Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 02:55 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Ursodeoxycholic Acid Plus Budesonide Versus Ursodeoxycholic Acid Alone in Primary Biliary Cirrhosis (PBC)
NCT00746486 · Dr. Falk Pharma GmbH · PHASE3 · terminated · last registry update 2020-01-28 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Study stopped based on the recommendation of the IDMC after a planned Interim Analysis” | – | Registry record, Dr. Falk Pharma GmbH |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against NR3C1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2020-12-23Results posted on the registry: OHSU Knight Cancer Institute, Cabazitaxel + Enzalutamide (NCT02522715)
- 2020-08-28Phase 3 first posted: National Cancer Institute (NCI), Blinatumomab + Cyclophosphamide (NCT04530565)
- 2020-07-14Phase 3 first posted: Cristcot HCA LLC, Twice daily 90 mg hydrocortisone acetate suppository administered with Sephure applicator + Once daily 90 mg hydrocortisone acetate or placebo suppository administered with Sephure applicator (NCT04469686)
- 2020-05-11Phase 3 first posted: University of Oxford, Lopinavir-Ritonavir + Corticosteroid (NCT04381936)
- 2020-04-24Phase 3 first posted: University Hospital, Tours, Prednisone + Hydrocortisone (NCT04359511)
- 2020-03-03Phase 3 first posted: Children's Oncology Group, Asparaginase Erwinia chrysanthemi + Cytarabine (NCT04293562)
- 2019-09-13Results posted on the registry: Neurocrine UK Limited, Infacort® (NCT02733367)
- 2019-09-04Results posted on the registry: Neurocrine UK Limited, Chronocort® + standard glucocorticoid therapy (NCT02716818)
- 2019-06-20Results posted on the registry: National Cancer Institute (NCI), Asparaginase + Cyclophosphamide (NCT00408005)
- 2019-06-13Phase 3 first posted: National Cancer Institute (NCI), Cyclophosphamide + Doxorubicin Hydrochloride (NCT03984448)
- 2019-05-22Phase 3 first posted: Children's Oncology Group, Blinatumomab + Calaspargase Pegol (NCT03959085)
- 2019-04-16Phase 3 first posted: National Cancer Institute (NCI), Asparaginase Erwinia chrysanthemi + Blinatumomab (NCT03914625)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision