Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 06:04 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Open-Label Extension Of Intravenous Mepolizumab In Patients With Hypereosinophilic Syndrome
NCT00097370 · GlaxoSmithKline · PHASE3 · terminated · last registry update 2017-07-07 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Study terminated by sponsor (29 Sep 2010). Subjects eligible to continue mepolizumab treatment were transferred into the compassionate use program (MHE104317)” | – | Registry record, GlaxoSmithKline |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against IL5 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2018-06-29Results posted on the registry: GlaxoSmithKline, Mepolizumab (NCT03099096)
- 2018-06-19Phase 3 first posted: GlaxoSmithKline, Mepolizumab 100 milligrams + Placebo (NCT03562195)
- 2018-05-22Results posted on the registry: GlaxoSmithKline, Mepolizumab (NCT01691859)
- 2018-05-02Results posted on the registry: GlaxoSmithKline, Mepolizumab + SOC (NCT02135692)
- 2018-04-06Results posted on the registry: GlaxoSmithKline, Mepolizumab + Placebo (NCT02105948)
- 2018-04-06Results posted on the registry: GlaxoSmithKline, Mepolizumab + Placebo (NCT02105961)
- 2018-01-31Results posted on the registry: GlaxoSmithKline, Mepolizumab 100mg SC + Albuterol/salbutamol MDIs (NCT02654145)
- 2018-01-31Results posted on the registry: GlaxoSmithKline, Mepolizumab (NCT03021304)
- 2018-01-26Results posted on the registry: GlaxoSmithKline, Mepolizumab + Placebo (NCT02020889)
- 2017-12-12Results posted on the registry: University of Wisconsin, Madison, mepolizumab (NCT00802438)
- 2017-11-29Results posted on the registry: GlaxoSmithKline, Mepolizumab (NCT02377427)
- 2017-10-10Phase 3 first posted: GlaxoSmithKline, Mepolizumab (NCT03306043)
- 2017-09-29Phase 3 first posted: GlaxoSmithKline, Mepolizumab + Prednisolone (NCT03298061)
- 2017-07-13Also stopped (terminated): Johannes Gutenberg University Mainz, Mepolizumab + Placebo (NCT02594332)
- 2017-06-01Results posted on the registry: National Institute of Allergy and Infectious Diseases (NIAID), Reslizumab + Diethylcarbamazine (NCT01111305)
- 2017-05-04Results posted on the registry: GlaxoSmithKline, Mepolizumab + Placebo (NCT02281318)
- 2017-04-04Phase 3 first posted: GlaxoSmithKline, Mepolizumab (NCT03099096)
- 2017-03-23Results posted on the registry: Ception Therapeutics, reslizumab (NCT00635089)
- 2017-03-22Results posted on the registry: Brigham and Women's Hospital, Mepolizumab (NCT00527566)
- 2017-03-21Phase 3 first posted: GlaxoSmithKline, Mepolizumab + Placebo (NCT03085797)
- 2017-02-14Phase 3 first posted: Teva Branded Pharmaceutical Products R&D, Inc., reslizumab (NCT03052725)
- 2017-01-13Phase 3 first posted: GlaxoSmithKline, Mepolizumab (NCT03021304)
- 2017-01-09Phase 3 first posted: GlaxoSmithKline, Lyophilized mepolizumab + Liquid mepolizumab (NCT03014674)
- 2016-09-02Results posted on the registry: Ception Therapeutics, Reslizumab (NCT00538434)
- 2016-07-19Phase 3 first posted: GlaxoSmithKline, Mepolizumab 300 mg + Placebo matching mepolizumab (NCT02836496)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision