Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 16:42 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Daratumumab Retreatment in Participants With Multiple Myeloma Who Have Been Previously Treated With Daratumumab
NCT03871829 · Janssen Research & Development, LLC · PHASE2 · terminated · last registry update 2025-03-30 · Multiple myeloma · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “The decision was made to discontinue the 54767414MMY2065 study as the Data Review Committee recommendation was early stop of the study for futility.” | Open Targets' class: another study, negative | Registry record, Janssen Research & Development, LLC |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against PSMD1 in multiple myeloma within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2026-03-20Results posted on the registry: Celgene, CC-220 + Dexamethasone (NCT02773030)
- 2026-03-06Results posted on the registry: University of Colorado, Denver, Selinexor + Pomalidomide (NCT04925193)
- 2026-02-10Results posted on the registry: National Cancer Institute (NCI), Carfilzomib + Dexamethasone (NCT03031730)
- 2026-02-10Also stopped (terminated): National Cancer Institute (NCI), Carfilzomib + Dexamethasone (NCT03031730)
- 2026-02-06Phase 3 first posted: AstraZeneca, AZD0120 + Daratumumab (NCT07391657)
- 2026-01-29Also stopped (terminated): Teva Branded Pharmaceutical Products R&D LLC, Modakafusp alfa + Lenalidomide (NCT05556616)
- 2026-01-22Results posted on the registry: University of Chicago, Ixazomib Citrate + Lenalidomide (NCT02389517)
- 2026-01-05Also stopped (terminated): Universitätsklinikum Hamburg-Eppendorf, Allogeneic Stem Cells + carfilzomib/lenalidomide/dexamethasone (KRD) (NCT05675319)
- 2025-11-20Results posted on the registry: Memorial Sloan Kettering Cancer Center, Carfilzomib + Lenalidomide (NCT02937571)
- 2025-10-30Phase 3 first posted: Regeneron Pharmaceuticals, Linvoseltamab + Carfilzomib (NCT07222761)
- 2025-10-21Also stopped (terminated): University of California, San Diego, Ixazomib + Pomalidomide (NCT03590652)
- 2025-10-07Also stopped (terminated): University of Pennsylvania, Tasquinimod + IRd chemotherapy (NCT04405167)
- 2025-09-10Results posted on the registry: University of Chicago, Elotuzumab + Carfilzomib (NCT02969837)
- 2025-08-06Results posted on the registry: Teva Branded Pharmaceutical Products R&D LLC, Modakafusp alfa + Lenalidomide (NCT05556616)
- 2025-06-26Results posted on the registry: Emory University, Dexamethasone + Ixazomib (NCT02765854)
- 2025-06-04Results posted on the registry: Mayo Clinic, Daratumumab + Dexamethasone (NCT03012880)
- 2025-05-02Results posted on the registry: Gilead Sciences, Magrolimab + Daratumumab (NCT04892446)
- 2025-05-02Also stopped (terminated): Gilead Sciences, Magrolimab + Daratumumab (NCT04892446)
- 2025-03-21Results posted on the registry: Millennium Pharmaceuticals, Inc., Ixazomib (NCT03748953)
- 2025-03-17Phase 3 first posted: Peking University People's Hospital, KPD (carfilzomib, pomalidomide, and dexamethasone) consolidation (NCT06879379)
- 2025-03-12Results posted on the registry: Takeda, Ixazomib (NCT02924272)
- 2025-03-05Results posted on the registry: Dana-Farber Cancer Institute, Ixazomib + Lenalidomide (NCT02916771)
- 2025-03-04Also stopped (terminated): Roswell Park Cancer Institute, Abatacept + Dexamethasone (NCT03457142)
- 2025-02-19Also stopped (terminated): Intergroupe Francophone du Myelome, Ixazomib/Pomalidomide/Dexamethasone (NCT03683277)
- 2025-01-28Results posted on the registry: M.D. Anderson Cancer Center, Ixazomib Citrate + Lenalidomide (NCT01718743)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision