Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 06:04 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
A Study Conducted in Subjects With Relapsed/Refractory Multiple Myeloma (MM); to Determine Dose of Afuresertib in Combination With Carfilzomib (Part 1) and to Investigate the Safety, Pharmacokinetic and Clinical Activity of the Combination Compared With Carfilzomib Alone (Part 2)
NCT02235740 · Novartis · PHASE1 · terminated · last registry update 2016-05-04 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
No reason was published
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | The registry record gives no reason | – | Registry record, Novartis |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against AKT2 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2017-04-07Results posted on the registry: National Cancer Institute (NCI), Akt Inhibitor MK2206 (NCT01481129)
- 2017-03-07Phase 3 first posted: Hoffmann-La Roche, Ipatasertib + Abiraterone (NCT03072238)
- 2016-10-17Results posted on the registry: National Cancer Institute (NCI), Akt Inhibitor MK2206 + Erlotinib Hydrochloride (NCT01294306)
- 2016-10-06Also stopped (withdrawn): GlaxoSmithKline, Afuresertib + Enzalutamide (NCT02380313)
- 2016-06-28Results posted on the registry: National Cancer Institute (NCI), Akt Inhibitor MK2206 + Bendamustine Hydrochloride (NCT01369849)
- 2016-06-24Results posted on the registry: National Cancer Institute (NCI), Akt Inhibitor MK2206 (NCT01283035)
- 2016-05-25Results posted on the registry: AstraZeneca, AZD5363 + AZD5363 (NCT01895946)
- 2016-04-15Results posted on the registry: National Cancer Institute (NCI), Akt Inhibitor MK2206 (NCT01425879)
- 2016-03-28Results posted on the registry: Genentech, Inc., Ipatasertib + Cobimetinib (NCT01562275)
- 2016-03-10Also stopped (withdrawn): Dana-Farber Cancer Institute, MK-2206 (NCT01249105)
- 2016-03-09Results posted on the registry: National Cancer Institute (NCI), Akt Inhibitor MK2206 + Fluorouracil (NCT01658943)
- 2016-02-18Results posted on the registry: Memorial Sloan Kettering Cancer Center, MK-2206 (NCT01169649)
- 2016-02-12Results posted on the registry: National Cancer Institute (NCI), Akt Inhibitor MK2206 (NCT01277757)
- 2015-11-18Also stopped (terminated): Memorial Sloan Kettering Cancer Center, MK-2206 (NCT01186705)
- 2015-11-10Results posted on the registry: National Cancer Institute (NCI), Akt inhibitor MK2206 (NCT01258998)
- 2015-10-05Results posted on the registry: National Cancer Institute (NCI), Akt Inhibitor MK2206 (NCT01239355)
- 2015-10-05Also stopped (terminated): National Cancer Institute (NCI), Akt Inhibitor MK2206 (NCT01239355)
- 2015-08-27Also stopped (terminated): National Cancer Institute (NCI), Akt Inhibitor MK2206 + Lapatinib Ditosylate (NCT01281163)
- 2015-06-26Results posted on the registry: National Cancer Institute (NCI), Akt Inhibitor MK2206 (NCT01604772)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision