can belong to more than one person, so each section says how its rows were tied to this name. No contact details are shown.
Registry trials as an overall official
22
all conditions, ClinicalTrials.gov
NIH grants tied to them
8
NIH RePORTER
Trial papers
111
PubMed author-name match
Trials
Studies that name Carlos A Zarate as principal investigator, study chair or study director, newest first. Live from ClinicalTrials.gov, fetched 2026-11-12 05:57 UTC. Open this list on ClinicalTrials.gov
- Ph2NCT06511908 · Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant DepressionNational Institute of Mental Health (NIMH) · recruiting · Suicide, Depressive Disorder, Treatment-Resistant, Ketamine · principal investigator
- Ph2NCT04821271 · Antidepressant Effects of TS-161 in Treatment-Resistant DepressionNational Institute of Mental Health (NIMH) · terminated · Major Depressive Disorder, Treatment-Resistant Depression, Depression · principal investigator
- Ph1NCT03973268 · Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major DepressionNational Institute of Mental Health (NIMH) · recruiting · Depression, Major Depressive Disorder, Major Depression · principal investigator
- N/ANCT03351764 · Development of Non-Invasive Brain Stimulation TechniquesNational Institute of Mental Health (NIMH) · completed · Normal Physiology · principal investigator
- N/ANCT03304665 · Recruitment and Characterization of Healthy Research Volunteers for NIMH Intramural StudiesNational Institute of Mental Health (NIMH) · recruiting · Healthy Volunteer · principal investigator
- N/ANCT03289923 · Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive EpisodesNational Institute of Mental Health (NIMH) · completed · Major Depressive Disorder · principal investigator
- Ph1NCT03065335 · Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive DisorderNational Institute of Mental Health (NIMH) · recruiting · Healthy Volunteer, Major Depressive Disorder, Depression · principal investigator
- Ph2NCT02543983 · Neurobiology of SuicideNational Institute of Mental Health (NIMH) · recruiting · Healthy Volunteers, Depression · principal investigator
- Ph2NCT02484456 · Antidepressant Effects of the Glycine Receptor Antagonist AV-101 (4-chlorokynurenine) in Major Depressive DisorderNational Institute of Mental Health (NIMH) · completed · Major Depression · principal investigator
- N/ANCT02363296 · Main Study: Influence on Plasticity of Brain Temperature Sub-Study: Phase Triggered Paired Associative Stimulation (PAS)National Institute of Mental Health (NIMH) · completed · Healthy Volunteers · principal investigator
- Ph1/Ph2NCT02049385 · Does Enhanced Glutamate Transporter Function Produce Antidepressant Effects in People With Major Depression?National Institute of Mental Health (NIMH) · terminated · Depression · principal investigator
- N/ANCT01313403 · Imaging Serotonin 5HT1A Receptors in Patients With Major Depressive DisorderNational Institute of Mental Health (NIMH) · withdrawn · Major Depression, Unipolar Depression, Depression · principal investigator
- Ph2NCT00986479 · This is a Study to Determine the Antidepressant Effects of AZD6765AstraZeneca · completed · Treatment Resistant Major Depressive Disorder · principal investigator
- N/ANCT00697268 · p11 Protein Levels in Patients With Major Depressive Disorder Treated With CitalopramNational Institute of Mental Health (NIMH) · completed · Depression · principal investigator
- Ph1NCT00472576 · Antidepressant Effects of NR2B in Major DepressionNational Institute of Mental Health (NIMH) · completed · Major Depression · principal investigator
- N/ANCT00024635 · Evaluation of Patients With Mood and Anxiety Disorders and Healthy VolunteersNational Institute of Mental Health (NIMH) · recruiting · Mood Disorders, Anxiety Disorders, Healthy Volunteers · principal investigator
- Ph1/Ph2NCT00088699 · Rapid Antidepressant Effects of Ketamine in Major DepressionNational Institute of Mental Health (NIMH) · completed · Depression, Mood Disorders, Major Depresssion · principal investigator
- Ph2NCT00086307 · Lexapro and Pramipexole and to Treat Major DepressionNational Institute of Mental Health (NIMH) · completed · Major Depression · principal investigator
- Ph2NCT00078715 · Rapid Antidepressant Effects of Yohimbine in Major DepressionNational Institute of Mental Health (NIMH) · completed · Depression, Involutional, Major Depresssion · principal investigator
- Ph2NCT00055575 · Cholinergic Modulation of Condition and Emotion in Mood Disorders: Functional Neuroimaging StudiesNational Institute of Mental Health (NIMH) · terminated · Mood Disorders, Healthy, Unipolar Depression · principal investigator
- Ph2NCT00054704 · Riluzole to Treat Depression in Bipolar DisorderNational Institute of Mental Health (NIMH) · terminated · Bipolar Disorder · principal investigator
- N/ANCT00001246 · Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy VolunteersNational Institute of Mental Health (NIMH) · completed · Attention Deficit Hyperactivity Disorder, Schizophrenia, Attention Deficit Disorder With Hyperactivity · principal investigator
Grants
NIH projects from RePORTER, fetched 2026-11-12 05:57 UTC. A project is listed only when its grant number is on one of the trials above, or when the awardee institution matches an affiliation the registry gives for this name. Coverage is US federal funding only; UK and EU funders are not searched yet.
- Glutamatergic Modulators for Rapid and Sustained Antidepressant EffectZIAMH002857 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · fiscal years 2010 to 2025 · $4,806,737 awarded in 2025Same name and institution; not confirmed by an ID
- Neurobiology and Target Validation of Novel Therapeutic Agents in Mood DisordersZIAMH002927 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · fiscal years 2010 to 2025 · $4,806,737 awarded in 2025Same name and institution; not confirmed by an ID
- Non-invasive Neuromodulation Unit (NNU)ZIAMH002955 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · fiscal years 2025 · $6,375,643 awarded in 2025Same name and institution; not confirmed by an ID
- Cholinergic Modulation of Cognition and Emotion in Mood DisordersZIAMH002813 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · fiscal years 2010 to 2014 · $718,694 awarded in 2014Same name and institution; not confirmed by an ID
- Efficacy of an Antiglutamatergic Agents in Treatment-Resistant DepressionZIAMH002828 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · fiscal years 2010 to 2014 · $239,564 awarded in 2014Same name and institution; not confirmed by an ID
- A pharmacologic strategy to bring about rapid (next day) antidepressants effectsZ01MH002853 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · fiscal years 2008 · $186,336 awarded in 2008Same name and institution; not confirmed by an ID
- Antidepressant Efficacy of an Antiglutamatergic Agent in Bipolar DepressionZ01MH002828 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · fiscal years 2008 · $232,920 awarded in 2008Same name and institution; not confirmed by an ID
- Comb Dopamine Agonist & Select Serotonin Reuptake Inhibitor f/Trtmt of DepressionZ01MH002856 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · fiscal years 2008 · $232,920 awarded in 2008Same name and institution; not confirmed by an ID
Most cited trial papers
Clinical-trial papers with this author name, ranked by citations from NIH iCite, fetched 2026-11-12 05:57 UTC. The ranking covers the 200 most relevant of 111 PubMed records, and a shared surname and initials can bring in a namesake. All 111 on PubMed
- A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression.Arch Gen Psychiatry · 20062,841 citationsRCR 78.4
- A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression.Arch Gen Psychiatry · 2010768 citationsRCR 24.7
- Replication of ketamine's antidepressant efficacy in bipolar depression: a randomized controlled add-on trial.Biol Psychiatry · 2012616 citationsRCR 21.8
- Rapid resolution of suicidal ideation after a single infusion of an N-methyl-D-aspartate antagonist in patients with treatment-resistant major depressive disorder.J Clin Psychiatry · 2010462 citationsRCR 14.8
- A double-blind, placebo-controlled study of memantine in the treatment of major depression.Am J Psychiatry · 2006337 citationsRCR 8.9
- Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapy.Arch Gen Psychiatry · 2002325 citationsRCR 10.9
- Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: a 47-week study.Am J Psychiatry · 2003253 citationsRCR 8.6
- An open-label trial of riluzole in patients with treatment-resistant major depression.Am J Psychiatry · 2004250 citationsRCR 6.5
- Pramipexole for bipolar II depression: a placebo-controlled proof of concept study.Biol Psychiatry · 2004242 citationsRCR 7.3
- Course of improvement in depressive symptoms to a single intravenous infusion of ketamine vs add-on riluzole: results from a 4-week, double-blind, placebo-controlled study.Neuropsychopharmacology · 2012242 citationsRCR 8.5