Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 16:02 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Sunitinib Malate to Treat Advanced Eye Disease in Patients With Von Hippel-Lindau Syndrome
NCT00673816 · National Eye Institute (NEI) · PHASE1/PHASE2 · terminated · last registry update 2024-01-05 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Inability to recruit and adequate number of participants” | – | Registry record, National Eye Institute (NEI) |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against CSF1R within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2024-12-30Results posted on the registry: Daiichi Sankyo, Pexidartinib (NCT04526704)
- 2024-12-10Phase 3 first posted: Sun Yat-sen University, axitinib ± immune checkpoint inhibitors (ICIs), lenvatinib ± ICIs, cabozantinib ± ICIs, sunitinib and pazopanib (NCT06726421)
- 2024-11-27Results posted on the registry: Syndax Pharmaceuticals, axatilimab (NCT03604692)
- 2024-10-29Results posted on the registry: Pfizer, Avelumab (MSB0010718C) + Axitinib (AG-013736) (NCT02684006)
- 2024-10-17Results posted on the registry: University Health Network, Toronto, Sunitinib (NCT00843037)
- 2024-10-10Results posted on the registry: Syndax Pharmaceuticals, Axatilimab (NCT04710576)
- 2024-09-19Phase 3 first posted: Incyte Corporation, INCA034176 + Placebo (NCT06585774)
- 2024-09-19Results posted on the registry: National Cancer Institute (NCI), Cediranib + Sunitinib (NCT01391962)
- 2024-09-19Results posted on the registry: M.D. Anderson Cancer Center, Quizartinib + Venetoclax (NCT03735875)
- 2024-09-19Also stopped (terminated): M.D. Anderson Cancer Center, Quizartinib + Venetoclax (NCT03735875)
- 2024-08-29Phase 3 first posted: Daiichi Sankyo, Quizartinib + Placebo (NCT06578247)
- 2024-08-09Results posted on the registry: Ludwig-Maximilians - University of Munich, Pazopanib + Placebo (for Pazopanib) (NCT02207309)
- 2024-08-09Also stopped (terminated): Ludwig-Maximilians - University of Munich, Pazopanib + Placebo (for Pazopanib) (NCT02207309)
- 2024-07-23Results posted on the registry: Bristol-Myers Squibb, Cabiralizumab + Nab-paclitaxel (NCT03336216)
- 2024-06-27Also stopped (terminated): M.D. Anderson Cancer Center, SU011248 (NCT00330564)
- 2024-06-25Also stopped (terminated): Brown University, Abemaciclib + Sunitinib (NCT03905889)
- 2024-06-13Results posted on the registry: ImmunityBio, Inc., Aldoxorubicin + Investigator's Choice Treatment (Darcabazine, Pazopanib, Gemcitabine + Docetaxel, Doxorubicin, Ifosfamide) (NCT02049905)
- 2024-06-05Results posted on the registry: Theseus Pharmaceuticals, THE-630 (NCT05160168)
- 2024-06-05Also stopped (terminated): Theseus Pharmaceuticals, THE-630 (NCT05160168)
- 2024-05-16Results posted on the registry: Washington University School of Medicine, Paclitaxel + Carboplatin (NCT04331067)
- 2024-03-13Results posted on the registry: University of Washington, Sirolimus Albumin-bound Nanoparticles + Pazopanib hydrochloride (NCT03660930)
- 2024-03-13Also stopped (terminated): M.D. Anderson Cancer Center, Bevacizumab + Emactuzumab (NCT02923739)
- 2024-03-04Also stopped (terminated): OHSU Knight Cancer Institute, Abemaciclib + Abiraterone (NCT03878524)
- 2024-02-28Results posted on the registry: M.D. Anderson Cancer Center, Azacitidine + Cytarabine (NCT01892371)
- 2024-02-23Phase 3 first posted: Gossamer Bio USA, Inc., Seralutinib (NCT06274801)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision