Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 00:41 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
A Trial of Doxycycline vs. Standard Supportive Therapy in Newly-diagnosed Cardiac AL Amyloidosis Patients Undergoing Bortezomib-based Therapy
NCT03474458 · Fondazione IRCCS Policlinico San Matteo di Pavia · PHASE2/PHASE3 · terminated · last registry update 2024-07-11 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “difficulty in recruitment” | – | Registry record, Fondazione IRCCS Policlinico San Matteo di Pavia |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against MMP7 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-06-22Results posted on the registry: PolyPid Ltd., D-PLEX + Standard of Care (SoC) (NCT04233424)
- 2024-12-03Results posted on the registry: Journey Medical Corporation, DFD-29 + Doxycycline (NCT05296629)
- 2024-12-03Results posted on the registry: Journey Medical Corporation, DFD-29 + Doxycycline (NCT05343455)
- 2024-10-26Also stopped (terminated): University of Washington, Lefamulin + Doxycycline (NCT05111002)
- 2024-10-16Results posted on the registry: University of Washington, Lefamulin + Doxycycline (NCT05111002)
- 2024-07-12Results posted on the registry: University of California, San Francisco, Doxycycline Hyclate Delayed-Release 200 mg (NCT03980223)
- 2024-07-10Results posted on the registry: University of Washington, Doxycycline (NCT04050540)
- 2024-07-03Also stopped (withdrawn): University of California, Davis, Rituximab combined with Omalizumab (NCT04128176)
- 2024-06-07Phase 3 first posted: Centre Hospitalier Universitaire de Nice, ISOtretinoin 5 MG + Topical cream (NCT06447480)
- 2024-04-05Phase 3 first posted: Assistance Publique Hopitaux De Marseille, Azithromycin + Ceftriaxone (NCT06349122)
- 2024-01-23Results posted on the registry: Sorlandet Hospital HF, Doxycycline + Placebo (NCT02553473)
- 2023-10-26Phase 3 first posted: Ain Shams University, Vonoprazan (NCT06101420)
- 2023-08-02Phase 3 first posted: Lao-Oxford-Mahosot Hospital Wellcome Trust Research Unit, Doxycyclin + Azithromycin (NCT05972772)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision