Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 16:10 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
A Trial of Fedratinib in Subjects With DIPSS, Intermediate or High-Risk Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis and Previously Treated With Ruxolitinib
NCT03755518 · Celgene · PHASE3 · terminated · last registry update 2024-12-12 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Slow accrual.” | – | Registry record, Celgene |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against FLT3 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-12-11Results posted on the registry: Exelixis, Cabozantinib + Cabozantinib (NCT03755791)
- 2025-12-04Phase 3 first posted: Nanfang Hospital, Southern Medical University, Sorafenib (SORA) + Venetoclax (VEN) (NCT07264010)
- 2025-12-04Also stopped (terminated): H. Lee Moffitt Cancer Center and Research Institute, Fedratinib Pill (NCT05127174)
- 2025-11-17Also stopped (terminated): Medical College of Wisconsin, Pacritinib (NCT04635059)
- 2025-11-10Results posted on the registry: Boehringer Ingelheim, BI 836880 + Ezabenlimab (NCT03468426)
- 2025-11-05Results posted on the registry: University of Nebraska, Cytarabine + Decitabine (NCT03226418)
- 2025-10-23Also stopped (suspended): Mirror Biologics, Inc., AlloStim® immunotherapy + FOLFOX regimen (NCT05033522)
- 2025-10-21Phase 3 first posted: GlaxoSmithKline, IDRX-42 + Sunitinib (NCT07218926)
- 2025-10-14Results posted on the registry: BeiGene, Tislelizumab + Sorafenib (NCT03412773)
- 2025-10-02Phase 3 first posted: Nanfang Hospital, Southern Medical University, targeted drug (NCT07203352)
- 2025-09-23Also stopped (terminated): Jiangsu HengRui Medicine Co., Ltd., Camrelizumab;Pemetrexed and Carboplatin; Famitinib; + Camrelizumab;Pemetrexed and Carboplatin;Placebo (NCT04619433)
- 2025-09-12Results posted on the registry: Astellas Pharma Global Development, Inc., gilteritinib + azacitidine (NCT02752035)
- 2025-09-10Phase 3 first posted: Peking University Cancer Hospital & Institute, Vorolanib Tablets+Everolimus + Sunitinib (NCT07165418)
- 2025-08-22Also stopped (terminated): Jiangsu HengRui Medicine Co., Ltd., SHR-1802+camrelizumab + famitinib (NCT05208177)
- 2025-08-06Also stopped (withdrawn): M.D. Anderson Cancer Center, Cladribine + Cytarabine (NCT06474663)
- 2025-05-15Phase 3 first posted: Ruijin Hospital, Decitabine + Sorafenib (BAY-43-9006),giritinib (NCT06972641)
- 2025-04-27Also stopped (withdrawn): Medical University of South Carolina, ABC294640 (NCT02939807)
- 2025-04-06Phase 3 first posted: Fudan University, Targeted therapy agents: SNF2 -adebrelimab + famitinib; SNF3 -fluzoparib; SNF4 -apatinib + Chemotherapy (wP-EC) (NCT06913777)
- 2025-03-30Results posted on the registry: Fundacion Clinic per a la Recerca Biomédica, Cabozantinib (NCT04316182)
- 2025-03-21Results posted on the registry: Gulam Manji, PLX3397 + sirolimus (NCT02584647)
- 2025-03-21Also stopped (terminated): Gulam Manji, PLX3397 + sirolimus (NCT02584647)
- 2025-03-19Results posted on the registry: National Cancer Institute (NCI), Sunitinib (NCT06390826)
- 2025-03-07Also stopped (terminated): Aptose Biosciences Inc., CG-806 (NCT04477291)
- 2025-03-03Results posted on the registry: Daiichi Sankyo Co., Ltd., Pexidartinib (NCT04703322)
- 2025-02-28Results posted on the registry: PrECOG, LLC., Gilteritinib + Midostaurin (NCT03836209)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision