Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 07:31 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Baclofen Effects on Smoking Urge and Withdrawal
NCT00257894 · VA Office of Research and Development · PHASE2 · terminated · last registry update 2015-11-04 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Enrollment was completed with insufficient sample size for publishable results” | – | Registry record, VA Office of Research and Development |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against GABBR1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2016-10-06Also stopped (withdrawn): University of Missouri-Columbia, baclofen, intrathecal (NCT01352611)
- 2016-09-08Also stopped (withdrawn): University of Pennsylvania, Baclofen ER + Placebo (NCT02003664)
- 2016-08-17Phase 3 first posted: RVL Pharmaceuticals, Inc., arbaclofen ER Tablets + Placebo for arbaclofen ER tablets (NCT02869425)
- 2016-07-15Results posted on the registry: University of Rochester, Amitriptyline + Baclofen (NCT02099006)
- 2016-05-19Also stopped (terminated): University of Medicine and Dentistry of New Jersey, Placebo + Sodium Oxybate (NCT00498485)
- 2016-05-13Also stopped (suspended): University of Liege, Baclofen + Placebo (NCT02529514)
- 2016-04-21Results posted on the registry: University of Medicine and Dentistry of New Jersey, Placebo + Sodium Oxybate (NCT00498485)
- 2016-03-30Phase 3 first posted: Nantes University Hospital, BACLOFEN + PLACEBO (NCT02723383)
- 2016-03-28Phase 3 first posted: Avadel, FT218 + Placebo (NCT02720744)
- 2016-02-08Results posted on the registry: Nathan Kline Institute for Psychiatric Research, Sodium Oxybate (NCT00594256)
- 2015-12-22Phase 3 first posted: Ramin Khatami, Sodium Oxybate + Placebo (NCT02637648)
- 2015-08-21Also stopped (terminated): Gonzalez-Heydrich, Joseph, M.D., R-baclofen (NCT01172509)
- 2015-07-14Phase 3 first posted: Walter Reed National Military Medical Center, a drug against GABBR1 (NCT02497066)
- 2015-06-09Results posted on the registry: VA Office of Research and Development, baclofen + placebo (NCT01008280)
- 2015-03-06Also stopped (withdrawn): Flowonix Medical, a drug against GABBR1 (NCT01051128)
- 2015-02-05Results posted on the registry: University of Virginia, Baclofen (NCT02298868)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision