Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 07:05 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
The Effect of Combination Lumacaftor and Ivacaftor on Markers of Hyperglycemia
NCT02858843 · Massachusetts General Hospital · NA · terminated · last registry update 2018-05-21 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “We were unable to enroll eligible subjects for the study.” | – | Registry record, Massachusetts General Hospital |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against CFTR within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2019-01-08Results posted on the registry: Vertex Pharmaceuticals Incorporated, Ivacaftor + Tezacaftor/Ivacaftor (NCT02412111)
- 2018-11-19Results posted on the registry: Vertex Pharmaceuticals Incorporated, ivacaftor + Placebo (NCT02742519)
- 2018-11-19Also stopped (terminated): Vertex Pharmaceuticals Incorporated, ivacaftor + Placebo (NCT02742519)
- 2018-10-30Results posted on the registry: Vertex Pharmaceuticals Incorporated, LUM/IVA (NCT02797132)
- 2018-10-02Phase 3 first posted: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT03691779)
- 2018-10-02Results posted on the registry: Vertex Pharmaceuticals Incorporated, LUM/IVA + Placebo (NCT03061331)
- 2018-09-27Results posted on the registry: Vertex Pharmaceuticals Incorporated, LUM/IVA (NCT02823470)
- 2018-09-27Also stopped (terminated): Vertex Pharmaceuticals Incorporated, LUM/IVA (NCT02823470)
- 2018-08-16Phase 3 first posted: Vertex Pharmaceuticals Incorporated, VX-659/TEZ/IVA + IVA (NCT03633526)
- 2018-08-06Results posted on the registry: Medical University of South Carolina, Ivacaftor (NCT02934698)
- 2018-07-27Results posted on the registry: Vertex Pharmaceuticals Incorporated, Tezacaftor/Ivacaftor + Ivacaftor (NCT02508207)
- 2018-07-26Phase 3 first posted: Vertex Pharmaceuticals Incorporated, LUM + IVA (NCT03601637)
- 2018-06-15Phase 3 first posted: Vertex Pharmaceuticals Incorporated, TEZ/IVA + IVA (NCT03559062)
- 2018-06-12Results posted on the registry: Vertex Pharmaceuticals Incorporated, VX-661 Plus Ivacaftor Combination + Ivacaftor (NCT02347657)
- 2018-06-12Results posted on the registry: Vertex Pharmaceuticals Incorporated, VX-661 plus ivacaftor combination + Ivacaftor (NCT02516410)
- 2018-06-12Results posted on the registry: Vertex Pharmaceuticals Incorporated, VX-661/Ivacaftor + Ivacaftor (NCT02392234)
- 2018-05-25Phase 3 first posted: Vertex Pharmaceuticals Incorporated, TEZ/IVA + IVA (NCT03537651)
- 2018-05-15Phase 3 first posted: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT03525574)
- 2018-05-15Phase 3 first posted: Vertex Pharmaceuticals Incorporated, VX-445/TEZ/IVA + IVA (NCT03525444)
- 2018-05-15Phase 3 first posted: Vertex Pharmaceuticals Incorporated, VX-445/TEZ/IVA + TEZ/IVA (NCT03525548)
- 2018-04-20Results posted on the registry: Richard Barry Moss, Ivacaftor + β-Adrenergic cocktail (NCT02310789)
- 2018-04-13Results posted on the registry: Vertex Pharmaceuticals Incorporated, VX-661 + Ivacaftor (NCT02070744)
- 2018-04-13Results posted on the registry: Vertex Pharmaceuticals Incorporated, VX-661 + Ivacaftor (NCT01531673)
- 2018-04-02Results posted on the registry: Novartis Pharmaceuticals, QBW251 + Placebo (NCT02449018)
- 2018-03-09Phase 3 first posted: Vertex Pharmaceuticals Incorporated, VX-659/TEZ/IVA + TEZ/IVA (NCT03460990)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision