Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 23:56 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Efficacy, Safety and Tolerability of E2007 in Levodopa Treated Parkinson's Disease Patients With Motor Fluctuations
NCT00360308 · Eisai Limited · PHASE3 · terminated · last registry update 2014-07-11 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Study stopped due to lack of efficacy.” | – | Registry record, Eisai Limited |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against GRIA4 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2015-06-08Results posted on the registry: Eisai Inc., E2007 (NCT00154063)
- 2015-06-02Results posted on the registry: Eisai Inc., E2007 (NCT00165789)
- 2015-04-28Phase 3 first posted: Eisai Co., Ltd., Perampanel (NCT02427607)
- 2015-04-28Also stopped (terminated): Boston Medical Center, Topiramate + Zonisamide (NCT00862563)
- 2015-04-07Results posted on the registry: Boston Medical Center, Topiramate + Zonisamide (NCT00862563)
- 2015-03-18Results posted on the registry: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Celecoxib (NCT00068770)
- 2015-03-18Also stopped (terminated): Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Celecoxib (NCT00068770)
- 2015-03-06Also stopped (withdrawn): University of California, San Francisco, topiramate + lactulose placebo pill (NCT00732108)
- 2015-03-02Phase 3 first posted: Hannover Medical School, Phenobarbital + Phenytoin (NCT02374567)
- 2015-02-23Results posted on the registry: Upsher-Smith Laboratories, USL255 (NCT01191086)
- 2015-02-23Results posted on the registry: Mayo Clinic, Phentermine-Topiramate ER + Placebo (NCT01834404)
- 2015-02-10Also stopped (withdrawn): Eisai Inc., Perampanel + Placebo (NCT02220972)
- 2014-12-22Results posted on the registry: Bial - Portela C S.A., BIA 2-093 + Topamax (NCT02283814)
- 2014-10-24Phase 3 first posted: Assistance Publique - Hôpitaux de Paris, Topiramate + Placebo (NCT02273804)
- 2014-10-13Results posted on the registry: Cady, Roger, M.D., onabotulinumtoxinA + Topiramate (NCT01700387)
- 2014-09-01Results posted on the registry: Kyle Kampman, Topiramate + placebo (NCT00167245)
- 2014-08-29Results posted on the registry: Merck Sharp & Dohme LLC, MK-8777 + Placebo (NCT00610441)
- 2014-08-26Results posted on the registry: Federal University of São Paulo, Topiramate + placebo control group (NCT00725920)
- 2014-07-28Phase 3 first posted: Janssen Research & Development, LLC, Topiramate + Levetiracetam (NCT02201251)
- 2014-07-11Also stopped (terminated): Eisai Inc., E2007 (NCT00360412)
- 2014-07-09Also stopped (terminated): Eisai Inc., Perampanel (NCT01634360)
- 2014-07-02Results posted on the registry: Merck Sharp & Dohme LLC, MK-8777 + Placebo (NCT00610649)
- 2014-06-03Results posted on the registry: University of California, San Francisco, Topiramate (NCT01087736)
- 2014-05-07Results posted on the registry: Upsher-Smith Laboratories, USL255 + Placebo (NCT01142193)
- 2014-01-20Also stopped (terminated): University of Copenhagen, Topiramate 96 mg daily + Topiramate 192 mg daily (NCT02040311)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision