Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 07:52 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Mesenchymal Stem Cells Under Basiliximab/Low Dose RATG to Induce Renal Transplant Tolerance
NCT00752479 · Mario Negri Institute for Pharmacological Research · PHASE1/PHASE2 · terminated · last registry update 2023-12-04 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Necessity of major revision of the protocol” | – | Registry record, Mario Negri Institute for Pharmacological Research |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against RAF1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2024-11-21Also stopped (withdrawn): City of Hope Medical Center, Balstilimab + Botensilimab (NCT06575725)
- 2024-11-20Also stopped (terminated): Astellas Pharma Inc, OSI-906 + Placebo (NCT01101906)
- 2024-10-15Results posted on the registry: EpicentRx, Inc., RRx-001 + Regorafenib (NCT02096354)
- 2024-10-04Results posted on the registry: Asan Medical Center, Regorafenib (NCT02175095)
- 2024-09-27Results posted on the registry: Academic and Community Cancer Research United, Cetuximab + Irinotecan (NCT04117945)
- 2024-09-25Results posted on the registry: Hutchison Medipharma Limited, Fruquintinib (HMPL-013) (NCT03251378)
- 2024-09-19Also stopped (terminated): Taiho Oncology, Inc., TAC-101 + Placebo (NCT00687596)
- 2024-07-23Results posted on the registry: Bayer, Regorafenib, (Stivarga, BAY73-4506) + Nivolumab (Opdivo) (NCT04704154)
- 2024-06-26Results posted on the registry: Wake Forest University Health Sciences, Regorafenib (NCT02581059)
- 2024-06-26Also stopped (terminated): Wake Forest University Health Sciences, Regorafenib (NCT02581059)
- 2024-06-05Results posted on the registry: Theseus Pharmaceuticals, THE-630 (NCT05160168)
- 2024-06-05Also stopped (terminated): Theseus Pharmaceuticals, THE-630 (NCT05160168)
- 2024-05-29Results posted on the registry: Roswell Park Cancer Institute, Pembrolizumab + Sorafenib Tosylate (NCT03211416)
- 2024-05-21Results posted on the registry: Academic and Community Cancer Research United, Panitumumab + Regorafenib (NCT03992456)
- 2024-04-29Also stopped (withdrawn): M.D. Anderson Cancer Center, Regorafenib + XmAb20717 (NCT05900648)
- 2024-04-09Results posted on the registry: Merck Sharp & Dohme LLC, pembrolizumab + lenvatinib (NCT04776148)
- 2024-04-03Phase 3 first posted: Erasca, Inc., Naporafenib + Dacarbazine (NCT06346067)
- 2024-04-02Results posted on the registry: Bayer, BAY73-4506 (Regorafenib, Stivarga) (NCT03890731)
- 2024-03-19Results posted on the registry: M.D. Anderson Cancer Center, Clofarabine + Cytarabine (NCT02135874)
- 2024-03-05Also stopped (terminated): Millennium Pharmaceuticals, Inc., TAK-580 + TAK-202 (NCT02723006)
- 2024-03-04Also stopped (terminated): OHSU Knight Cancer Institute, Abemaciclib + Abiraterone (NCT03878524)
- 2024-02-29Phase 3 first posted: The Second Affiliated Hospital of Kunming Medical University, a drug against RAF1 (NCT06285136)
- 2024-02-23Results posted on the registry: Federation Francophone de Cancerologie Digestive, Regorafenib 160 mg (NCT02788006)
- 2024-02-07Also stopped (terminated): Dana-Farber Cancer Institute, Topical Tazarotene (NCT04071756)
- 2024-02-06Results posted on the registry: Jiangsu HengRui Medicine Co., Ltd., SHR-1210 + Apatinib (NCT03764293)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision