Live from ClinicalTrials.gov + Open Targets, fetched 2026-11-12 02:55 UTC. Every row links to its source record.
Postmortem · what the sponsor and named sources said, kept apart from what merely happened at the same time
Study of Various Treatments in Non-alcoholic Fatty Liver Disease (NAFLD) Patients Who Have Aspects of Non-alcoholic Steatohepatitis (NASH)
NCT04147195 · Novartis Pharmaceuticals · PHASE2 · terminated · last registry update 2023-08-21 · Decision brief
No research has been run for this trial yet, so only the registry's own reason and the timeline are shown.
What was said, and by whom
Stated is the sponsor's own words; Reported is a named third party. The category is our label from a fixed list; the quote is the evidence.
| Kind | Quote | Our category | Source |
|---|---|---|---|
| Stated | “Sponsor Decision” | – | Registry record, Novartis Pharmaceuticals |
Also happening at the time. Not shown to be a cause.
Registry events on other trials of drugs against NR1H4 within 12 months either side of this trial's last update, live from ClinicalTrials.gov. Nothing here was stated as a reason.
- 2024-07-25Results posted on the registry: Gilead Sciences, Seladelpar 10 mg + Placebo (NCT04620733)
- 2024-07-16Results posted on the registry: University of Maryland, Baltimore, pravastatin and chenodeoxycholic acid, after metformin and placebo + valacyclovir, chenodeoxycholic acid, and enalaprilat, after polysorbate 80 and placebo (NCT04640571)
- 2024-07-05Phase 3 first posted: Intercept Pharmaceuticals, FDC tablet (OCA 5 mg + BZF 400 mg SR) (NCT06488911)
- 2024-06-05Phase 3 first posted: Assistance Publique - Hôpitaux de Paris, Bezafibrate 400 mg in addition to UDCA therapy + Bezafibrate 200 mg in addition to UDCA therapy (NCT06443606)
- 2024-05-16Phase 3 first posted: Shenzhen HighTide Biopharmaceutical Ltd., HTD1801 + Dapagliflozin (NCT06415773)
- 2024-04-25Phase 3 first posted: Ipsen, Elafibranor (NCT06383403)
- 2024-04-15Phase 3 first posted: Xijing Hospital of Digestive Diseases, Fenofibrate + UDCA (NCT06365424)
- 2024-04-09Phase 3 first posted: Shenzhen HighTide Biopharmaceutical Ltd., HTD1801 + Placebo (NCT06353347)
- 2024-04-09Also stopped (terminated): Nottingham University Hospitals NHS Trust, Ursodeoxycholic acid (NCT05526807)
- 2024-04-08Phase 3 first posted: Shenzhen HighTide Biopharmaceutical Ltd., HTD1801 + Placebo (NCT06350890)
- 2024-03-06Phase 3 first posted: Hopital Foch, Ursolvan + Placebo (NCT06294847)
- 2024-02-15Phase 3 first posted: Leadiant Biosciences, Inc., Chenodeoxycholic acid + Chenodeoxycholic acid Placebo (NCT06260748)
- 2024-02-06Also stopped (terminated): Intercept Pharmaceuticals, INT-747 + Ursodeoxycholic Acid (URSO) (NCT00550862)
- 2023-12-26Results posted on the registry: Novartis Pharmaceuticals, Tropifexor + Licogliflozin (NCT04065841)
- 2023-12-18Phase 3 first posted: Han Ying, Fenofibrate + Placebo (NCT06174402)
- 2023-11-29Results posted on the registry: Gilead Sciences, Cilofexor + Placebo (NCT03890120)
- 2023-11-29Also stopped (terminated): Gilead Sciences, Cilofexor + Placebo (NCT03890120)
- 2023-11-13Phase 3 first posted: Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia, 500 mg of ursodeoxycholic acid (UDCA) (NCT06127355)
- 2023-09-29Phase 3 first posted: Gilead Sciences, Seladelpar 10 mg + Placebo (NCT06060665)
- 2023-07-27Results posted on the registry: Gilead Sciences, Cilofexor (NCT04060147)
- 2023-07-27Also stopped (terminated): Gilead Sciences, Cilofexor (NCT04060147)
- 2023-06-15Phase 3 first posted: Tanta University, Ursodeoxycholic acid (NCT05902468)
- 2023-06-07Results posted on the registry: Ethan Weinberg, Ursodeoxycholic Acid (NCT03602976)
- 2023-06-07Also stopped (terminated): Ethan Weinberg, Ursodeoxycholic Acid (NCT03602976)
- 2023-03-02Phase 3 first posted: Xijing Hospital of Digestive Diseases, Placebo Combined With Ursodeoxycholic Acid + Fenofibrate Combined With Ursodeoxycholic Acid (NCT05751967)
What is not public
- Internal portfolio and board discussions
- Unpublished trial data and interim analyses
- Terms of any partner or licence decision