Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 04:07 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Safety, Tolerability, and Efficacy of IA Verapamil in the Treatment of Joint Pain in Subjects With Osteoarthritis of the Knee
NCT01645709 · Calosyn Pharma, Inc. · PHASE1/PHASE2 · terminated · last registry update 2014-09-05 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Sponsor decision to terminate study” | – | Registry record, Calosyn Pharma, Inc. |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against CACNA1C within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2015-06-10Also stopped (terminated): The University of Western Australia, Verapamil + Kenalog 10 (NCT01720056)
- 2015-05-21Results posted on the registry: Food and Drug Administration (FDA), Ranolazine + Dofetilide (NCT01873950)
- 2015-04-07Results posted on the registry: Brigham and Women's Hospital, Diltiazem + Placebo (NCT00319982)
- 2015-02-27Results posted on the registry: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Lisinopril + Telmisartan (NCT00283686)
- 2015-01-26Results posted on the registry: Daiichi Sankyo Co., Ltd., DU-176b 15mg + DU-176b 30mg (NCT01857622)
- 2015-01-09Also stopped (withdrawn): Ottawa Hospital Research Institute, Amlodipine + Diltiazem (NCT01549496)
- 2015-01-08Also stopped (withdrawn): University of Michigan, Esmolol (NCT01232400)
- 2014-12-11Results posted on the registry: The Cleveland Clinic, nicardipine intravenous + Labetalol (NCT00765648)
- 2014-09-15Results posted on the registry: National Heart, Lung, and Blood Institute (NHLBI), Anti-hyperglycemic Agents + Anti-hypertensive Agents (NCT00000620)
- 2014-08-29Results posted on the registry: University of Florida, Nicardipine hydrochloride + Preservative-free normal saline (NCT01810302)
- 2014-08-29Also stopped (terminated): University of Florida, Nicardipine hydrochloride + Preservative-free normal saline (NCT01810302)
- 2014-08-29Results posted on the registry: Northwestern University, Nicardipine + Esmolol (NCT01951950)
- 2014-08-19Results posted on the registry: The Medicines Company, Clevidipine + Standard of Care IV antihypertensive (NCT00803634)
- 2014-08-06Also stopped (terminated): Sanofi, Dronedarone + Placebo (for dronedarone) (NCT01026090)
- 2014-08-01Also stopped (terminated): Duke University, Nicardipine + 0.9% saline (NCT00508118)
- 2014-07-01Results posted on the registry: S.L.A. Pharma AG, Diltiazem hydrochloride 4% cream + Diltiazem hydrochloride 2% cream (NCT01217515)
- 2014-06-17Results posted on the registry: Boehringer Ingelheim, Verapamil + BI 10773 (NCT01276301)
- 2014-06-02Results posted on the registry: State Health Center, Hungary, Verapamil + Placebo (NCT01402427)
- 2014-04-14Results posted on the registry: Ventrus Biosciences, Inc, Clarithromycin XL + 2% Diltiazem (NCT02080780)
- 2013-12-20Phase 3 first posted: Prof Brian Lawlor, Nilvadipine + Placebo (NCT02017340)
- 2013-12-16Results posted on the registry: Antonios Likourezos, Metoprolol + Diltiazem (NCT01914926)
- 2013-11-14Phase 3 first posted: Chong Kun Dang Pharmaceutical, TELMINUVO Tab. (80/2.5mg) + TELMINUVO Tab. (80/5mg) (NCT01983735)
- 2013-10-28Results posted on the registry: The George Institute, a drug against CACNA1C (NCT00716079)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision