Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 01:14 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Combination Latency Reversal With High Dose Disulfiram Plus Vorinostat in HIV-infected Individuals on ART
NCT03198559 · University of Melbourne · PHASE1/PHASE2 · terminated · last registry update 2024-02-09 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “A re-evaluation of research risks to participants were greater than originally anticipated” | – | Registry record, University of Melbourne |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against ALDH2 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-01-07Also stopped (terminated): Mayo Clinic, Chemotherapy + Disulfiram (NCT02671890)
- 2024-10-03Also stopped (terminated): Wake Forest University Health Sciences, Disulfiram + Temozolomide (NCT03363659)
- 2023-10-18Results posted on the registry: HonorHealth Research Institute, nab-paclitaxel (Abraxane)/gemcitabine (Gemzar) Protocol Plus Disulfiram/Copper Gluconate + FOLFIRINOX regimen Plus Disulfiram/Copper Gluconate (NCT03714555)
- 2023-10-18Also stopped (terminated): HonorHealth Research Institute, nab-paclitaxel (Abraxane)/gemcitabine (Gemzar) Protocol Plus Disulfiram/Copper Gluconate + FOLFIRINOX regimen Plus Disulfiram/Copper Gluconate (NCT03714555)
- 2023-10-06Also stopped (withdrawn): National Cancer Institute, Slovakia, Disulfiram + Vinorelbin (NCT04265274)
- 2023-09-13Results posted on the registry: University of California, San Francisco, Disulfiram + Placebo (NCT04485130)
- 2023-09-13Also stopped (terminated): University of California, San Francisco, Disulfiram + Placebo (NCT04485130)
- 2023-09-08Results posted on the registry: Wake Forest University Health Sciences, Disulfiram + Temozolomide (NCT03363659)
- 2023-08-30Results posted on the registry: University of New Mexico, disulfiram plus lorazepam (NCT00721526)
- 2023-07-19Results posted on the registry: Baylor College of Medicine, placebo + disulfiram (NCT00729300)
- 2023-06-05Results posted on the registry: Research Foundation for Mental Hygiene, Inc., Disulfiram (NCT03891667)
- 2023-03-13Also stopped (terminated): University of Utah, Disulfiram + Copper Gluconate (NCT04521335)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision