Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 07:06 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Study to Evaluate the Safety and Efficacy of CTP-656 in Patients With Cystic Fibrosis With CFTR Gating Mutations
NCT02971839 · Vertex Pharmaceuticals Incorporated · PHASE2 · terminated · last registry update 2020-08-26 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Decision by Sponsor.” | – | Registry record, Vertex Pharmaceuticals Incorporated |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against CFTR within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2021-08-18Results posted on the registry: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + TEZ/IVA (NCT04105972)
- 2021-07-29Results posted on the registry: Parion Sciences, VX-371 + HS + Hypertonic saline (NCT02709109)
- 2021-07-20Phase 3 first posted: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT04969224)
- 2021-07-02Results posted on the registry: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT04058353)
- 2021-04-22Results posted on the registry: Vertex Pharmaceuticals Incorporated, VX-659 + TEZ/IVA (NCT03224351)
- 2021-01-28Results posted on the registry: Vertex Pharmaceuticals Incorporated, VX-152 + TEZ/IVA (NCT02951195)
- 2020-12-30Also stopped (terminated): Novartis Pharmaceuticals, Placebo + QBW251 (NCT02190604)
- 2020-10-22Phase 3 first posted: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT04599465)
- 2020-09-29Results posted on the registry: University of California, San Francisco, ivacaftor + Placebo (NCT01784419)
- 2020-09-11Phase 3 first posted: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT04545515)
- 2020-09-04Phase 3 first posted: Napo Pharmaceuticals, Inc., Crofelemer 125 MG [Mytesi] + Placebo (NCT04538625)
- 2020-09-03Phase 3 first posted: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT04537793)
- 2020-09-03Results posted on the registry: Bausch Health Americas, Inc., Crofelemer 125 mg + Crofelemer 250 mg (NCT00547898)
- 2020-08-28Results posted on the registry: Vertex Pharmaceuticals Incorporated, TEZ + IVA (NCT02951182)
- 2020-08-17Results posted on the registry: Bausch Health Americas, Inc., Crofelemer (NCT01374490)
- 2020-08-07Results posted on the registry: Vertex Pharmaceuticals Incorporated, LUM/IVA (NCT03125395)
- 2020-06-16Results posted on the registry: Vertex Pharmaceuticals Incorporated, TEZ/IVA + IVA (NCT02565914)
- 2020-05-19Results posted on the registry: Vertex Pharmaceuticals Incorporated, VX-445/TEZ/IVA + IVA (NCT03525444)
- 2020-04-27Phase 3 first posted: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT04362761)
- 2020-04-20Phase 3 first posted: Vertex Pharmaceuticals Incorporated, ELX/TEZ/IVA + IVA (NCT04353817)
- 2020-04-08Also stopped (terminated): University Hospital, Antwerp, Orkambi (NCT03956589)
- 2020-03-26Results posted on the registry: University of Alabama at Birmingham, Ataluren (NCT03256968)
- 2020-03-13Results posted on the registry: Vertex Pharmaceuticals Incorporated, VX-659/TEZ/IVA + IVA (NCT03447249)
- 2020-02-11Results posted on the registry: Vertex Pharmaceuticals Incorporated, TEZ/IVA + IVA (NCT03559062)
- 2020-02-05Results posted on the registry: Vertex Pharmaceuticals Incorporated, VX-659/TEZ/IVA + IVA (NCT03633526)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision