Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 07:34 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Treatment of Macrophage Activation Syndrome (MAS) With Anakinra
NCT02780583 · University of Alabama at Birmingham · PHASE1 · terminated · last registry update 2024-08-01 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “no further funding to continue, investigator relocated, no replacement found to continue” | – | Registry record, University of Alabama at Birmingham |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against IL1R1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-06-06Results posted on the registry: Assistance Publique - Hôpitaux de Paris, Anakinra (NCT04341584)
- 2025-05-20Results posted on the registry: Herlev and Gentofte Hospital, Anakinra + Sodium Chloride 9mg/ml Injection (NCT05498467)
- 2025-05-04Results posted on the registry: Marcela V. Maus, M.D.,Ph.D., Anakinra + Axicabtagene Ciloleucel (NCT04150913)
- 2025-01-29Also stopped (terminated): University Hospital, Basel, Switzerland, Anakinra Prefilled Syringe (NCT04227769)
- 2025-01-28Results posted on the registry: M.D. Anderson Cancer Center, Anakinra + Axicabtagene Ciloleucel (NCT04432506)
- 2024-12-27Results posted on the registry: National Institute of Neurological Disorders and Stroke (NINDS), Anakinra (NCT04025554)
- 2024-05-24Results posted on the registry: Juno Therapeutics, a Subsidiary of Celgene, JCARH125 + JCARH125 + anakinra (NCT03430011)
- 2024-03-29Phase 3 first posted: Assistance Publique - Hôpitaux de Paris, ANAKINRA (NCT06336733)
- 2024-03-04Results posted on the registry: University of California, San Diego, Anakinra (NCT02179853)
- 2023-08-24Results posted on the registry: University of Alabama at Birmingham, Anakinra + Normal saline (NCT04362111)
- 2023-08-21Also stopped (terminated): Tceleron Therapeutics, Inc., CART-PSMA-TGFβRDN + Cyclophosphamide (NCT04227275)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision