Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 15:53 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
BAY 1000394 for MCL-1-, MYC-, and CCNE1-Amplified Tumors
NCT02656849 · Dana-Farber Cancer Institute · PHASE2 · withdrawn · last registry update 2016-07-01 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Development of BAY1000394 has been terminated by Bayer.” | – | Registry record, Dana-Farber Cancer Institute |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against CDK1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2017-06-06Results posted on the registry: National Cancer Institute (NCI), alvocidib + daunorubicin hydrochloride (NCT01349972)
- 2017-06-02Results posted on the registry: National Cancer Institute (NCI), alvocidib (NCT00058240)
- 2017-04-04Also stopped (terminated): National Cancer Institute (NCI), dinaciclib (NCT01026324)
- 2017-03-10Results posted on the registry: National Cancer Institute (NCI), Alvocidib Hydrochloride + Fluorouracil (NCT00957905)
- 2016-10-24Results posted on the registry: National Cancer Institute (NCI), alvocidib (NCT00098371)
- 2016-10-24Also stopped (terminated): National Cancer Institute (NCI), alvocidib (NCT00098371)
- 2016-08-10Also stopped (withdrawn): Yonsei University, BAY 1000394 (Roniciclib) in combination with docetaxel (NCT02522910)
- 2016-08-08Results posted on the registry: National Cancer Institute (NCI), alvocidib (NCT00112723)
- 2016-08-08Also stopped (terminated): National Cancer Institute (NCI), alvocidib (NCT00112723)
- 2016-08-03Results posted on the registry: National Cancer Institute (NCI), dinaciclib (NCT01026324)
- 2016-07-22Results posted on the registry: National Cancer Institute (NCI), Dinaciclib (NCT00937937)
- 2015-11-11Also stopped (terminated): National Cancer Institute (NCI), Alvocidib Hydrochloride + Cyclophosphamide (NCT01076556)
- 2015-08-07Also stopped (terminated): Merck Sharp & Dohme LLC, SCH 727965 + Bortezomib (NCT00871546)
- 2015-07-07Results posted on the registry: National Cancer Institute (NCI), alvocidib + mitoxantrone hydrochloride (NCT00634244)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision