Swee Lay Thein, M.D.

Trials

Studies that name Swee Lay Thein, M.D. as principal investigator, study chair or study director, newest first. Live from ClinicalTrials.gov, fetched 2026-11-12 06:35 UTC. Open this list on ClinicalTrials.gov

• Ph1
  NCT07566494 · Escalating Doses of VAS-101 in Subjects With Stable Sickle Cell Disease

  National Heart, Lung, and Blood Institute (NHLBI) · recruiting · Sickle Cell Disease, Hemolytic Anemia · principal investigator
• Ph1
  NCT05904093 · Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease

  National Heart, Lung, and Blood Institute (NHLBI) · recruiting · Sickle Cell Disorders, Sickle Cell Disease, Hemoglobin S · principal investigator
• N/A
  NCT05675436 · Investigating the Mechanistic Effects of Mitapivat in Subjects With Sickle Cell Disease

  National Heart, Lung, and Blood Institute (NHLBI) · active not recruiting · Sickle Cell Anemia, Sickle Cell Thalassemia, Sickle Cell Pain · principal investigator
• N/A
  NCT05604547 · Exploring Near Infrared Spectroscopy (NIRS) Technologies for Assessment of Muscle Physiology, Tissue Oxygenation, and Blood Flow in Patients With Sickle Cell Disease (SCD)

  National Heart, Lung, and Blood Institute (NHLBI) · completed · SCD · principal investigator
• Ph1/Ph2
  NCT04610866 · Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects With Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of Mitapivat

  National Heart, Lung, and Blood Institute (NHLBI) · active not recruiting · Sickle Cell Disease, Hemolytic Anemia · principal investigator
• Early Ph1
  NCT04000165 · A Dose-Finding Study of AG-348 in Sickle Cell Disease

  National Institutes of Health Clinical Center (CC) · completed · Sickle Cell Disease · principal investigator
• N/A
  NCT03685721 · Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell Disease

  National Heart, Lung, and Blood Institute (NHLBI) · recruiting · Sickle Cell, PKLR Variants, Adenosine Triphosphate Activities · principal investigator
• N/A
  NCT03572036 · Phosphodiesterase Type-5 Inhibitor Therapy in Sickle Cell People With Pulmonary Hypertension

  National Heart, Lung, and Blood Institute (NHLBI) · completed · Pulmonary Hypertension, Sickle Cell Disease · principal investigator
• N/A
  NCT03049475 · Pathophysiology of Acute Pain in Patients With Sickle Cell Disease

  National Heart, Lung, and Blood Institute (NHLBI) · completed · Sickle Cell Disease · principal investigator
• N/A
  NCT01441141 · Genetics and Pain Severity in Sickle Cell Disease

  National Heart, Lung, and Blood Institute (NHLBI) · completed · Genotype, Pain, Genetic Variation · principal investigator
• N/A
  NCT00367523 · Pulmonary Hypertension in Patients With Sickle Cell Disease in Nigeria

  National Heart, Lung, and Blood Institute (NHLBI) · completed · Secondary Pulmonary Arterial Hypertension, Sickle Cell Disease, Pulmonary Hypertension · principal investigator
• N/A
  NCT00081523 · Natural History of Sickle Cell Disease

  National Heart, Lung, and Blood Institute (NHLBI) · recruiting · Pain Crisis · principal investigator
• N/A
  NCT00047996 · Blood Collection for Research Related to Certain Diseases Involving Blood Vessels

  National Heart, Lung, and Blood Institute (NHLBI) · enrolling by invitation · Sickle Cell Disease · principal investigator
• N/A
  NCT00011648 · Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia

  National Heart, Lung, and Blood Institute (NHLBI) · completed · Pulmonary Hypertension, Sickle Cell Anemia, Sickle Cell Disease · principal investigator

Grants

NIH projects from RePORTER, fetched 2026-11-12 06:35 UTC. A project is listed only when its grant number is on one of the trials above, or when the awardee institution matches an affiliation the registry gives for this name. Coverage is US federal funding only; UK and EU funders are not searched yet.

No NIH project could be tied to this name by a shared trial or a matching institution.