OncoSignal
Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 20:03 UTC. Every row links to its source record.

Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time

A Study of Esketamine Nasal Spray Plus a New Standard-of-care Oral Antidepressant or Placebo Nasal Spray Plus a New Standard-of-care Oral Antidepressant in Adult and Elderly Participants With Treatment-resistant Depression

NCT03852160 · Janssen-Cilag International NV · PHASE3 · withdrawn · last registry update 2025-04-27 · Decision brief

No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.

What was said, and by whom

Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.

KindQuoteOur categorySource
Stated“New design was developed to better fit company strategy, a new study has replaced 5413541TRD3011 study”–Registry record, Janssen-Cilag International NV

Also happening at the time. Not shown to be a cause.

Registry events on other trials of drugs against GRIN1 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.

What is not public

  • Internal portfolio and board discussions
  • Unpublished trial data and interim analyses
  • Terms of any partner or licence decision