Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 15:55 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Studying An Investigational Drug Crizotinib (PF-02341066) In Non Non-Small Cell Lung Cancer Tumors That Are Positive For Anaplastic Lymphoma Kinase (ALK)
NCT01121588 · Pfizer · PHASE1 · terminated · last registry update 2025-01-23 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Termination of further treatment on the study due to the availability of commercial supply or a rollover study (NCT05160922) that will allow active subjects to continue receiving treatment.” | – | Registry record, Pfizer |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against MET within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-01-13Results posted on the registry: Exelixis, XL184 + erlotinib (NCT00596648)
- 2026-01-08Results posted on the registry: Exelixis, cabozantinib + abiraterone (NCT01995058)
- 2026-01-08Also stopped (terminated): Exelixis, cabozantinib + abiraterone (NCT01995058)
- 2025-12-24Results posted on the registry: Bristol-Myers Squibb, Nivolumab + Sorafenib (NCT01658878)
- 2025-12-18Results posted on the registry: Exelixis, Cabozantinib + Atezolizumab (NCT04446117)
- 2025-12-12Results posted on the registry: National Cancer Institute (NCI), Cabozantinib S-malate + Ipilimumab (NCT04079712)
- 2025-12-11Phase 3 first posted: Janssen Research & Development, LLC, Amivantamab + Pembrolizumab (NCT07276399)
- 2025-12-11Results posted on the registry: Exelixis, Cabozantinib + Cabozantinib (NCT03755791)
- 2025-11-19Results posted on the registry: Joseph Kim, Cabozantinib + Pembrolizumab (NCT05052723)
- 2025-11-12Phase 3 first posted: Merck Sharp & Dohme LLC, Belzutifan + Zanzalintinib (NCT07227402)
- 2025-10-31Results posted on the registry: National Cancer Institute (NCI), Cabozantinib S-malate + Ipilimumab (NCT03914300)
- 2025-10-30Results posted on the registry: Royal Marsden NHS Foundation Trust, Crizotinib Oral Capsule [Xalkori] + Fulvestrant 50 MG/ML Prefilled Syringe [Faslodex or generic] (NCT03620643)
- 2025-10-24Results posted on the registry: AbbVie, Telisotuzumab Vedotin (NCT05513703)
- 2025-10-24Also stopped (terminated): AbbVie, Telisotuzumab Vedotin (NCT05513703)
- 2025-10-20Results posted on the registry: Janssen Research & Development, LLC, Dexamethasone + Montelukast (NCT05663866)
- 2025-10-16Also stopped (terminated): Novartis Pharmaceuticals, capmatinib (NCT04926831)
- 2025-09-10Results posted on the registry: Exelixis, Cabozantinib + Nivolumab (NCT03937219)
- 2025-09-02Results posted on the registry: Exelixis, Cabozantinib (XL184) 140 mg + Cabozantinib (XL184) 60 mg (NCT01896479)
- 2025-08-24Results posted on the registry: John Rieth, Cabozantinib + Pembrolizumab (NCT03957551)
- 2025-08-11Results posted on the registry: University of California, Irvine, Cabozantinib + Pembrolizumab (NCT04164979)
- 2025-07-31Results posted on the registry: M.D. Anderson Cancer Center, Cabozantinib S-malate (NCT02302833)
- 2025-07-17Results posted on the registry: University of Washington, Cabozantinib S-malate (NCT04220229)
- 2025-07-17Also stopped (terminated): University of Washington, Cabozantinib S-malate (NCT04220229)
- 2025-07-16Also stopped (terminated): National Cheng-Kung University Hospital, Crizotinib 250 MG (NCT04030429)
- 2025-06-19Results posted on the registry: Grupo Espanol de Tumores Neuroendocrinos, Cabozantinib 40 mg (NCT04400474)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision