Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 19:12 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Safety Extension Trial of Inhaled Molgramostim in Autoimmune Pulmonary Alveolar Proteinosis
NCT03482752 · Savara Inc. · PHASE3 · terminated · last registry update 2024-07-03 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “SAV006-03 was initiated before the evaluation of the IMPALA study (NCT02702180) results. Considering these results and authority advice there would not be adequate efficacy and safety data from SAV006-03 and the study was terminated.” | – | Registry record, Savara Inc. |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against CSF3R within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-06-12Results posted on the registry: National Cancer Institute (NCI), Brentuximab Vedotin + Dacarbazine (NCT03907488)
- 2025-06-05Results posted on the registry: National Cancer Institute (NCI), Rituximab + Conditioning chemotherapy (NCT02356159)
- 2025-05-30Results posted on the registry: St. Jude Children's Research Hospital, COPAD + COP, COPD M3, CYM (NCT01046825)
- 2025-05-29Results posted on the registry: Gilead Sciences, Magrolimab + Rituximab (NCT02953509)
- 2025-05-29Also stopped (terminated): Gilead Sciences, Magrolimab + Rituximab (NCT02953509)
- 2025-05-23Results posted on the registry: M.D. Anderson Cancer Center, DS-1594b + Azacitidine (NCT04752163)
- 2025-05-23Also stopped (terminated): M.D. Anderson Cancer Center, DS-1594b + Azacitidine (NCT04752163)
- 2025-05-11Results posted on the registry: University of Chicago, Carboplatin + Paclitaxel (NCT03944915)
- 2025-05-01Results posted on the registry: M.D. Anderson Cancer Center, Filgrastim-sndz + Melphalan Hydrochloride (NCT03417284)
- 2025-04-23Results posted on the registry: Stanford University, GCSF (NCT04514692)
- 2025-04-23Also stopped (terminated): Stanford University, GCSF (NCT04514692)
- 2025-04-20Results posted on the registry: National Cancer Institute (NCI), Obinutuzumab + Prednisone (NCT05211336)
- 2025-04-20Results posted on the registry: EVIVE Biotechnology, F-627 + GRAN® (NCT04174599)
- 2025-04-01Also stopped (terminated): Emory University, G-CSF, GM-CSF administered at extremities + G-CSF and GMCSF administered at abdomen (NCT00646763)
- 2025-02-04Also stopped (terminated): Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, RIC alloBMT w PTCy in refractory SSc (NCT05298358)
- 2025-01-22Results posted on the registry: National Cancer Institute (NCI), Ibrutinib + Steroid pulse (prednisone) (NCT04294641)
- 2025-01-14Results posted on the registry: Astellas Pharma Inc, Gilteritinib + Cytarabine (NCT03182244)
- 2025-01-07Results posted on the registry: Fred Hutchinson Cancer Center, Anti-Thymocyte Globulin + Cyclophosphamide (NCT01413100)
- 2024-12-06Results posted on the registry: Memorial Sloan Kettering Cancer Center, melphalan + fludarabine (NCT02880293)
- 2024-12-05Phase 3 first posted: Merck Sharp & Dohme LLC, Zilovertamab vedotin + Rituximab (NCT06717347)
- 2024-12-02Phase 3 first posted: Kexing Biopharm Co., Ltd., PEG-G-CSF injection (Kexing Biopharmaceutical Co., Ltd.) + PEG-G-CSF injection (Neulasta®,Amgen Europe B.V.) (NCT06711523)
- 2024-11-29Results posted on the registry: National Heart, Lung, and Blood Institute (NHLBI), Alemtuzumab + Sirolimus (NCT02105766)
- 2024-10-24Results posted on the registry: Georgetown University, mFOLFIRINOX (NCT03885284)
- 2024-10-21Results posted on the registry: University of Illinois Chicago, Melphalan + Filgrastim (G-CSF) (NCT02043847)
- 2024-09-24Results posted on the registry: Medical College of Wisconsin, Busulfan + Fludarabine (NCT02766465)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision