Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 15:44 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
A Pilot Treatment Study of Insulin-Like Growth Factor-1 (IGF-1) in Autism Spectrum Disorder
NCT01970345 · Icahn School of Medicine at Mount Sinai · PHASE2 · terminated · last registry update 2024-02-08 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Decision made to terminate due to difficulty in procurement of adequate supply of treatment drug. Decision made on April 2023 to terminate study.” | – | Registry record, Icahn School of Medicine at Mount Sinai |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against IGF1R within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2024-11-20Also stopped (terminated): Astellas Pharma Inc, OSI-906 + Placebo (NCT01101906)
- 2024-11-08Results posted on the registry: NantBioScience, Inc., Gemcitabine + AMG 479 (NCT01318642)
- 2024-11-08Also stopped (terminated): NantBioScience, Inc., Gemcitabine + AMG 479 (NCT01318642)
- 2024-10-17Results posted on the registry: NantCell, Inc., AMG 479 + AMG 655 (NCT00630552)
- 2024-09-25Results posted on the registry: NantCell, Inc., AMG 479 + AMG 479 (NCT00807612)
- 2024-09-25Also stopped (terminated): NantCell, Inc., AMG 479 + AMG 479 (NCT00807612)
- 2024-09-19Results posted on the registry: NantCell, Inc., AMG 479 + Placebo (NCT00626106)
- 2024-08-23Results posted on the registry: NantCell, Inc., AMG 479 + Etoposide (NCT00791154)
- 2024-08-23Also stopped (terminated): NantCell, Inc., AMG 479 + Etoposide (NCT00791154)
- 2024-08-20Results posted on the registry: NantCell, Inc., AMG 479 + AMG 655 (NCT00819169)
- 2024-08-20Also stopped (terminated): NantCell, Inc., AMG 479 + AMG 655 (NCT00819169)
- 2024-08-01Also stopped (terminated): Dana-Farber Cancer Institute, Palbociclib + Ganitumab (NCT04129151)
- 2024-07-17Results posted on the registry: Dana-Farber Cancer Institute, Palbociclib + Ganitumab (NCT04129151)
- 2024-07-16Results posted on the registry: NantCell, Inc., AMG 479 + Placebo (NCT01231347)
- 2024-06-28Also stopped (terminated): Amgen, TEPEZZA (NCT04478994)
- 2024-04-26Results posted on the registry: Amgen, TEPEZZA + Placebo (NCT04583735)
- 2024-04-25Phase 3 first posted: Viridian Therapeutics, Inc., Veligrotug (NCT06384547)
- 2024-04-19Results posted on the registry: Amgen, TEPEZZA (NCT04478994)
- 2024-02-28Results posted on the registry: Children's Hospital Medical Center, Cincinnati, Increlex (NCT02636270)
- 2024-02-08Phase 3 first posted: Amgen, Teprotumumab (NCT06248619)
- 2023-12-22Phase 3 first posted: Viridian Therapeutics, Inc., Veligrotug (NCT06179875)
- 2023-11-01Phase 3 first posted: Sling Therapeutics, Inc., linsitinib (NCT06112340)
- 2023-09-01Phase 3 first posted: Viridian Therapeutics, Inc., Veligrotug + Placebo (NCT06021054)
- 2023-07-06Results posted on the registry: Ipsen, mecasermin (NCT00571727)
- 2023-05-22Results posted on the registry: Rush University Medical Center, AXL1717 (NCT01721577)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision