Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 16:08 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Evaluating the Effect of Isotretinoin in Regulatory T-cell Function in Adverse Cutaneous Drug Eruptions (ACDEs): A Pilot Study
NCT02795143 · Massachusetts General Hospital · NA · withdrawn · last registry update 2023-06-07 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “PI (Responsible Party) transferred to new institution prior to enrollment and protocol was closed.” | – | Registry record, Massachusetts General Hospital |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against RARG within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2024-05-20Results posted on the registry: Memorial Sloan Kettering Cancer Center, decitabine + tretinoin (NCT00382200)
- 2024-05-17Results posted on the registry: Clementia Pharmaceuticals Inc., Palovarotene dose level 1 + Palovarotene dose level 2 (NCT02279095)
- 2024-05-08Also stopped (terminated): University Hospital Regensburg, low-dose Azacitidine + Pioglitazone (NCT02942758)
- 2024-04-30Results posted on the registry: Icahn School of Medicine at Mount Sinai, 5-Azacitidine + all trans retinoic acid (NCT03572387)
- 2024-04-15Results posted on the registry: Galderma R&D, Adapalene/Benzoyl Peroxide + Adapalene Gel, 0.1% (NCT00422240)
- 2024-03-06Also stopped (withdrawn): University of Oklahoma, Benzoyl peroxide + Adapalene Gel (NCT05536882)
- 2024-03-04Also stopped (terminated): OHSU Knight Cancer Institute, Abemaciclib + Abiraterone (NCT03878524)
- 2024-02-07Also stopped (terminated): Dana-Farber Cancer Institute, Topical Tazarotene (NCT04071756)
- 2024-02-06Results posted on the registry: Beth Israel Deaconess Medical Center, Altreno + Benzoyl peroxide (NCT04548349)
- 2024-02-05Phase 3 first posted: Mostafa Bahaa, ISOtretinoin 20 MG (NCT06242288)
- 2024-01-19Phase 3 first posted: Srinakharinwirot University, 0.025% Tretinoin (NCT06213987)
- 2023-12-28Results posted on the registry: Galderma R&D, Product A + Product B (NCT02755545)
- 2023-12-20Results posted on the registry: Galderma R&D, Trifarotene Cream + Trifarotene Vehicle Cream (NCT05089708)
- 2023-12-15Phase 3 first posted: National Cancer Institute (NCI), Carboplatin + Cisplatin (NCT06172296)
- 2023-11-15Results posted on the registry: Dana-Farber Cancer Institute, Topical Tazarotene (NCT04071756)
- 2023-11-07Results posted on the registry: Masonic Cancer Center, University of Minnesota, Stem Cell Transplant + Preparative Regimen (NCT00167219)
- 2023-10-27Results posted on the registry: Icahn School of Medicine at Mount Sinai, Duobrii® (NCT04720105)
- 2023-08-14Results posted on the registry: Mayne Pharma International Pty Ltd, CD5789 Cream 200 µg/g + CD5789 Cream 100 µg/g (NCT03738800)
- 2023-08-14Also stopped (terminated): Mayne Pharma International Pty Ltd, CD5789 Cream 200 µg/g + CD5789 Cream 100 µg/g (NCT03738800)
- 2023-07-11Results posted on the registry: Imago BioSciences, Inc., a subsidiary of Merck & Co., Inc., (Rahway, New Jersey USA), bomedemstat + tretinoin (NCT02842827)
- 2023-07-11Results posted on the registry: Galderma R&D, Adapalene/Benzoyl Peroxide (NCT00446043)
- 2023-06-12Results posted on the registry: Incyte Corporation, INCB059872 + all-trans retinoic acid (ATRA) (NCT02712905)
- 2023-04-13Also stopped (withdrawn): University of Louisville, Topical Adapalene Gel 0.1% (NCT04823845)
- 2023-04-06Also stopped (withdrawn): Massachusetts General Hospital, a drug against RARG (NCT03707236)
- 2023-03-14Results posted on the registry: National Cancer Institute (NCI), Carboplatin + Cisplatin (NCT03786783)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision