Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 15:53 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
A Study of Bempegaldesleukin (NKTR-214: BEMPEG) in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib or Cabozantinib Monotherapy) for Advanced Metastatic Renal Cell Carcinoma (RCC)
NCT03729245 · Nektar Therapeutics · PHASE3 · terminated · last registry update 2023-04-11 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Sponsor decision” | – | Registry record, Nektar Therapeutics |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against CSF1R within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2024-03-13Results posted on the registry: University of Washington, Sirolimus Albumin-bound Nanoparticles + Pazopanib hydrochloride (NCT03660930)
- 2024-03-13Also stopped (terminated): M.D. Anderson Cancer Center, Bevacizumab + Emactuzumab (NCT02923739)
- 2024-03-04Also stopped (terminated): OHSU Knight Cancer Institute, Abemaciclib + Abiraterone (NCT03878524)
- 2024-02-28Results posted on the registry: M.D. Anderson Cancer Center, Azacitidine + Cytarabine (NCT01892371)
- 2024-02-23Phase 3 first posted: Gossamer Bio USA, Inc., Seralutinib (NCT06274801)
- 2024-02-16Phase 3 first posted: Incyte Biosciences Japan GK, INCA034176 (NCT06263478)
- 2024-02-16Phase 3 first posted: Intensity Therapeutics, Inc., INT230-6 + Eribulin (NCT06263231)
- 2024-02-09Also stopped (terminated): Jiangsu HengRui Medicine Co., Ltd., Famitinib capsules + Sunitinib Capsules (NCT04409223)
- 2024-01-05Also stopped (terminated): National Eye Institute (NEI), Sunitinib Malate (NCT00673816)
- 2024-01-02Results posted on the registry: Deciphera Pharmaceuticals, LLC, Ripretinib + Sunitinib (NCT03673501)
- 2023-12-05Also stopped (terminated): SCRI Development Innovations, LLC, CPX-351 + Quizartinib (NCT04209725)
- 2023-11-07Results posted on the registry: GB002, Inc., a wholly owned subsidiary of Gossamer Bio, Inc., GB002 (seralutinib) + Placebo (NCT04456998)
- 2023-10-10Results posted on the registry: M.D. Anderson Cancer Center, Bevacizumab + Emactuzumab (NCT02923739)
- 2023-09-21Results posted on the registry: Dartmouth-Hitchcock Medical Center, Sunitinib + Temsirolimus (NCT01517243)
- 2023-08-18Results posted on the registry: Yale University, APX005M + Cabiralizumab (NCT03502330)
- 2023-08-01Results posted on the registry: Daiichi Sankyo, Quizartinib (NCT04473664)
- 2023-07-07Phase 3 first posted: GB002, Inc., Placebo + Seralutinib (NCT05934526)
- 2023-04-27Results posted on the registry: Daiichi Sankyo Co., Ltd., Pexidartinib (NCT04488822)
- 2023-04-11Results posted on the registry: National Cancer Institute (NCI), AZD6244 + MK-2206 (NCT01306045)
- 2023-03-31Results posted on the registry: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Durvalumab + SNDX-6352 (NCT04301778)
- 2023-03-21Results posted on the registry: Novartis Pharmaceuticals, Pazopanib (NCT03200717)
- 2023-02-17Phase 3 first posted: Deciphera Pharmaceuticals, LLC, Ripretinib + Sunitinib (NCT05734105)
- 2023-01-11Results posted on the registry: Daiichi Sankyo, Quizartinib dihydrochloride + 14C-Quizartinib solution for infusion (NCT04796831)
- 2023-01-10Phase 3 first posted: Exelixis, XL092 + Nivolumab (NCT05678673)
- 2022-10-12Also stopped (terminated): Ludwig Institute for Cancer Research, Chimeric monoclonal antibody cG250 + Sunitinib malate (NCT00520533)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision