Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 00:39 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Safety and Tolerability of Perampanel in Amyotrophic Lateral Sclerosis Patients
NCT03377309 · American University of Beirut Medical Center · PHASE2 · terminated · last registry update 2021-09-01 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Study halted due to adverse events” | – | Registry record, American University of Beirut Medical Center |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against GRIA4 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2022-07-13Results posted on the registry: University of Colorado, Denver, Topiramate (NCT03335163)
- 2022-06-27Also stopped (withdrawn): Assistance Publique Hopitaux De Marseille, Perampanel + conventional antiepileptic treatment (NCT03636958)
- 2022-05-16Results posted on the registry: Eisai Inc., Perampanel (NCT03288129)
- 2022-03-09Results posted on the registry: Eisai Inc., Placebo + Perampanel (NCT02834793)
- 2022-03-09Also stopped (terminated): Eisai Inc., Placebo + Perampanel (NCT02834793)
- 2022-03-03Also stopped (terminated): University of Maryland, Baltimore, Topiramate + Placebo (NCT01408641)
- 2022-03-02Phase 3 first posted: University of Southern Denmark, Rapid sedation (NCT05263674)
- 2022-01-27Phase 3 first posted: Eurofarma Laboratorios S.A., ADF1 Group Eurofarma drug association of Sibutramine IR 15mg / Topiramate XR 75mg + ADF2 Group Eurofarma drug association of Sibutramine IR 15mg / Topiramate XR 100mg (NCT05209984)
- 2021-12-08Results posted on the registry: University of Arizona, Perampanel Oral Tablet (NCT03457129)
- 2021-08-09Results posted on the registry: Novartis Pharmaceuticals, Erenumab + Topiramate (NCT03828539)
- 2021-06-21Results posted on the registry: University of California, San Francisco, Topiramate + placebo (NCT01749215)
- 2021-06-18Results posted on the registry: Novo Nordisk A/S, Medication for chronic weight management (Rx) (NCT03799198)
- 2021-06-09Results posted on the registry: University of Iowa, Metformin + Orlistat (NCT01351753)
- 2021-05-17Results posted on the registry: Janssen Research & Development, LLC, Topiramate + Levetiracetam (NCT02201251)
- 2021-04-23Results posted on the registry: St. Louis University, nortriptyline + Topiramate (NCT02169830)
- 2021-04-23Also stopped (terminated): St. Louis University, nortriptyline + Topiramate (NCT02169830)
- 2021-02-21Results posted on the registry: University of Pennsylvania, Topiramate + Inactive Placebo (NCT02371889)
- 2021-01-29Results posted on the registry: Woman's, Exenatide once weekly (EQW ) + Dapagliflozin (DAPA) (NCT02635386)
- 2021-01-05Results posted on the registry: Eisai Co., Ltd., Perampanel + Perampanel (NCT03754582)
- 2020-12-17Also stopped (withdrawn): University of South Alabama, propranolol + zonisamide (NCT00777218)
- 2020-11-16Also stopped (withdrawn): Yale University, Topiramate + lamotrigine (NCT00571246)
- 2020-10-14Results posted on the registry: University of California, San Francisco, Topiramate + Placebo (NCT01750268)
- 2020-09-17Results posted on the registry: Brown University, Topiramate + Placebo (NCT01641445)
- 2020-09-16Results posted on the registry: Brown University, Topiramate + Placebo (NCT01110434)
- 2020-09-02Also stopped (terminated): McMaster University, Topiramate + Placebo (NCT00182455)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision