Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 15:53 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
OLAParib COmbinations
NCT02576444 · Joseph Paul Eder · PHASE2 · terminated · last registry update 2022-12-28 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “The study was paused during COVID and without the ability to initiate the 4th arm in the study, the decision was to terminate the study in 2022.” | – | Registry record, Joseph Paul Eder |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against PARP1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2023-11-18Phase 3 first posted: Tokyo Medical and Dental University, Systemic therapy for 12 weeks after primary registration + Same systemic therapy after secondary registration (NCT06135714)
- 2023-11-18Results posted on the registry: Janssen Research & Development, LLC, Niraparib 200 mg + Cetrelimab 240 mg (NCT03431350)
- 2023-11-01Phase 3 first posted: AstraZeneca, Dato-DXd + Durvalumab (NCT06112379)
- 2023-10-13Results posted on the registry: National Cancer Institute (NCI), Olaparib + Tremelimumab (NCT04034927)
- 2023-10-13Results posted on the registry: AstraZeneca, Olaparib + MEDI4736 (NCT02734004)
- 2023-10-04Results posted on the registry: Janssen Research & Development, LLC, Niraparib + Abiraterone Acetate (NCT03748641)
- 2023-09-21Results posted on the registry: National Cancer Institute (NCI), Olaparib + Temozolomide (NCT03880019)
- 2023-07-19Results posted on the registry: National Cancer Institute (NCI), Topotecan Hydrochloride + Veliparib (NCT01012817)
- 2023-07-03Results posted on the registry: University of Pennsylvania, Niraparib + Nivolumab + Niraparib + Ipilimumab (NCT03404960)
- 2023-07-03Results posted on the registry: Massachusetts General Hospital, Niraparib + Dostarlimab (NCT04409002)
- 2023-06-15Results posted on the registry: AstraZeneca, olaparib + abiraterone acetate (NCT03732820)
- 2023-06-09Results posted on the registry: National Cancer Institute (NCI), Capecitabine + Fluorouracil (NCT02921256)
- 2023-04-04Results posted on the registry: National Cancer Institute (NCI), Temozolomide + Veliparib (NCT02152982)
- 2023-03-28Results posted on the registry: National Cancer Institute (NCI), Cediranib Maleate + Olaparib (NCT02345265)
- 2022-12-21Phase 3 first posted: GOG Foundation, Cisplatin (NCT05659381)
- 2022-12-12Results posted on the registry: AstraZeneca, Durvalumab + Placebo for Olaparib (NCT03775486)
- 2022-11-14Phase 3 first posted: UNICANCER, Futibatinib + Ivosidenib (NCT05615818)
- 2022-10-26Results posted on the registry: AstraZeneca, Durvalumab + Olaparib (NCT03459846)
- 2022-06-27Phase 3 first posted: National Cancer Institute (NCI), Olaparib + Pazopanib (NCT05432791)
- 2022-05-18Results posted on the registry: University of Washington, Olaparib + Testosterone Enanthate (NCT03516812)
- 2022-04-28Results posted on the registry: Incyte Corporation, INCB057643 + Gemcitabine (NCT02711137)
- 2022-03-22Results posted on the registry: AstraZeneca, Olaparib Continuous (28-Day cycle) 300 mg BD. + Ceralasertib 160 mg OD + olaparib continuous 300 mg BD (28-day cycle). (NCT03330847)
- 2022-03-08Results posted on the registry: Janssen Research & Development, LLC, Niraparib (NCT02854436)
- 2022-02-09Results posted on the registry: Bristol-Myers Squibb, nivolumab + docetaxel (NCT03338790)
- 2021-12-29Phase 3 first posted: AstraZeneca, olaparib + abiraterone acetate (NCT05171816)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision