Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 15:30 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Nintedanib as Switch Maintenance Treatment of Pleural Malignant Mesothelioma
NCT02863055 · European Organisation for Research and Treatment of Cancer - EORTC · PHASE2 · terminated · last registry update 2025-09-19 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “lack of scientific relevance (change in the treatment landscape) and poor recruitment” | – | Registry record, European Organisation for Research and Treatment of Cancer - EORTC |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against PDGFRB within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-09-11Results posted on the registry: Memorial Sloan Kettering Cancer Center, Regorafenib (NCT02023333)
- 2026-08-31Results posted on the registry: University of Texas Southwestern Medical Center, a drug against PDGFRB (NCT02956798)
- 2026-08-26Results posted on the registry: Bristol-Myers Squibb, Nivolumab-relatlimab FDC + Regorafenib (NCT05328908)
- 2026-08-26Also stopped (terminated): Bristol-Myers Squibb, Nivolumab-relatlimab FDC + Regorafenib (NCT05328908)
- 2026-08-25Also stopped (terminated): Association of Urologic Oncology (AUO), Sunitinib + Placebo (NCT01216371)
- 2026-08-13Results posted on the registry: PureTech, Nintedanib 150 MG [Ofev] (NCT06717100)
- 2026-07-28Phase 3 first posted: Sichuan Baili Pharmaceutical Co., Ltd., BL-M07D1 + Regorafenib (NCT07730489)
- 2026-07-23Phase 3 first posted: Innovent Biologics (Suzhou) Co. Ltd., IBI363 + bevacizumab + Investigator's choice of therapy (NCT07722494)
- 2026-07-22Results posted on the registry: Amgen, Sotorasib + Panitumumab (NCT05198934)
- 2026-07-20Phase 3 first posted: The Second Affiliated Hospital of Kunming Medical University, a drug against PDGFRB (NCT07712848)
- 2026-07-20Results posted on the registry: Academic and Community Cancer Research United, Durvalumab + Regorafenib (NCT05194293)
- 2026-07-14Results posted on the registry: Jennerex Biotherapeutics, JX-594 + Sorafenib (NCT01171651)
- 2026-07-09Results posted on the registry: Eli Lilly and Company, Pegilodecakin + Paclitaxel or Docetaxel and Carboplatin or Cisplatin (NCT02009449)
- 2026-07-08Results posted on the registry: Jennerex Biotherapeutics, JX-594 recombinant vaccina GM-CSF (NCT01387555)
- 2026-07-06Results posted on the registry: Syndax Pharmaceuticals, Revumenib + Chemotherapy (NCT05731947)
- 2026-07-06Also stopped (terminated): Syndax Pharmaceuticals, Revumenib + Chemotherapy (NCT05731947)
- 2026-06-16Results posted on the registry: University of Southern California, Pembrolizumab + Regorafenib (NCT03657641)
- 2026-06-15Also stopped (withdrawn): University of Miami, Regorafenib (NCT06902246)
- 2026-06-10Results posted on the registry: Australasian Gastro-Intestinal Trials Group, Regorafenib + Nivolumab (NCT04879368)
- 2026-05-29Also stopped (terminated): Sarit Assouline, Asciminib + Imatinib (NCT05413915)
- 2026-05-20Also stopped (terminated): Massachusetts General Hospital, Tivozanib + Enzalutamide (NCT01885949)
- 2026-05-13Phase 3 first posted: GlaxoSmithKline, Velzatinib + Imatinib (NCT07585266)
- 2026-05-06Also stopped (suspended): AB Science, Placebo + Masitinib (4.5) (NCT05441488)
- 2026-04-30Results posted on the registry: Icahn School of Medicine at Mount Sinai, Nintedanib + Placebo (NCT04619680)
- 2026-04-15Phase 3 first posted: Second Affiliated Hospital, Zhejiang University, School of Medicine, Tofacitinib + Imatinib (NCT07530367)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision