James C Eisenach
Atrium Health Wake Forest Baptist · Wake Forest University Health Sciences
Built from public records under this name as ClinicalTrials.gov spells it. A name can belong to more than one person, so each section says how its rows were tied to this name. No contact details are shown.
Registry trials as an overall official
30
all conditions, ClinicalTrials.gov
NIH grants tied to them
12
1 more share only the name and are not shown
Trial papers
68
PubMed author-name match
Trials
Studies that name James C Eisenach as principal investigator, study chair or study director, newest first. Live from ClinicalTrials.gov, fetched 2026-11-12 10:20 UTC. Open this list on ClinicalTrials.gov
- Ph2NCT07053774 · Intranasal and Intravenous Oxytocin for Analgesia to Noxious Heat PainWake Forest University Health Sciences · completed · Pain, Acute · principal investigator
- Ph2NCT06651476 · A Randomized Controlled Trial to Test the Effects Oxytocin and Vibration Have on Heat Pain Threshold After UV-B BurnWake Forest University Health Sciences · completed · Sunburn · principal investigator
- Ph2NCT05929339 · Defining a PK and PD Model for Peripheral Analgesia After IV OxytocinWake Forest University Health Sciences · completed · Acute Pain, Chronic Pain, Healthy Volunteer · principal investigator
- Ph1NCT05672667 · A Pharmacokinetic Study of Intravenous and Intranasal Oxytocin in Healthy SubjectsWake Forest University Health Sciences · completed · Healthy Volunteer Study · principal investigator
- Ph2NCT05179421 · Dose Ranging Study of Intravenous Oxytocin for Analgesia to Heat PainWake Forest University Health Sciences · completed · Healthy Volunteer Study · principal investigator
- Ph2NCT04493229 · A Pilot Feasibility Study of IM OXT on Fear of Pain and Trust in Physical Therapist During OP Rehabilitation After TKAWake Forest University Health Sciences · withdrawn · Osteoarthritis, Knee · principal investigator
- Ph2NCT04435704 · Validate a Pharmacodynamic Model of Oxytocin for Peripheral Analgesic EffectsWake Forest University Health Sciences · withdrawn · Osteoarthritis, Knee · principal investigator
- Ph2NCT04433741 · Apply the PD Model of Peripheral Oxytocin Action to a Multimodal StimulusWake Forest University Health Sciences · withdrawn · Pain, Chronic · principal investigator
- Ph2NCT04431193 · Estimate Serum Oxytocin PD Range in the PeripheryWake Forest University Health Sciences · withdrawn · Osteoarthritis, Knee · principal investigator
- Ph2NCT04431206 · Generate a Pharmacodynamic Model of Oxytocin for Peripheral Analgesic EffectsWake Forest University Health Sciences · terminated · Osteoarthritis, Knee, Healthy · principal investigator
- Ph2NCT04429880 · A Study of Oxytocin PK After IV Administration in Healthy Subjects and Advanced Knee Arthritis SubjectsWake Forest University Health Sciences · withdrawn · Osteoarthritis, Knee · principal investigator
- Ph2NCT04427709 · Generate and Test the Reliability of a PD Model of OXT on Pupillary Hippus as a Measure of CNS ActivityWake Forest University Health Sciences · terminated · Chronic Pain, Osteoarthritis, Knee · principal investigator
- Ph2NCT04427540 · Oxytocin Pharmacokinetics After Intramuscular InjectionWake Forest University Health Sciences · withdrawn · Osteoarthritis, Knee · principal investigator
- Ph4NCT04105998 · Effects of Intramuscular (IM) Oxytocin on Pupil Diameter and Heart Rate Variability (HRV)Wake Forest University Health Sciences · completed · Chronic Pain Due to Injury · principal investigator
- Ph4NCT03935399 · Effects of Intramuscular Oxytocin on Sensory Function in Healthy Volunteers With Ultraviolet Burn Injury to the SkinWake Forest University Health Sciences · completed · Chronic Pain · principal investigator
- Ph2NCT03011307 · Efficacy of Intrathecal Oxytocin to Speed Recovery After Hip SurgeryWake Forest University Health Sciences · terminated · Postoperative Pain · principal investigator
- Ph4NCT02685735 · Predicting, Understanding and Speeding Recovery After TKAWake Forest University Health Sciences · terminated · Pain, Total Knee Replacement, Total Hip Replacement · principal investigator
- N/ANCT02628314 · Reliability of Pupil Response to Acute PainWake Forest University Health Sciences · terminated · Pain, Osteoarthritis · principal investigator
- Ph4NCT02155257 · Pain Expectations in Subjects With OsteoarthritisWake Forest University Health Sciences · completed · Osteoarthritis · principal investigator
- Ph2NCT02100956 · Efficacy of Intrathecal Oxytocin in Patients With Neuropathic PainWake Forest University Health Sciences · terminated · Neuropathic Pain · principal investigator
- Ph2NCT01996605 · Efficacy of Spinal Oxytocin in Healthy VolunteersWake Forest University Health Sciences · terminated · Healthy Volunteer Study · principal investigator
- N/ANCT01843517 · Endogenous Pain Facilitation and Inhibition in Postpartum WomenWake Forest University · completed · Pain Inhibition and Facilitation in Post Partum Women · principal investigator
- Ph4NCT01743976 · Donepezil Compared to Placebo in Patients With Chronic Neuropathic PainWake Forest University · terminated · Neuropathic Pain · principal investigator
- N/ANCT01390298 · Pain and Function After Orthopedic SurgeryWake Forest University · completed · Chronic Pain · principal investigator
- Ph2NCT00693160 · Effect of Spinal Ketorolac After Acute Opioid ExposureWake Forest University · terminated · Healthy · principal investigator
- Ph2NCT00621530 · Effect of Spinal Ketorolac on Mechanical Hypersensitivity After a Total Hip ReplacementWake Forest University · terminated · Hip Arthroplasty · principal investigator
- Ph4NCT00619983 · Three Way Interaction Between Gabapentin, Duloxetine, and Donepezil in Patients With Diabetic NeuropathyWake Forest University · terminated · Diabetic Neuropathic Pain, Chronic Low Back Pain · principal investigator
- Ph2NCT00349921 · Clonidine Versus Adenosine to Treat Neuropathic PainWake Forest University Health Sciences · completed · Pain · principal investigator
- Ph2NCT00350532 · Clonidine-induced Spinal Acetylcholine Release: Normal Volunteers vs. Neuropathic PainWake Forest University Health Sciences · completed · Pain · principal investigator
- Ph2NCT00349401 · Intrathecal Ketorolac in Patients With Intrathecal Morphine Dose EscalationWake Forest University Health Sciences · withdrawn · Pain · principal investigator
Grants
NIH projects from RePORTER, fetched 2026-11-12 10:20 UTC. A project is listed only when its grant number is on one of the trials above, or when the awardee institution matches an affiliation the registry gives for this name. 1 other NIH projects list an investigator with the same name at a different institution and are left out. Coverage is US federal funding only; UK and EU funders are not searched yet.
- Creating PK/PD models for oxytocin action in humans and bridging to intranasal deliveryP01NS119159 · NINDS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · fiscal years 2022 to 2026 · $600,628 awarded in 2026Grant number is on one of their registry trials
- Recovery from Pain and Disability after SurgeryP01GM113852 · NIGMS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · fiscal years 2016 to 2021 · $156,451 awarded in 2021Grant number is on one of their registry trials
- Receptor Selective Spinal AnalgesiaR37GM048085 · NIGMS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · fiscal years 2011 to 2020 · $366,910 awarded in 2020Grant number is on one of their registry trials
- Spinal Noradrenergic Sprouting after Nerve InjuryR01NS057594 · NINDS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · fiscal years 2008 to 2012 · $317,275 awarded in 2012Grant number is on one of their registry trials
- CLINICAL TRIAL: THREE WAY INTERACTION AMONG GABAPENTIN, DULOXETINE, AND DONEPEZIM01RR007122 · NCRR · WAKE FOREST UNIVERSITY HEALTH SCIENCES · fiscal years 1994 to 2010 · $6,923 awarded in 2010Same name and institution; not confirmed by an ID
- Receptor Selective Spinal AnalgesiaR01GM048085 · NIGMS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · fiscal years 1992 to 2010 · $356,447 awarded in 2010Same name and institution; not confirmed by an ID
- Alpha2-Adrenergic AnalgesiaR01GM035523 · NIGMS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · fiscal years 1991 to 2006 · $353,649 awarded in 2006Same name and institution; not confirmed by an ID
- Pharmacologic Plasticity in the Presence of PainP01NS041386 · NINDS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · fiscal years 2002 to 2006 · $1,158,290 awarded in 2006Grant number is on one of their registry trials
- SEX DIFFERENCES IN CHOLINERGIC MEDIATED ANALGESIAR01DA012367 · NIDA · WAKE FOREST UNIVERSITY · fiscal years 1998 · $211,775 awarded in 1998Same name and institution; not confirmed by an ID
- EPIDURAL CLONIDINE ANALGESIA IN OBSTETRICSR29GM035523 · NIGMS · WAKE FOREST UNIVERSITY · fiscal years 1987 to 1989 · $103,351 awarded in 1989Same name and institution; not confirmed by an ID
- PRIMATE MODEL OF VISCERAL PAIN; MORPHINE; ANALGESICS; BEHAVIOR; ENDOMETRIOSISS07RR005404 · NCRR · WAKE FOREST UNIVERSITY · fiscal years 1989Same name and institution; not confirmed by an ID
- EPIDURAL CLONIDINE ANALGESIA IN OBSTETRICSR23GM035523 · NIGMS · WAKE FOREST UNIVERSITY · fiscal years 1985 to 1986 · $41,489 awarded in 1986Same name and institution; not confirmed by an ID
Most cited trial papers
Clinical-trial papers with this author name, ranked by citations from NIH iCite, fetched 2026-11-12 10:20 UTC. The ranking covers the 200 most relevant of 68 PubMed records, and a shared surname and initials can bring in a namesake. All 68 on PubMed
- Epidural clonidine analgesia for intractable cancer pain. The Epidural Clonidine Study Group.Pain · 1995307 citationsRCR 12.1
- Phase I safety assessment of intrathecal neostigmine methylsulfate in humans.Anesthesiology · 1995200 citationsRCR 9.1
- Epidural clonidine treatment for refractory reflex sympathetic dystrophy.Anesthesiology · 1993165 citationsRCR 7.4
- Intravenous remifentanil produces withdrawal hyperalgesia in volunteers with capsaicin-induced hyperalgesia.Anesth Analg · 2003137 citationsRCR 4.6
- Gabapentin activates spinal noradrenergic activity in rats and humans and reduces hypersensitivity after surgery.Anesthesiology · 2007126 citationsRCR 4.2
- Epidural clonidine analgesia after cesarean section.Anesthesiology · 1990105 citationsRCR 5.2
- Intrathecal sufentanil compared to epidural bupivacaine for labor analgesia.Anesthesiology · 1994103 citationsRCR 6.8
- A cholinergic interaction in alpha 2 adrenoceptor-mediated antinociception in sheep.J Pharmacol Exp Ther · 199396 citationsRCR 4.7
- Interaction between intrathecal neostigmine and epidural clonidine in human volunteers.Anesthesiology · 199693 citationsRCR 3.9
- Patient-controlled epidural analgesia during labor: a comparison of three solutions with a continuous infusion control.Anesthesiology · 199089 citationsRCR 7.8