Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 22:50 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Phase 2 Study of Glesatinib, Sitravatinib or Mocetinostat in Combination With Nivolumab in Non-Small Cell Lung Cancer
NCT02954991 · Mirati Therapeutics Inc. · PHASE2 · terminated · last registry update 2024-04-22 · Non-small cell lung cancer · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “This study was terminated as a result of Sponsor portfolio reprioritization.” | Open Targets' class: business administrative | Registry record, Mirati Therapeutics Inc. |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against MET in non-small cell lung cancer within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-04-16Results posted on the registry: Janssen Research & Development, LLC, Lazertinib + Amivantamab (NCT04988295)
- 2025-04-03Phase 3 first posted: Intergroupe Francophone de Cancerologie Thoracique, Tepotinib + Pemetrexed (Alimta) (NCT06908993)
- 2025-03-26Results posted on the registry: Novartis Pharmaceuticals, capmatinib (NCT04926831)
- 2025-02-19Results posted on the registry: Takeda, Brigatinib + Alectinib (NCT03596866)
- 2025-02-10Also stopped (terminated): Blueprint Medicines Corporation, BLU-451 + Carboplatin (NCT05241873)
- 2025-01-30Results posted on the registry: Novartis Pharmaceuticals, Capmatinib + Docetaxel (NCT04427072)
- 2024-11-08Results posted on the registry: Pfizer, Crizotinib (NCT03672643)
- 2024-11-08Also stopped (terminated): Pfizer, Crizotinib (NCT03672643)
- 2024-10-09Results posted on the registry: Janssen Research & Development, LLC, Amivantamab + Osimertinib (NCT04487080)
- 2024-10-09Also stopped (terminated): Novartis Pharmaceuticals, Capmatinib + Pembrolizumab (NCT04139317)
- 2024-10-09Also stopped (terminated): Novartis Pharmaceuticals, Spartalizumab + Capmatinib (NCT04323436)
- 2024-09-24Results posted on the registry: AstraZeneca, Osimertinib + Savolitinib + Savolitinib + Placebo (NCT04606771)
- 2024-08-26Phase 3 first posted: Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd., a drug against MET (NCT06569420)
- 2024-08-21Phase 3 first posted: Nuvation Bio Inc., Taletrectinib + Crizotinib (NCT06564324)
- 2024-06-26Also stopped (withdrawn): AbbVie, Telisotuzumab Vedotin + Osimertinib (NCT06093503)
- 2024-06-17Also stopped (withdrawn): Timothy Burns, MD, PHD, Capmatinib (NCT05567055)
- 2024-06-11Also stopped (terminated): Collin Blakely, Capmatinib + Trametinib (NCT05435846)
- 2024-06-04Results posted on the registry: EMD Serono Research & Development Institute, Inc., Tepotinib + Osimertinib (NCT03940703)
- 2024-05-29Results posted on the registry: Janssen Research & Development, LLC, Amivantamab + Pemetrexed (NCT04538664)
- 2024-04-26Also stopped (terminated): Suzhou Zelgen Biopharmaceuticals Co.,Ltd, Alkotinib Capsules (NCT04211922)
- 2024-03-20Results posted on the registry: Novartis Pharmaceuticals, Capmatinib (NCT02414139)
- 2024-03-05Also stopped (terminated): Novartis Pharmaceuticals, Capmatinib + Osimertinib (NCT04816214)
- 2024-02-12Phase 3 first posted: Shouyao Holdings (Beijing) Co. LTD, SY-3505 Capsules + Crizotinib Capsules (NCT06254599)
- 2024-02-08Results posted on the registry: Novartis Pharmaceuticals, Capmatinib + Pembrolizumab (NCT04139317)
- 2024-02-06Results posted on the registry: Novartis Pharmaceuticals, Spartalizumab + Capmatinib (NCT04323436)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision