Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 23:03 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Amlexanox for Type 2 Diabetes and Obesity
NCT01842282 · University of Michigan · PHASE2 · terminated · last registry update 2024-05-07 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Due to limited funding, trial was suspended, intending to restart with additional funds; then preliminary results were obtained, and research moved on to placebo controlled trial. Results for both have been published.” | – | Registry record, University of Michigan |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against PDE4A within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-04-18Results posted on the registry: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA, Ensifentrine 3 mg twice daily (NCT06460493)
- 2025-04-13Results posted on the registry: Bristol-Myers Squibb, Deucravacitinib + Apremilast (NCT04908189)
- 2025-04-09Results posted on the registry: Amgen, Apremilast + Placebo (NCT05174065)
- 2025-03-13Also stopped (withdrawn): University of Nebraska, CYR-064 (NCT06498687)
- 2025-03-07Phase 3 first posted: SFA Therapeutics, SFA002 + Otezla (NCT06863493)
- 2025-02-21Results posted on the registry: Rutgers, The State University of New Jersey, Dipyridamole ER 200mg/ Aspirin 25mg orally/enterally AND Standard of care (NCT04410328)
- 2024-11-27Results posted on the registry: University of California, Los Angeles, Ibudilast + Placebo oral capsule (NCT03594435)
- 2024-10-30Results posted on the registry: MediciNova, Ibudilast + Placebo (NCT04429555)
- 2024-10-29Results posted on the registry: University of Miami, Theophylline ER + Placebo oral tablet (NCT03984188)
- 2024-10-15Results posted on the registry: University of Missouri-Columbia, Pentoxifylline + Placebo (NCT02592863)
- 2024-10-15Also stopped (terminated): University of Missouri-Columbia, Pentoxifylline + Placebo (NCT02592863)
- 2024-10-01Results posted on the registry: Philips Clinical & Medical Affairs Global, a drug against PDE4A (NCT04696354)
- 2024-09-25Also stopped (terminated): Iain Bressendorff, ACEi / ARB, SGLT2i, finerenone, semaglutide, pentoxifylline, hydrochlorthiazide, baricitinib (NCT05897372)
- 2024-09-24Results posted on the registry: MediciNova, ibudilast + Ibudilast (NCT02714036)
- 2024-09-19Phase 3 first posted: Alumis Inc, Envudeucitinib + Placebo (NCT06588738)
- 2024-09-19Phase 3 first posted: Alumis Inc, Envudeucitinib + Apremilast (NCT06586112)
- 2024-06-14Phase 3 first posted: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA, Ensifentrine 3 mg twice daily (NCT06460493)
- 2024-05-20Phase 3 first posted: Ain Shams University, Dapagliflozin 10mg Tab + Pentoxifylline 400 MG (NCT06421870)
- 2024-05-20Phase 3 first posted: Tanta University, Pentoxifylline + Probiotic Formula (NCT06422000)
- 2024-04-30Results posted on the registry: AbbVie, Risankizumab + Apremilast (NCT04908475)
- 2024-04-19Results posted on the registry: Tufts Medical Center, Apremilast (NCT04306965)
- 2024-04-16Results posted on the registry: Psoriasis Treatment Center of Central New Jersey, Otezla (NCT03587194)
- 2024-01-11Also stopped (terminated): Baylor College of Medicine, Pentoxifylline (NCT01774487)
- 2024-01-09Phase 3 first posted: Mahidol University, Aminophylline (NCT06196853)
- 2024-01-09Results posted on the registry: Massachusetts General Hospital, Theophylline (NCT02479451)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision