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Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 06:48 UTC. Every row links to its source record.

Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time

Improving Pain Management After Total Shoulder Replacement Using Bupivacaine Liposome

NCT04134442 · University of Massachusetts, Worcester · PHASE4 · withdrawn · last registry update 2022-07-06 · Decision brief

No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.

What was said, and by whom

Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.

KindQuoteOur categorySource
Stated“A new large meta-analysis was published. The results showed the likelihood that liposomal bupivacaine and nerve blocks no longer offer significant contribution. Decision was made to terminate the study.”–Registry record, University of Massachusetts, Worcester

Also happening at the time. Not shown to be a cause.

Registry events on other trials of drugs against SCN4A within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.

What is not public

  • Internal portfolio and board discussions
  • Unpublished trial data and interim analyses
  • Terms of any partner or licence decision