Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 06:53 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Denosumab in Combination With Enzalutamide in Progressive Metastatic Castrate-resistant Prostate Cancer and Bone Metastases.
NCT03869762 · Cancer Trials Ireland · PHASE2 · terminated · last registry update 2026-04-13 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Insufficient accrual” | – | Registry record, Cancer Trials Ireland |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against TNFSF11 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-10-27Results posted on the registry: Nami Safai Haeri, Denosumab + Zoledronic Acid (NCT05666310)
- 2026-10-23Also stopped (terminated): Swiss Cancer Institute, Denosumab (reduced dosing) + Denosumab (standard dosing) (NCT02051218)
- 2026-10-09Results posted on the registry: Washington University School of Medicine, Denosumab + Placebo (NCT04067726)
- 2026-09-08Also stopped (terminated): ETOP IBCSG Partners Foundation, Denosumab (NCT02129699)
- 2026-04-23Results posted on the registry: University of Alabama at Birmingham, DMAB Discontinuation and Switching (NCT04177940)
- 2026-02-10Results posted on the registry: Enzene Biosciences Ltd., ENZ215 + Prolia (NCT05405725)
- 2025-12-23Results posted on the registry: Enzene Biosciences Ltd., ENZ215 + EU Sourced Prolia (NCT05245669)
- 2025-10-29Results posted on the registry: Massachusetts General Hospital, Denosumab + Placebo (NCT04087096)
- 2025-08-19Results posted on the registry: Biocon Biologics UK Ltd, Bmab 1000 + Prolia® (NCT05345691)
- 2025-07-14Phase 3 first posted: Qilu Pharmaceutical Co., Ltd., QL1206 + Prolia® (NCT07062978)
- 2025-07-09Phase 3 first posted: Prince of Wales Hospital, Shatin, Hong Kong, Denosumab (Prolia) + Zoledronic acide (Aclasta) (NCT07056478)
- 2025-05-29Results posted on the registry: Alvotech Swiss AG, AVT03 + Denosumab (NCT05395091)
- 2025-05-15Results posted on the registry: Alvotech Swiss AG, AVT03 + Denosumab (NCT05876949)
- 2025-05-11Also stopped (withdrawn): Xentria, Inc., MAB-22 + Prolia® (NCT06504966)
- 2025-04-16Results posted on the registry: Redx Pharma Ltd, RXC004 + Nivolumab (NCT04907539)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision