Wells Messersmith
University of Colorado, Denver · Anschutz Cancer Pavilion · University of Colorado Cancer Center - Anschutz Cancer Pavilion
Built from public records under this name as ClinicalTrials.gov spells it. A name can belong to more than one person, so each section says how its rows were tied to this name. No contact details are shown.
Trials
Studies that name Wells Messersmith as principal investigator, study chair or study director, newest first. Live from ClinicalTrials.gov, fetched 2026-11-11 18:41 UTC. Open this list on ClinicalTrials.gov
- Ph2NCT05167409 · Study of Evorpacept (ALX148) With Cetuximab and Pembrolizumab for Refractory Microsatellite Stable Metastatic Colorectal CancerUniversity of Colorado, Denver · terminated · Microsatellite Stable Metastatic Colorectal Cancer · principal investigator
- Ph3NCT03781154 · Predictors of Physical Activity Maintenance in Colorectal Cancer SurvivorsUniversity of Colorado, Denver · completed · Colorectal Cancer · principal investigator
- Ph2NCT03542877 · Investigating Cabozantinib in Patients With Refractory Metastatic Colorectal CancerAcademic Thoracic Oncology Medical Investigators Consortium · completed · Colorectal Cancer · principal investigator
- Ph2NCT03038477 · A Study of Durvalumab in Patients With BR PDA Following Neoadjuvant Therapy and Successful Surgical ResectionUniversity of Colorado, Denver · withdrawn · Pancreatic Cancer · principal investigator
- N/ANCT02955446 · Compassionate Use Protocol for PF-03084014 in Patients With Advanced Solid Tumor MalignanciesUniversity of Colorado, Denver · no longer available · Neoplasm, Desmoid Tumor · principal investigator
- Ph2NCT02723331 · Perioperative Therapy for Resectable and Borderline-Resectable Pancreatic Adenocarcinoma With Molecular CorrelatesAcademic Thoracic Oncology Medical Investigators Consortium · completed · Pancreatic Cancer, Pancreatic Adenocarcinoma, Pancreas Ductal Adenocarcinoma · principal investigator
- Ph3NCT01360853 · Gemcitabine and ON 01910.Na in Previously Untreated Metastatic Pancreatic CancerTraws Pharma, Inc. · completed · Metastatic Pancreatic Adenocarcinoma · study chair
- Ph2NCT01232829 · Gamma Secretase Inhibitor RO4929097 in Previously Treated Metastatic Pancreas CancerNational Cancer Institute (NCI) · completed · Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, Stage IV Pancreatic Cancer · principal investigator
- Ph1/Ph2NCT00816777 · Chemoembolization, Irinotecan Bead, Second Line Chemotherapy Treatment of Unresectable Metastatic Colorectal CancerGeneric Devices Consulting, Inc. · terminated · Unresectable Metastatic Colo-rectal Cancer · principal investigator
- Ph2NCT00735917 · Saracatinib in Treating Patients With Previously Treated Metastatic Pancreatic CancerNational Cancer Institute (NCI) · completed · Adenocarcinoma of the Pancreas, Recurrent Pancreatic Cancer, Stage IV Pancreatic Cancer · principal investigator
- Ph2NCT00303927 · Capecitabine as Second-Line Therapy in Treating Patients With Stage IV Pancreatic Cancer Who Have the Thymidylate Synthase GeneSidney Kimmel Comprehensive Cancer Center at Johns Hopkins · completed · Pancreatic Cancer · study chair
- Ph1NCT00134069 · Sorafenib, Cetuximab, and Irinotecan in Treating Patients With Advanced or Metastatic Colorectal CancerNational Cancer Institute (NCI) · completed · Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage III Colon Cancer · principal investigator
- Ph1NCT00060411 · A Phase I, Pharmacological, and Biological Study of OSI-774 in Combination With FOLFOX 4 (5-FU, Leucovorin, and Oxaliplatin) and Bevacizumab (Avastin) in Patients With Advanced Colorectal CancerNational Cancer Institute (NCI) · completed · Mucinous Adenocarcinoma of the Colon, Mucinous Adenocarcinoma of the Rectum, Recurrent Colon Cancer · principal investigator
Grants
NIH projects from RePORTER, fetched 2026-11-11 18:41 UTC. A project is listed only when its grant number is on one of the trials above, or when the awardee institution matches an affiliation the registry gives for this name. Coverage is US federal funding only; UK and EU funders are not searched yet.
- The Johns Hopkins Translational Science Team and Consortium for ETCTN StudiesUM1CA186691 · NCI · JOHNS HOPKINS UNIVERSITY · fiscal years 2020 to 2026 · $1,854,447 awarded in 2026Same name and institution; not confirmed by an ID
- Biomarker-Driven Src Inhibitor Studies in Colorectal Cancer PatientsR01CA152303 · NCI · UNIVERSITY OF COLORADO DENVER · fiscal years 2010 to 2014 · $298,713 awarded in 2014Same name and institution; not confirmed by an ID
- Evaluation of Oral EGFR Inhibitors in Colorectal CancerK23CA115500 · NCI · UNIVERSITY OF COLORADO DENVER · fiscal years 2005 to 2009 · $137,700 awarded in 2009Same name and institution; not confirmed by an ID
- Evaluation of Src Inhibition in Pancreas CancerR21CA135622 · NCI · UNIVERSITY OF COLORADO DENVER · fiscal years 2008 to 2009 · $314,341 awarded in 2009Same name and institution; not confirmed by an ID
- BAY 43-9006 IN COMBINATION WITH CETUXIMAB AND IRINOTECANM01RR000052 · NCRR · JOHNS HOPKINS UNIVERSITY · fiscal years 2007 · $38 awarded in 2007Same name and institution; not confirmed by an ID
- Evaluation of BAY43-9006/Cetuximab in Colorectal CancerR21CA117125 · NCI · UNIVERSITY OF COLORADO DENVER · fiscal years 2006 to 2007 · $246,308 awarded in 2007Grant number is on one of their registry trials
NIH grants that fund their trials
These grant numbers are on the registry records of the trials above. They fund the trial, often through a cooperative group or network, and their principal investigator is usually someone else.
- U01CA070095RePORTER returned no project for this number; it is shown as the registry gives it.
- Cancer Research Training and Education CoordinationP30CA046934 · NCI · UNIVERSITY OF COLORADO DENVER · PI James V Degregori · fiscal years 2020 to 2026Named on NCT01232829
- Pathology Research Shared ResourceP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI THOMAS J FLOTTE · fiscal years 2020 to 2026Named on NCT00735917
- Cancer Chemical and Structural BiologyP30CA006973 · NCI · JOHNS HOPKINS UNIVERSITY · PI James M. Berger · fiscal years 2020 to 2026Named on NCT00303927
Most cited trial papers
Clinical-trial papers with this author name, ranked by citations from NIH iCite, fetched 2026-11-11 18:41 UTC. The ranking covers the 200 most relevant of 76 PubMed records, and a shared surname and initials can bring in a namesake. All 76 on PubMed
- Safety, pharmacokinetic, pharmacodynamic, and efficacy data for the oral MEK inhibitor trametinib: a phase 1 dose-escalation trial.Lancet Oncol · 2012481 citationsRCR 11.6
- Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial.Lancet Oncol · 2012453 citationsRCR 11.4
- Combined BRAF and MEK Inhibition With Dabrafenib and Trametinib in BRAF V600-Mutant Colorectal Cancer.J Clin Oncol · 2015434 citationsRCR 11.6
- 366 citationsRCR 18.9
- Phase I Dose-Escalation Trial of MIW815 (ADU-S100), an Intratumoral STING Agonist, in Patients with Advanced/Metastatic Solid Tumors or Lymphomas.Clin Cancer Res · 2022366 citationsRCR 22.5
- Efficacy and Safety of Anti-Trop-2 Antibody Drug Conjugate Sacituzumab Govitecan (IMMU-132) in Heavily Pretreated Patients With Metastatic Triple-Negative Breast Cancer.J Clin Oncol · 2017349 citationsRCR 10.7
- Phase I study of RO4929097, a gamma secretase inhibitor of Notch signaling, in patients with refractory metastatic or locally advanced solid tumors.J Clin Oncol · 2012228 citationsRCR 5.5
- 216 citationsRCR 6.6
- A First-in-Human Phase I Study of the Anticancer Stem Cell Agent Ipafricept (OMP-54F28), a Decoy Receptor for Wnt Ligands, in Patients with Advanced Solid Tumors.Clin Cancer Res · 2017187 citationsRCR 6.0
- A Phase I, dose-finding study in patients with advanced solid malignancies of the oral γ-secretase inhibitor PF-03084014.Clin Cancer Res · 2015184 citationsRCR 5.0