Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 04:03 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Optimal Antithrombotic Therapy in Ischemic Stroke Patients with Non-Valvular Atrial Fibrillation and Atherothrombosis
NCT03062319 · National Hospital Organization Osaka National Hospital · PHASE4 · terminated · last registry update 2024-12-27 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “The trial was terminated at the planned interim analysis for futility on July 18, 2023.” | – | Registry record, National Hospital Organization Osaka National Hospital |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against F10 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-12-10Also stopped (terminated): CSL Behring, BE1116 + Placebo (NCT05568888)
- 2025-11-14Phase 3 first posted: McMaster University, rivaroxaban and ASA + Low-molecular weight heparin (NCT07228663)
- 2025-11-10Results posted on the registry: CSL Behring, BE1116 + Placebo (NCT05568888)
- 2025-11-06Results posted on the registry: Pfizer, Standard of Care FIX Replacement therapy + Standard of Care FVIII Replacement therapy (NCT03587116)
- 2025-11-04Also stopped (withdrawn): Brian O'Neill MD, Market approved oral anticoagulation (OAC), such as warfarin (Coumadin), dabigatran (Pradaxa), rivaroxaban (Xarelto), apixiban (Eliquis), edoxaban (Savaysa), or betrixaban (Bevyxxa) (NCT04684212)
- 2025-10-02Phase 3 first posted: Rennes University Hospital, Anticoagulant treatment Rivaroxaban (NCT07202897)
- 2025-09-30Results posted on the registry: Brigham and Women's Hospital, Apixaban 2.5 MG + Placebo oral tablet (NCT04168203)
- 2025-09-08Phase 3 first posted: University of Birmingham, Apixaban (NCT07160686)
- 2025-09-02Results posted on the registry: Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc., Ciraparantag + Placebo (NCT03172910)
- 2025-09-02Results posted on the registry: Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc., Ciraparantag + Placebo (NCT03288454)
- 2025-08-15Results posted on the registry: Octapharma, Octaplex + Frozen Plasma Product, Human (NCT05523297)
- 2025-07-30Phase 3 first posted: CSL Behring, BE1116 + FFP (NCT07094087)
- 2025-07-30Results posted on the registry: Anthos Therapeutics, Inc., Abelacimab + Rivaroxaban (NCT04755283)
- 2025-07-16Results posted on the registry: Regeneron Pharmaceuticals, REGN9933 + Enoxaparin (NCT05618808)
- 2025-06-22Results posted on the registry: Stanford University, Apixaban 2.5 MG Oral Tablet + Enoxaparin 40Mg/0.4mL Prefilled Syringe (NCT04504318)
- 2025-06-22Also stopped (terminated): Imperial College London, Best medical therapy (NCT05622500)
- 2025-06-18Results posted on the registry: Fadoi Foundation, Italy, Apixaban + Dalteparin (NCT03045406)
- 2025-06-15Also stopped (terminated): Montreal Heart Institute, Rivaroxaban (NCT02387229)
- 2025-06-11Phase 3 first posted: Regeneron Pharmaceuticals, REGN7508 + Apixaban (NCT07015905)
- 2025-06-05Results posted on the registry: Takeda, a drug against F10 (NCT05437211)
- 2025-06-04Phase 3 first posted: University of Vermont, Apixaban 2.5 mg twice daily + Apixaban 5 mg once daily (NCT07005024)
- 2025-05-31Phase 3 first posted: Hoffmann-La Roche, Emicizumab + von Willebrand Factor (VWF) Concentrates (NCT06998524)
- 2025-05-11Phase 3 first posted: Ottawa Hospital Research Institute, Full dose rivaroxaban + Low dose rivaroxaban (NCT06965998)
- 2025-05-08Phase 3 first posted: Kedrion S.p.A., Coagadex(R) (NCT06963216)
- 2025-05-04Results posted on the registry: CytoSorbents, Inc, a drug against F10 (NCT05093504)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision