OncoSignal
Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 15:46 UTC. Every row links to its source record.

Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time

MONET1-MOtesanib NSCLC Efficacy and Tolerability Study

NCT00460317 · Amgen · PHASE3 · terminated · last registry update 2015-09-07 · Non-small cell lung cancer · Decision brief

No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.

What was said, and by whom

Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.

KindQuoteOur categorySource
Stated“Amgen discontinued the development of AMG706 because 20050201 did not meet its primary objective.”Open Targets' class: business administrativeRegistry record, Amgen

Also happening at the time. Not shown to be a cause.

Registry events on other trials of drugs against KIT in non-small cell lung cancer within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.

No results, stops or Phase 3 starts on the same target in that window.

What is not public

  • Internal portfolio and board discussions
  • Unpublished trial data and interim analyses
  • Terms of any partner or licence decision