Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 22:50 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Study to Evaluate Three Times Per Week (TIW) Oral Dosing of Vadadustat for Anemia in Subjects With Dialysis-Dependent Chronic Kidney Disease (DD-CKD)
NCT03242967 · Akebia Therapeutics · PHASE3 · withdrawn · last registry update 2018-11-05 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Revised study design.” | – | Registry record, Akebia Therapeutics |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against EGLN1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2019-09-04Results posted on the registry: GlaxoSmithKline, Daprodustat (GSK1278863) (NCT03223337)
- 2019-08-19Results posted on the registry: GlaxoSmithKline, GSK1278863 + Placebo (NCT01831804)
- 2019-08-06Results posted on the registry: GlaxoSmithKline, Daprodustat 2 mg tablet + Daprodustat 4 mg tablet (NCT03493386)
- 2019-07-22Phase 3 first posted: JW Pharmaceutical, JTZ-951 + Darbepoetin Alfa (NCT04027517)
- 2019-06-28Also stopped (terminated): GlaxoSmithKline, 5 mg GSK1278863 (NCT01406340)
- 2019-03-18Results posted on the registry: GlaxoSmithKline, [14C]-GSK1278863 solution for IV infusion + [14C]-GSK1278863 oral solution (NCT03239522)
- 2019-03-11Results posted on the registry: GlaxoSmithKline, GSK1278863 (NCT02243306)
- 2018-08-24Phase 3 first posted: Tanabe Pharma Corporation, MT-6548 + Iron supplement A (NCT03645863)
- 2018-07-13Results posted on the registry: GlaxoSmithKline, GSK1278863 + Iron (NCT02829320)
- 2018-06-01Phase 3 first posted: Bayer, Molidustat (BAY85-3934) + Darbepoetin alfa (NCT03543657)
- 2018-05-21Results posted on the registry: GlaxoSmithKline, GSK1278863 + GSK1278863 matching Placebo (NCT02689206)
- 2018-03-09Phase 3 first posted: Tanabe Pharma Corporation, MT-6548 (NCT03461146)
- 2018-02-20Phase 3 first posted: Tanabe Pharma Corporation, MT-6548 + Darbepoetin alfa (NCT03439137)
- 2018-02-12Results posted on the registry: GlaxoSmithKline, GSK1278863 + Placebo (NCT02019719)
- 2018-02-01Phase 3 first posted: Bayer, Molidustat (BAY85-3934) (NCT03418168)
- 2018-01-24Phase 3 first posted: GlaxoSmithKline, Daprodustat (GSK1278863) + Placebo (NCT03409107)
- 2018-01-18Phase 3 first posted: Tanabe Pharma Corporation, MT-6548 (NCT03402386)
- 2018-01-17Phase 3 first posted: GlaxoSmithKline, Daprodustat tablets + Matching placebo tablets (NCT03400033)
- 2017-12-07Results posted on the registry: GlaxoSmithKline, GSK1278863 + Placebo (NCT01920594)
- 2017-11-22Phase 3 first posted: Bayer, Molidustat (BAY85-3934) + Darbepoetin alfa (NCT03350347)
- 2017-11-22Phase 3 first posted: Bayer, Molidustat (BAY85-3934) (NCT03351166)
- 2017-11-22Phase 3 first posted: Bayer, Molidustat (BAY85-3934) + Darbepoetin alfa (NCT03350321)
- 2017-11-09Results posted on the registry: GlaxoSmithKline, GSK1278863 (NCT01587898)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision