Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 00:42 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Doxycycline, Temozolomide and Ipilimumab in Melanoma
NCT01590082 · M.D. Anderson Cancer Center · PHASE1/PHASE2 · terminated · last registry update 2020-09-02 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Accrual slow due to alternate trials and treatment options.” | – | Registry record, M.D. Anderson Cancer Center |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against MMP7 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2021-08-02Also stopped (terminated): Cadrock Pty. Ltd., Doxycycline Capsule + Azithromycin Capsule (NCT03618108)
- 2021-06-30Results posted on the registry: Emergent BioSolutions, Ciprofloxacin 500Mg Tablet + Doxycycline 100Mg Tablet (NCT04067011)
- 2021-06-23Results posted on the registry: Radboud University Medical Center, Doxycycline + Placebo (NCT01318356)
- 2021-04-27Also stopped (terminated): Rochester General Hospital, Doxycycline monohydrate (NCT02341209)
- 2021-04-19Also stopped (withdrawn): Temple University, Doxycycline + Placebo (NCT04433078)
- 2021-04-13Results posted on the registry: State University of New York - Upstate Medical University, Chloroquine + Atovaquone and Proguanil (NCT02564471)
- 2021-04-09Phase 3 first posted: Assistance Publique - Hôpitaux de Paris, BPG + Doxycycline (NCT04838717)
- 2021-04-08Also stopped (terminated): Weill Medical College of Cornell University, Antimicrobial therapy: Co-trimoxazole or Doxycycline (NCT02759120)
- 2021-04-06Also stopped (terminated): Julio Ramirez, oral antibiotics (NCT02099240)
- 2021-03-25Results posted on the registry: PATH, iOWH032 + Placebo (NCT04150250)
- 2021-03-03Results posted on the registry: Weill Medical College of Cornell University, Antimicrobial therapy: Co-trimoxazole or Doxycycline (NCT02759120)
- 2021-01-26Phase 3 first posted: Rothman Institute Orthopaedics, Bactrim + Cefadroxil (NCT04723940)
- 2021-01-26Results posted on the registry: Petra M. Casey, Doxycycline + Placebo (NCT01658995)
- 2021-01-07Results posted on the registry: National Institute of Allergy and Infectious Diseases (NIAID), Azithromycin + Doxycycline (NCT03608774)
- 2020-12-17Results posted on the registry: University of Hawaii, Doxycycline (NCT01469585)
- 2020-12-04Results posted on the registry: Brigham and Women's Hospital, Tauroursodeoxycholic Acid and Doxycycline (NCT01855360)
- 2020-12-02Phase 3 first posted: K.R. van Straalen, Metformin (NCT04649502)
- 2020-11-19Phase 3 first posted: Rothman Institute Orthopaedics, Doxycycline 100 MG Oral Tablet (NCT04636125)
- 2020-10-22Phase 3 first posted: ANRS, Emerging Infectious Diseases, Experimental: doxycycline + Bexsero® vaccine (NCT04597424)
- 2020-10-14Phase 3 first posted: Hedi Gharsallah, Doxycyclin (NCT04584567)
- 2020-10-09Results posted on the registry: Dhaka Medical College, Ivermectin and Doxycycline + Standard of care (NCT04523831)
- 2020-08-27Also stopped (withdrawn): Abderrahmane Mami Hospital, HCQ + Azithromycin (NCT04528927)
- 2020-08-27Phase 3 first posted: Abderrahmane Mami Hospital, HCQ + Azithromycin (NCT04528927)
- 2020-08-24Phase 3 first posted: Dhaka Medical College, Ivermectin and Doxycycline + Standard of care (NCT04523831)
- 2020-06-02Phase 3 first posted: PolyPid Ltd., D-PLEX (NCT04411199)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision