Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 00:49 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Influence of Carboxypeptidase D (CPD) Gene on Body Weight and Fat Mass Reduction by Perindopril in Obese Subjects
NCT02777489 · Gene PreDiT · PHASE2 · terminated · last registry update 2017-08-03 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Unproven hypothesis” | – | Registry record, Gene PreDiT |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against ACE within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2018-01-11Also stopped (withdrawn): Vanderbilt University Medical Center, Valsartan 80 mg bid + Enalapril 10 mg bid (NCT03005184)
- 2017-12-11Results posted on the registry: University of Nebraska, ACEI continuation + ACEI omission (NCT01669434)
- 2017-09-28Results posted on the registry: Duke University, ACE-I Cessation group + ACE-I Continuation group (NCT01867047)
- 2017-09-28Also stopped (terminated): Duke University, ACE-I Cessation group + ACE-I Continuation group (NCT01867047)
- 2017-08-29Phase 3 first posted: South Tees Hospitals NHS Foundation Trust, Enalapril (NCT03265574)
- 2017-08-15Phase 3 first posted: Ospedale San Raffaele, Peri + HCTZ (NCT03249285)
- 2017-08-11Phase 3 first posted: Boryung Pharmaceutical Co., Ltd, Fimasartan or Fimasartan/Hydrochlorothiazide + Perindopril or Perindopril/Indapamide (NCT03246555)
- 2017-05-11Also stopped (terminated): KU Leuven, Active treatment with nitrendipine (10-40 mg/day). (NCT02088450)
- 2017-03-08Phase 3 first posted: University Medical Center Groningen, Fosinopril + Pravastatin (NCT03073018)
- 2017-02-28Phase 3 first posted: Novartis Pharmaceuticals, sacubitril/valsartan + Enalapril (NCT03066804)
- 2017-02-24Also stopped (terminated): Haukeland University Hospital, Bevacizumab + Propranolol (NCT01705392)
- 2016-11-25Results posted on the registry: Novartis Pharmaceuticals, Enalapril + Aliskiren (NCT00853658)
- 2016-09-14Phase 3 first posted: Novartis Pharmaceuticals, LCZ696 (Sacubitril/Valsartan) + Placebo of LCZ696 (Sacubitril/Valsartan) (NCT02900378)
- 2016-08-15Also stopped (terminated): Novartis Pharmaceuticals, LCZ696 200 mg BID + Enalapril 10 mg BID (NCT01035255)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision