Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 06:00 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Febuxostat for Tumor Lysis Syndrome Prevention in Hematological Malignancies of Paediatric Patients and Adults
NCT03605212 · Menarini Group · PHASE1/PHASE2 · terminated · last registry update 2021-06-03 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “The study was stopped as per EMA waiver granted on 20July2018.” | – | Registry record, Menarini Group |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against XDH within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2022-01-31Results posted on the registry: AstraZeneca, Verinurad + Placebo (NCT04256629)
- 2022-01-11Results posted on the registry: VA Office of Research and Development, allopurinol capsule, 100-800 mg by mouth once daily + febuxostat tablet 40-120 mg by mouth once daily (NCT02579096)
- 2021-11-05Phase 3 first posted: University Hospital, Rouen, Adenuric (NCT05109936)
- 2021-11-04Results posted on the registry: Ironwood Pharmaceuticals, Inc., Lesinurad + XOI (NCT03226899)
- 2021-11-04Also stopped (terminated): Ironwood Pharmaceuticals, Inc., Lesinurad + XOI (NCT03226899)
- 2021-08-16Phase 3 first posted: Eisai Co., Ltd., Dotinurad + Febuxostat (NCT05007392)
- 2021-07-09Phase 3 first posted: Jiangsu HengRui Medicine Co., Ltd., SHR4640 + Allopurinol (NCT04956432)
- 2021-05-27Results posted on the registry: Virginia Commonwealth University, Allopurinol (NCT03865407)
- 2021-05-27Also stopped (terminated): Virginia Commonwealth University, Allopurinol (NCT03865407)
- 2021-04-13Results posted on the registry: Masonic Cancer Center, University of Minnesota, Allopurinol + Keppra (NCT01685411)
- 2021-04-13Also stopped (terminated): Masonic Cancer Center, University of Minnesota, Allopurinol + Keppra (NCT01685411)
- 2020-11-20Results posted on the registry: Alessandro Doria, Allopurinol + Placebo (NCT02017171)
- 2020-10-28Results posted on the registry: TWi Biotechnology, Inc., Placebo + AC-201 (NCT02287818)
- 2020-09-29Also stopped (terminated): Masonic Cancer Center, University of Minnesota, Infusion of Treg (NCT02991898)
- 2020-08-14Results posted on the registry: University of Wisconsin, Madison, Losartan + Allopurinol (NCT01637623)
- 2020-07-24Results posted on the registry: Masonic Cancer Center, University of Minnesota, Infusion of Treg (NCT02991898)
- 2020-06-23Results posted on the registry: University of California, San Francisco, Allopurinol (NCT02956278)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision