Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 01:14 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Adjunctive Isradipine for the Treatment of Bipolar Depression
NCT01784666 · Massachusetts General Hospital · PHASE2 · terminated · last registry update 2017-04-20 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Lack of Enrollment” | – | Registry record, Massachusetts General Hospital |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against CACNA1C within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2018-04-11Also stopped (terminated): Center Laboratories, Inc., R-verapamil 75 mg tablet + Placebo (NCT02209155)
- 2018-02-23Results posted on the registry: AstraZeneca, AZD7986 + Verapamil (NCT02653872)
- 2017-11-14Phase 3 first posted: Keimyung University Dongsan Medical Center, Phloroglucin(Flospan®) + Normal saline (NCT03342118)
- 2017-05-16Results posted on the registry: Yale University, Ranolazine + Placebo (NCT02052011)
- 2017-04-25Results posted on the registry: University of Minnesota, Intravenous nicardipine hydrochloride (NCT01176565)
- 2017-04-25Also stopped (terminated): University of Minnesota, Intravenous nicardipine hydrochloride (NCT01176565)
- 2017-04-13Results posted on the registry: University of Utah, Hydroxyurea + Verapamil (NCT00706810)
- 2017-01-06Results posted on the registry: Corewell Health East, Ranolazine + Placebo (NCT01352416)
- 2017-01-06Also stopped (terminated): Corewell Health East, Ranolazine + Placebo (NCT01352416)
- 2016-12-28Results posted on the registry: Benjamin Bleier, Verapamil HCl (NCT02454608)
- 2016-09-23Also stopped (withdrawn): Justin Fraser, Verapamil and Citicoline (NCT02823106)
- 2016-09-16Results posted on the registry: Pfizer, itraconazole + diltiazem (NCT02319148)
- 2016-06-08Results posted on the registry: Food and Drug Administration (FDA), Dofetilide + Mexiletine (NCT02308748)
- 2016-05-13Phase 3 first posted: Meshalkin Research Institute of Pathology of Circulation, Metoprolol + Verapamil (NCT02772354)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision