Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 06:02 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Dextromethorphan Pediatric Acute Cough Study
NCT02651116 · Pfizer · PHASE4 · terminated · last registry update 2021-04-28 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “The study was prematurely discontinued due to slow enrollment during the 2019/2020 cold season. No safety or efficacy concerns led to the decision to terminate” | – | Registry record, Pfizer |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against SIGMAR1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2022-03-02Also stopped (terminated): Genprex, Inc., DOTAP:Chol-TUSC2 + Erlotinib (NCT01455389)
- 2021-11-26Results posted on the registry: Avanir Pharmaceuticals, AVP-923-20 + Placebo (NCT01584440)
- 2021-11-22Results posted on the registry: Avanir Pharmaceuticals, AVP-923-45 + AVP-923-30 (NCT01324232)
- 2021-09-24Results posted on the registry: Axsome Therapeutics, Inc., AXS-05 + Bupropion (NCT03595579)
- 2021-09-16Results posted on the registry: University of Colorado, Denver, metoprolol succinate + Genotyping (NCT02293096)
- 2021-09-16Also stopped (terminated): University of Colorado, Denver, metoprolol succinate + Genotyping (NCT02293096)
- 2021-07-01Phase 3 first posted: Axsome Therapeutics, Inc., AXS-05 (dextromethorphan-bupropion) + Placebo (NCT04947553)
- 2021-05-24Also stopped (terminated): Emalex Biosciences Inc., ecopipam HCl ~2mg/kg/day + Cohort 1 Probe Cocktail (NCT04764851)
- 2021-03-15Phase 3 first posted: Axsome Therapeutics, Inc., AXS-05 + Placebo (NCT04797715)
- 2021-02-05Results posted on the registry: Arlyne Thung, Dextromethorphan + Acetaminophen (NCT03714919)
- 2020-12-29Phase 3 first posted: National Cheng-Kung University Hospital, Dextromethorphan + Memantine (NCT04687566)
- 2020-10-27Also stopped (withdrawn): Takeda, Caffeine + Losartan (NCT02760615)
- 2020-10-26Results posted on the registry: Otsuka Pharmaceutical Development & Commercialization, Inc., AVP-786 + Placebo (NCT02534038)
- 2020-09-16Results posted on the registry: Otsuka Pharmaceutical Development & Commercialization, Inc., AVP-786 + Placebo (NCT02477670)
- 2020-08-06Results posted on the registry: Study Investigator-Sponsor, Dextromethorphan Hydrobromide + Avicel PH101 (Microcrystalline Cellulose NF) for Compounding (NCT03480009)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision