Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 15:56 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Testing the Addition of KRT-232 (AMG 232) to Usual Chemotherapy for Relapsed Multiple Myeloma
NCT03031730 · National Cancer Institute (NCI) · PHASE1 · terminated · last registry update 2026-02-10 · Multiple myeloma · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Inadequate accrual rate” | Open Targets' class: insufficient enrollment | Registry record, National Cancer Institute (NCI) |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against PSMD1 in multiple myeloma within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-11-02Results posted on the registry: Mayo Clinic, Carfilzomib + Daratumumab (NCT05497804)
- 2026-11-02Results posted on the registry: Joseph Tuscano, Clarithromycin + Dexamethasone (NCT02542657)
- 2026-09-29Results posted on the registry: Hoffmann-La Roche, Forimtamig + Carfilzomib (NCT06055075)
- 2026-09-29Also stopped (terminated): Hoffmann-La Roche, Forimtamig + Carfilzomib (NCT06055075)
- 2026-09-15Results posted on the registry: Academic and Community Cancer Research United, Carfilzomib + Daratumumab (NCT04756401)
- 2026-08-19Phase 3 first posted: CellCentric Ltd., InoPd + Investigator's choice of SAT (NCT07772024)
- 2026-07-27Phase 3 first posted: AbbVie, Etentamig + Pomalidomide (NCT07728188)
- 2026-07-13Also stopped (suspended): Hackensack Meridian Health, Carfilzomib + Iberdomide (NCT05199311)
- 2026-05-29Results posted on the registry: Memorial Sloan Kettering Cancer Center, daratumumab + carfilzomib (NCT03290950)
- 2026-05-15Also stopped (withdrawn): Roswell Park Cancer Institute, Carfilzomib + Daratumumab and Recombinant Human Hyaluronidase (NCT07082270)
- 2026-05-13Also stopped (terminated): University Hospital, Caen, Ixazomib and Daratumumab (NCT03757221)
- 2026-05-04Also stopped (terminated): Takeda, Ixazomib + Lenalidomide (NCT03173092)
- 2026-04-29Phase 3 first posted: Hoffmann-La Roche, Cevostamab + Pomalidomide (NCT07555938)
- 2026-03-20Results posted on the registry: Celgene, CC-220 + Dexamethasone (NCT02773030)
- 2026-03-06Results posted on the registry: University of Colorado, Denver, Selinexor + Pomalidomide (NCT04925193)
- 2026-02-06Phase 3 first posted: AstraZeneca, AZD0120 + Daratumumab (NCT07391657)
- 2026-01-29Also stopped (terminated): Teva Branded Pharmaceutical Products R&D LLC, Modakafusp alfa + Lenalidomide (NCT05556616)
- 2026-01-22Results posted on the registry: University of Chicago, Ixazomib Citrate + Lenalidomide (NCT02389517)
- 2026-01-05Also stopped (terminated): Universitätsklinikum Hamburg-Eppendorf, Allogeneic Stem Cells + carfilzomib/lenalidomide/dexamethasone (KRD) (NCT05675319)
- 2025-11-20Results posted on the registry: Memorial Sloan Kettering Cancer Center, Carfilzomib + Lenalidomide (NCT02937571)
- 2025-10-30Phase 3 first posted: Regeneron Pharmaceuticals, Linvoseltamab + Carfilzomib (NCT07222761)
- 2025-10-21Also stopped (terminated): University of California, San Diego, Ixazomib + Pomalidomide (NCT03590652)
- 2025-10-07Also stopped (terminated): University of Pennsylvania, Tasquinimod + IRd chemotherapy (NCT04405167)
- 2025-09-10Results posted on the registry: University of Chicago, Elotuzumab + Carfilzomib (NCT02969837)
- 2025-08-06Results posted on the registry: Teva Branded Pharmaceutical Products R&D LLC, Modakafusp alfa + Lenalidomide (NCT05556616)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision