Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 06:05 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Trial of Dextromethorphan in Rett Syndrome
NCT00593957 · Hugo W. Moser Research Institute at Kennedy Krieger, Inc. · PHASE2 · terminated · last registry update 2014-04-23 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Study changed to a placebo controlled trial of dextromethorphan” | – | Registry record, Hugo W. Moser Research Institute at Kennedy Krieger, Inc. |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against SIGMAR1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2015-03-31Results posted on the registry: Taichung Veterans General Hospital, Dextromethorphan hydrobromide (NCT02368093)
- 2014-12-23Also stopped (withdrawn): Children's National Research Institute, Dextromethorphan + Codeine (NCT00513864)
- 2014-12-04Phase 3 first posted: Emergency NGO Onlus, Best Supportive Care + Best Supportive Care + Amiodarone (NCT02307591)
- 2014-09-04Results posted on the registry: Mclean Hospital, Talwin Nx (NCT00125931)
- 2014-08-22Results posted on the registry: Repros Therapeutics Inc., Proellex + CYP1A2 probe (NCT00741468)
- 2014-08-21Results posted on the registry: Mclean Hospital, Pentazocine + Lorazepam (NCT00431184)
- 2014-08-08Phase 3 first posted: Duke University, Dextromethophan (NCT02212275)
- 2014-06-27Results posted on the registry: Bristol-Myers Squibb, Caffeine + Losartan (NCT01766050)
- 2014-03-04Results posted on the registry: Aegerion Pharmaceuticals, Inc., atorvastatin + simvastatin (NCT00359281)
- 2013-07-10Results posted on the registry: Avanir Pharmaceuticals, dextromethorphan hydrobromide 20 mg and quinidine sulfate 10 mg + dextromethorphan hydrobromide 30 mg and quinidine sulfate 10 mg (NCT00573443)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision