Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-11 16:30 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Glasdegib for Chronic Graft-Versus-Host Disease
NCT04111497 · Fred Hutchinson Cancer Center · PHASE1/PHASE2 · terminated · last registry update 2024-10-29 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Study closed to accrual early due to side effects of study drug.” | – | Registry record, Fred Hutchinson Cancer Center |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against SMO within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2025-10-23Also stopped (terminated): European Organisation for Research and Treatment of Cancer - EORTC, Sonidegib + Cisplatin (NCT04402073)
- 2025-08-21Results posted on the registry: Eli Lilly and Company, LY3039478 + Taladegib (NCT02784795)
- 2025-08-21Also stopped (terminated): Eli Lilly and Company, LY3039478 + Taladegib (NCT02784795)
- 2024-12-03Phase 3 first posted: Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS, High intensity therapies + Low intensity therapies (NCT06713837)
- 2024-09-24Results posted on the registry: Sol-Gel Technologies, Ltd., Patidegib Topical Gel, 2% (NCT04308395)
- 2024-09-24Also stopped (terminated): Sol-Gel Technologies, Ltd., Patidegib Topical Gel, 2% (NCT04308395)
- 2024-08-06Also stopped (terminated): Giselle Sholler, Vismodegib (NCT01774253)
- 2024-07-23Results posted on the registry: Genentech, Inc., Trastuzumab + Pertuzumab (NCT02091141)
- 2024-07-03Results posted on the registry: Sol-Gel Technologies, Ltd., Patidegib Topical Gel, 2% + Patidegib Topical Gel, Vehicle (NCT03703310)
- 2024-06-14Results posted on the registry: Hoffmann-La Roche, Alectinib + Vismodegib (NCT03498521)
- 2024-04-25Results posted on the registry: Pfizer, PF-04449913 (NCT00953758)
- 2024-03-06Results posted on the registry: Pfizer, PF-04449913 (NCT01286467)
- 2024-03-04Also stopped (terminated): OHSU Knight Cancer Institute, Abemaciclib + Abiraterone (NCT03878524)
- 2024-01-23Also stopped (withdrawn): OHSU Knight Cancer Institute, Alectinib + Alpelisib (NCT05238831)
- 2023-12-18Results posted on the registry: Pfizer, Glasdegib + Azacitidine (NCT04842604)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision