Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 23:06 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Pasireotide (SOM230) With or Without Everolimus in Treating Patients With Hormone Resistant, Chemotherapy Naive Prostate Cancer
NCT01313559 · Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University · PHASE2 · terminated · last registry update 2025-04-30 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Slow accrual” | – | Registry record, Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against SSTR5 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-04-28Results posted on the registry: Grupo Espanol de Tumores Neuroendocrinos, Axitinib + Sandostatin LAR (NCT01744249)
- 2026-04-06Results posted on the registry: ITM Solucin GmbH, 177Lu-edotreotide PRRT + Everolimus (NCT03049189)
- 2026-04-03Also stopped (suspended): Mayo Clinic, Somatostatin analog (NCT04329039)
- 2026-03-18Phase 3 first posted: Shanghai Zhongshan Hospital, Octreotide Microspheres + Placebo (NCT07479784)
- 2026-02-05Also stopped (terminated): Ariceum Therapeutics GmbH, 225Ac-SSO110 + SoC + Atezolizumab (NCT06939036)
- 2026-01-21Results posted on the registry: National Cancer Institute (NCI), Sacituzumab Govitecan + Loperamide (NCT06865677)
- 2026-01-21Also stopped (terminated): National Cancer Institute (NCI), Sacituzumab Govitecan + Loperamide (NCT06865677)
- 2026-01-14Also stopped (terminated): Imperial College London, Lutathera (NCT05987176)
- 2026-01-13Results posted on the registry: Crinetics Pharmaceuticals Inc., Paltusotine + Placebo (NCT04837040)
- 2025-11-20Results posted on the registry: Medical University of South Carolina, Octreotide (NCT03624517)
- 2025-11-20Also stopped (terminated): Medical University of South Carolina, Octreotide (NCT03624517)
- 2025-11-17Also stopped (terminated): Debiopharm International SA, Debio 4126 + Sandostatin LAR (NCT05364944)
- 2025-11-03Results posted on the registry: National Cancer Institute (NCI), Lutetium Lu 177 Dotatate + Triapine (NCT04234568)
- 2025-10-31Results posted on the registry: Crinetics Pharmaceuticals Inc., Randomized: 40 mg Paltusotine + Randomized: 80 mg Paltusotine (NCT05361668)
- 2025-09-10Phase 3 first posted: CSPC ZhongQi Pharmaceutical Technology Co., Ltd., Sirolimus for injection (albumin bound) + Octreotide long-acting injection (NCT07165886)
- 2025-07-25Phase 3 first posted: Crinetics Pharmaceuticals Inc., Paltusotine + Placebo (NCT07087054)
- 2025-07-24Results posted on the registry: Grupo Espanol de Tumores Neuroendocrinos, Lenvatinib (NCT02678780)
- 2025-07-10Phase 3 first posted: HTA Co., Ltd., 177Lu-DOTATATE injection + Octreotide LAR (Long-acting release) (NCT07057622)
- 2025-06-10Also stopped (terminated): Orano Med LLC, AlphaMedix (NCT03466216)
- 2025-06-10Also stopped (terminated): Erasmus Medical Center, Capecitabine (Xeloda) + 177Lu-DOTATATE (NCT07012330)
- 2025-05-09Results posted on the registry: Memorial Sloan Kettering Cancer Center, Octreotide + LAR Lanreotide (NCT03289741)
- 2025-04-16Phase 3 first posted: Debiopharm International SA, Debio 4126 + Placebo (NCT06930625)
- 2025-03-17Phase 3 first posted: Grupo Espanol de Tumores Neuroendocrinos, 177Lu-Dotatate (7.4 Gigabecquerel/cycle) during 30 min intravenous infusion every 16 weeks (q8w) x 4 cycles; 2) and 3) as in the experimental arm. + 177Lu-Dotatate (7.4 Gigabecquerel/cycle) during 30 min intravenous infusion every 8 weeks (q8w) x 4 cycles; 2) and 3) as in the experimental arm. (NCT06878664)
- 2025-03-17Results posted on the registry: Crinetics Pharmaceuticals Inc., Paltusotine + Placebo (NCT03792555)
- 2025-03-03Phase 3 first posted: The Netherlands Cancer Institute, Somatostatin analog (NCT06855095)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision