Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 22:50 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Study to Evaluate Vadadustat for Anemia in Subjects With Dialysis-Dependent Chronic Kidney Disease (DD-CKD) Who Are Hyporesponsive to Erythropoiesis Stimulating Agents
NCT03140722 · Akebia Therapeutics · PHASE2 · terminated · last registry update 2021-02-21 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Revised study design.” | – | Registry record, Akebia Therapeutics |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against EGLN1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2022-02-10Results posted on the registry: Kyntra Bio, Roxadustat (NCT01244763)
- 2022-01-11Results posted on the registry: Kyntra Bio, Roxadustat + Epoetin Alfa (NCT01147666)
- 2021-12-03Results posted on the registry: GlaxoSmithKline, Daprodustat + rhEPO (NCT02879305)
- 2021-11-19Results posted on the registry: Kyntra Bio, Roxadustat + Placebo (NCT00761657)
- 2021-11-03Results posted on the registry: GlaxoSmithKline, Daprodustat (GSK1278863) + Placebo (NCT03409107)
- 2021-10-29Results posted on the registry: Kyntra Bio, Epoetin Alfa + Roxadustat (NCT02273726)
- 2021-10-20Results posted on the registry: GlaxoSmithKline, Daprodustat + Darbepoetin alfa (NCT03029208)
- 2021-10-19Phase 3 first posted: Akebia Therapeutics, Vadadustat (NCT05082584)
- 2021-10-19Phase 3 first posted: Akebia Therapeutics, vadadustat (NCT05082571)
- 2021-10-01Results posted on the registry: Kyntra Bio, Roxadustat + Placebo (NCT01750190)
- 2021-10-01Results posted on the registry: Kyntra Bio, Roxadustat + Epoetin Alfa (NCT02052310)
- 2021-10-01Results posted on the registry: Kyntra Bio, Roxadustat + Oral Iron (NCT01414075)
- 2021-10-01Results posted on the registry: Kyntra Bio, Roxadustat (NCT01630889)
- 2021-07-21Results posted on the registry: GlaxoSmithKline, Daprodustat + Darbepoetin alfa (NCT03446612)
- 2021-07-12Results posted on the registry: GlaxoSmithKline, Daprodustat tablets + Matching placebo tablets (NCT03400033)
- 2021-07-06Results posted on the registry: Tanabe Pharma Corporation, MT-6548 (NCT03402386)
- 2021-06-14Phase 3 first posted: Mao Jianhua, Roxadustat (NCT04925011)
- 2021-06-03Results posted on the registry: GlaxoSmithKline, Daprodustat + Epoetin alfa (NCT03029247)
- 2021-05-18Results posted on the registry: Tanabe Pharma Corporation, MT-6548 + Iron supplement A (NCT03645863)
- 2021-05-07Results posted on the registry: Tanabe Pharma Corporation, MT-6548 (NCT03461146)
- 2021-04-12Results posted on the registry: Tanabe Pharma Corporation, MT-6548 + Darbepoetin alfa (NCT03329196)
- 2021-04-12Results posted on the registry: Tanabe Pharma Corporation, MT-6548 + Darbepoetin alfa (NCT03439137)
- 2021-04-08Results posted on the registry: Akebia Therapeutics, Vadadustat + Placebo (NCT03054350)
- 2021-04-08Results posted on the registry: Akebia Therapeutics, Vadadustat + Placebo (NCT03054337)
- 2021-03-29Results posted on the registry: Astellas Pharma Europe B.V., Roxadustat + Darbepoetin alfa (NCT02021318)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision